Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
UFD2
Systematic Name
YDL190C
Strain
S288c
Description
Ubiquitin (Ub) chain assembly factor (E4); forms branched Ub chains on substrates destined for degradation, catalyzing K48-linked multi-monoubiquitination of K29-linked Ub chains assembled by the Ub-ligase Ufd4p; involved in the Ub-fusion degradation pathway, OLE membrane fluidity pathway, stress response survival and the ERAD pathway for misfolded proteins, where it promotes ubiquitination and transfer of ERAD substrates to Rad23p; U-box family member; homologous to human Ufd2a and Ufd2b
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>UFD2 YDL190C
ATGACCGCCATAGAAGATATTTTACAAATCACCACCGATCCTTCCGATACCCGTGGCTAC
TCTCTATTGAAGTCCGAGGAAGTGCCTCAAGGCTCAACTCTTGGAGTTGATTTTATTGAT
ACGCTACTATTATATCAACTCACCGAGAATGAGAAGTTGGATAAACCGTTTGAATATTTG
AACGATTGCTTTCGCCGTAATCAGCAACAAAAAAGAATCACCAAAAACAAGCCAAATGCT
GAGTCATTACATTCCACTTTCCAAGAGATTGATCGTCTTGTCATTGGCTATGGTGTCGTT
GCCTTACAAATAGAAAACTTTTGCATGAATGGTGCTTTCATCAATTATATCACTGGAATT
GTTTCTAACGTTAACTCATATACTGATTTCCTTTCCCAAATCATTCAAAGAGCCATATTA
GAAGGTACCGCTTTGGATTTACTTAACGCTGTTTTCCCGACATTATTAGAATACTGTAAT
AAACATGTCAGCCATTTTGATTTGAACGAATCTGTAATTTACAATAACGTTCTTACCATT
TTTGAGTTATTTGTTACATTTAAACCTATTGCAGAAATATTCACTAAAATAGATGGTTTT
TTTGCAGACTATAGCTGTAAACCACAGGATTTTGAAAGGAAAACGATATTGGGGCCTATT
TTATCTCTTTCTCCCATAGAAGCTGCTGTGGCAATCCGGAACTACGGCGATAACCTTTTG
CGTTCCAAACAACAGACAGCCATGATCCATGAATCTCTACAAGCTGAGCATAAAGTTGTC
ATAGATAGACTCTTTTTTATTGTCGATAAGCTTGTTCGTGGCTCCTTAAACTCAAGGACT
GATATGATTAGTTATTTTGCCCATATCGCTAATAAAAACCATTTACGTAGAGCCGATCAT
CCACCATTCAAAGAACTATCCTCTAACGGATTTATGTCCAATATCACTTTGTTATTGGTT
AGATTTTCTCAACCATTTCTAGATATTTCATATAAGAAAATCGACAAGATCGACGCAAAT
TACTTCAACAACCCAAGTTTATTTATTGATTTATCAGGGGAAACACGATTAAATTCTGAT
TTTAAAGAGGCAGATGCATTTTATGACAAGAACAGAAAAACAGCAGATTCTAAGCCAAAC
TTCATCTCTGATTGCTTTTTCTTGACATTAACCTATTTGCATTATGGTCTGGGAGGTACA
TTATCATTTGAAGAGAAGATGGGATCTGAAATCAAAGCGTTAAAGGAAGAAATTGAAAAA
GTAAAGAAAATAGCTGCGAACCACGATGTCTTTGCCAGATTCATTACAGCACAATTATCC
AAGATGGAGAAGGCGTTGAAAACAACAGAATCTTTGCGATTTGCTCTTCAAGGGTTCTTC
GCTCATAGATCTCTTCAACTAGAGGTTTTCGACTTTATTTGTGGTGCATCTACGTTCTTG
