Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PPH22 Systematic Name
YDL188C Alias
PPH2 Strain
S288c Description
Catalytic subunit of protein phosphatase 2A, PP2A; functionally redundant with Pph21p; C-terminally methylated; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; protein abundance increases in response to DNA replication stress; dephosphorylates Tel1p/Mec1p-phosphorylated Cdc13p to promote telomerase release from telomeres at G2/M; PPH22 has a paralog, PPH21, that arose from the whole genome duplication External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PPH22 YDL188C
ATGGATATGGAAATTGATGACCCTATGCATGGTTCAGATGAAGATCAATTATCACCGACT
CTCGACGAAGACATGAATAGTGATGACGGCAAAAATAATACGAAGGCGCGTTCTAATGAC
GAAGACACAGATGAAGAGTTGGAAGATTTTAATTTTAAACCGGGGTCCTCGGGTATAGCA
GATCATAAATCCTCCAAACCACTAAAACTGACCAATACAAATATAAATCAGCTTGACCAA
TGGATTGAGCATTTGAGTAAATGCGAGCCACTATCAGAAGACGATGTAGCACGACTATGT
AAAATGGCGGTGGACGTGTTGCAGTTCGAGGAGAATGTTAAACCAATTAACGTGCCTGTT
ACCATTTGTGGTGACGTACACGGTCAATTCCATGACTTGTTAGAACTTTTCAAGATTGGT
GGTCCTTGTCCTGACACCAATTACCTTTTCATGGGTGATTACGTGGATAGAGGATATTAT
TCTGTTGAGACCGTATCTTACCTAGTTGCCATGAAAGTCAGATATCCACATAGAATTACT
ATACTTAGGGGCAATCACGAGTCTAGGCAGATTACCCAAGTATATGGGTTTTATGACGAA
TGTTTGAGAAAGTACGGCAGTGCGAACGTGTGGAAAATGTTTACCGATCTATTCGATTAT
TTCCCCGTTACTGCCTTGGTGGATAATAAAATCTTCTGTTTGCATGGAGGTCTCTCACCC
ATGATAGAGACAATAGATCAAGTTAGAGATTTAAATAGAATACAGGAAGTGCCTCACGAA
GGTCCAATGTGTGACCTTCTATGGTCCGATCCTGATGATAGAGGCGGATGGGGAATCAGT
CCGAGAGGTGCAGGCTTCACTTTTGGTCAAGACATCAGTGAGCAATTCAATCACACTAAT
GACCTATCACTAATAGCAAGAGCTCACCAATTGGTAATGGAAGGATATTCTTGGTCTCAC
CAGCAAAATGTTGTCACCATTTTCAGTGCTCCAAATTATTGTTATAGATGTGGTAACCAG
GCCGCTATTATGGAGGTGGATGAAAACCATAATAGGCAATTCTTACAATACGATCCATCT
GTGAGACCCGGTGAACCAACCGTCACCAGGAAGACACCGGATTATTTCTTATAA Promoter Sequence
Download FASTA
>PPH22 YDL188C
TTGCGTTTCCACCAATCGGTAAACGATTCTACAATGGAACGCACGGATTCATCTCTCTTT
GTTGAACCAAATGGATCCGATCTTCTCGAGTTGAATTGTGCTGTGCTAAGCTGATATGGA
TGCGTGCCATTAATAGCTTCAATTGCGCCACGATGTGAAGATGCAGGTGGCCTCCATTTT
ACAAGTACGTCCTCCATTTTTCCCACAAATACATTTTCTTCTCTTCTTCTTCTGCTTTTT
TGTTTCGAAATCACGAGTTGCCTCACAGAGGGGAACTCACTTCTTGGTAAGAATCTGTTT
TGAGCCTCCGCTTCAGGGCTGTAGGATGGGAAAGTTATGTCGCCCCCATCTAAACCATCT
TCTATACTTGTGTTACACTGCATATTTTTCTAATATTTCTTGGCTATCTGTAAGCAAATC
TACATCCAGGAATAGAGTCCACAAGTATATTCCATATAAAAGCACAGAACTACGAAGTGT
CGCAAATTAGTTGTTTTTTTGGGAACTTGAACCCATACACCGCACCAAATTATTACAATA
TTTTGTGACACAGGACAGAATATTAATAAAAGAAGCGAAACTCTATTCTCCTAAAACTTC
TTCTTGCGGAATTATGTATCAATTAATGCTAAGATTAATCCAAAAGCTTATACGACAACA
ATAGTCGTTGTGCACTTTGAAATACAATCGTGTATTACCCTGACATGACCGGGTAATCTA
GAAGAGGTTATTATTTTCTTTTCCGCTGAATTGTGGAAAAGAGTCGTGGAAAGTTTCAAA
GGGACATCCCCATTTTATAAAACCAATTGAAGGGCTGTAACTAGAGCAAACTTCTTAAGG
TACCAGCCCGCTGCAAAACAGTGTTCGAACAAGAACACGCAAACCCGTTTACTTCTTGTC
CTACCTGCTCTCTTTCCTTTCCGGTTATTGTTCCTGTTACGTCTTTTTTTGAATTTTATA
TTATTGGCACTTCTGTATAACTGGCTTTCATTCGAAAAAA
Chr coordinates
Chr IV from 124998-123865
