Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
DLD2
Systematic Name
YDL178W
Alias
AIP2
Strain
S288c
Description
D-2-hydroxyglutarate dehydrogenase, and minor D-lactate dehydrogenase; mitochondrial matrix protein that oxidizes D-2-hydroxyglutarate (D-2HG), an oncometabolite, to alpha-ketoglutarate with a minor role in lactate catabolism; located in the mitochondrial matrix
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>DLD2 YDL178W
ATGCTAAGAAACATTTTGGTGAGAAGTACTGGCAGCAATTTCAAATTTGCTGGCAGATAT
ATGAAATCATCAGCTCTTTTAGGATACTATAGAAGAGTTAACTATTATTCGACCAAGATA
CAAACCAGACTGACTAGCGAAAACTATCCAGACGTGCATCGAGACCCTAGATTCAAAAAA
TTAACGTCCGATGATCTAAATTATTTTAAATCTATTTTATCGGAACAAGAAATATTAAGA
GCCAGCGAATCAGAGGATCTTTCATTTTATAATGAAGATTGGATGAGAAAGTACAAAGGA
CAGTCCAAGTTAGTATTGAGACCTAAGTCAGTGGAAAAAGTTTCTTTAATCTTAAATTAT
TGTAATGATGAAAAAATTGCCGTTGTCCCACAAGGCGGTAACACGGGGTTGGTAGGTGGT
TCTGTGCCCATTTTTGATGAATTAATTCTATCTTTAGCAAATTTAAACAAAATAAGAGAT
TTTGACCCTGTATCAGGTATCTTGAAGTGTGATGCTGGTGTAATCTTGGAAAATGCTAAC
AATTACGTAATGGAACAAAATTATATGTTTCCGTTGGATCTGGGAGCTAAAGGTTCCTGC
CATGTTGGTGGCGTGGTTGCAACCAACGCTGGAGGACTAAGGTTATTGCGTTATGGCTCA
CTACATGGAAGCGTTTTAGGCTTAGAGGTGGTAATGCCCAATGGTCAAATTGTTAATAGC
ATGCATTCCATGAGAAAAGACAACACCGGTTATGATCTGAAACAGCTGTTCATTGGCTCA
GAAGGTACTATCGGTATCATCACTGGTGTTTCAATCTTGACTGTTCCTAAGCCAAAAGCG
TTTAATGTATCTTACTTGTCTGTTGAAAGTTTTGAAGACGTTCAAAAAGTCTTCGTCAGA
GCCAGGCAAGAATTATCTGAGATTTTATCCGCTTTTGAATTTATGGATGCTAAATCTCAA
GTATTGGCCAAGAGCCAATTGAAGGATGCTGCCTTCCCTTTGGAGGATGAGCATCCATTT
TATATTCTTATCGAAACGTCAGGGTCAAACAAAGATCACGATGATTCCAAACTTGAAACA
TTTTTAGAAAACGTCATGGAAGAGGGCATAGTAACGGATGGTGTAGTGGCACAAGATGAA
ACCGAACTCCAAAACTTGTGGAAGTGGAGAGAAATGATTCCAGAGGCAAGTCAAGCTAAT
GGTGGTGTTTACAAATACGATGTTTCTTTACCACTAAAGGACCTATATTCTTTGGTTGAA
GCCACTAATGCAAGACTTTCTGAAGCTGAATTAGTGGGTGATTCGCCCAAACCAGTGGTG
GGCGCCATTGGATACGGTCACGTGGGTGATGGTAATCTACACTTAAATGTTGCAGTTAGA
GAGTACAACAAGAACATTGAAAAGACTTTGGAACCATTTGTCTACGAGTTTGTTTCCTCA
AAACATGGTTCCGTTAGTGCCGAACATGGGCTAGGTTTCCAAAAGAAAAATTACATTGGC
TATTCTAAGAGCCCGGAAGAGGTCAAGATGATGAAGGATTTGAAGGTTCATTATGATCCT
AATGGAATTTTAAACCCTTACAAATACATTTGA
Promoter Sequence
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>DLD2 YDL178W
AAAAGCGTAATACCAAAAAATGTGTACGGTATTAACACCACAAGACATCGGATATTTCTC
GGATGCTTGATATTAGCTGCCAAAACTCTGAACGATTCTTCTCCCTGGAACAAACACTGG
ACCACGTACACAGAAGGTTTACTCAGAATACGTGAGGTGAATACCATCGAACGAGAACTA
TTAGAATATTTAAATTGGGATGTGAGGATAACTACACCGGATTTGATTGATTCTCTTTCT
TACTTCCTCGGGCCTATCAAGGAACAACTATTTTTACAAAGGAGACAAGAAATGCTGTTG
TTCAATGCACCAAGTCCCGGCCAACTGAAAGAATATATAAATCATAGAAGACCGGTTTCG
CATTCTAGAACTTCTTCTGCTATATCGGTTCCTTCACTGACATCCATGGCAACAGTTTCG
ACAACAGACTCAAGGTCTTCTCTACTGGCAAAATACCAACCGTCCCTACCGTTGGTGGAA
TCTGACAACTTCAACAAAAAAAATCATGTGCCGTTAAGGAATAATAACGATATCTGTAAT
AATTTCAGGGCAGAGGAAAACATACACTCAGTAAACCATATTGATGTAACAATGGGAAGT
TCACCAGTAATGTCGCATAAGCCCACAATTCACCAACGGTTAAATTTTACAAGGAGGGGC
TGGTCATCGTTTTTCAAGCAATAATTCTAAGTTACTCGCCTTTTACAAGCTCTATAAATA
TTCTTTTCCGTTCTTTAGTTGTCTTAACTTTGTACAATATGAATAACCATCGTTTCTAGG
CTACTAAAAAAACACCATACTACATAAACAAATATCTAATAATGAATACTCTTGGCATTC
GTCTTGTTTCTCGAGGAATATCGGCCGAGTTTTTTTCATTTTGACAGGTTATATAATTCA
AAATCTATCTGACTCTGAAAAAGTGGTAATAAATGCATTGACAACTTCTTCTCTTTATTT
TACAGACATTAATCCAGCACTACAAGTGGCATATAACAAG
Chr coordinates
Chr IV from 139522-141114