ATTCGTGTTGTGGATCCTGAACACGAATTTCCGTTTAAACAAATTAAATTGCCATTAATT
CCGGACCAAATAGGTGTTGAAAACGTGGACAACGCTGATTTTTTGAGAGCGCATGCTCCA
GTGCCTTTTAAATACTATCCAGAATTTGTTGTAGAAGGTCCAGTTAACTATTCTCTATAC
ATTTCGAAGTACCAGACCTCTCCAATCTTCAGAAATCCACGTCTGGGATCGTTTGTTGAG
TTTACAACAATGGTCCTCCGTTGTCCTGAATTGGTTTCCAACCCACATTTAAAAGGTAAA
TTAGTGCAGTTATTAAGCGTTGGTGCTATGCCTCTAACAGACAATTCCCCCGGATTCATG
ATGGATATATTCGAACACGACGAATTAGTTAACAAGAATCTGTTATATGCTCTACTAGAC
TTTTATGTTATTGTTGAAAAAACAGGCTCTTCTTCACAATTTTACGATAAATTCAACAGC
AGATATAGCATATCAATAATTTTGGAGGAGCTTTATTACAAGATACCATCTTATAAAAAC
CAATTGATCTGGCAGTCTCAAAACAATGCTGACTTTTTTGTGAGGTTCGTTGCTCGTATG
TTGAATGACTTGACTTTCCTGTTGGATGAAGGCCTAAGTAATTTGGCTGAGGTGCATAAT
ATCCAAAATGAGCTGGATAATCGTGCAAGGGGCGCGCCACCAACAAGAGAGGAAGAGGAC
AAAGAACTACAAACAAGATTGGCGTCTGCTTCCAGGCAAGCTAAGTCCTCGTGTGGATTG
GCCGATAAATCGATGAAACTGTTCGAAATCTATTCGAAGGATATACCGGCTGCATTTGTC
ACACCAGAAATCGTATATAGACTGGCAAGTATGCTAAACTATAACTTAGAGTCACTTGTC
GGTCCCAAATGCGGGGAACTAAAAGTGAAAGACCCACAAAGTTATTCATTCAACCCAAAA
GATTTGTTGAAAGCCTTAACAACTGTTTATATCAATCTTTCCGAGCAATCAGAGTTCATC
AGTGCTGTCGCTAAAGATGAAAGATCATTTAATAGAAATCTCTTTGTTCGCGCAGTTGAT
ATTCTTGGTAGAAAAACTGGTTTAGCATCTCCAGAGTTCATCGAAAAACTATTGAACTTT
GCCAATAAAGCCGAAGAGCAAAGAAAGGCTGATGAAGAGGAAGATCTTGAGTATGGTGAT
GTTCCTGACGAGTTCTTAGATCCTTTGATGTACACAATTATGAAGGATCCTGTCATTTTA
CCAGCATCCAAGATGAATATTGATAGAAGCACGATCAAAGCACATCTGCTTAGTGACTCT
ACTGACCCGTTTAATAGAATGCCTTTAAAACTAGAGGATGTAACACCTAATGAAGAGTTA
AGGCAAAAGATTCTTTGTTTCAAAAAACAAAAAAAGGAAGAAGCAAAACATAAAGCAAGC
GAGTGA
Promoter Sequence
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>UFD2 YDL190C
AATATTCTGTTATTGTTCGATTTTTCAATACTCTCACTTGAGGAAGCACACTCTTCCGGT
TTTTTGTTCAGCTGCAACTCTTGTAAGAGTGGCTTTCCTTCAATCTTTTGGAAATTCTCA
CCTTTGAAAAGAATCACACAACTATCTTGAGTTCTTGCCAAAACATGGTTCAAGTTGTGG
TACTCAGCTATTTGGTGCGATAGAAGCCTATAATATGAATTCATCGGTCTTAGCTGAAAT
GATTCTGTGTTTGAGTTTATGAATGACACTATGGAATTTTCCAGCTCTATTATAAAGATA
CGGTCCTGTGGTTTCTGGAACAAGCCCGTTTCCATAGCGGGTGTCAATCCCCAGTTTCGA
GAATCTAGTGCTGTCATCACCTACTTCTGCCCTAACTCCTTATATACTTGAAGAGACTTG
AATATCTTAGTTGTTAGTACGATACGAAATAACTAAAAAATTAATTAAAATAAAATAAAT
CGTGCGCCCATTATAAGATGCACGTTTCAACATACTGTCACCACGGCTTGCTGGTACAAT
ATGGCTCAATTGCCTACGCCAAAACTTGTCGAGTTGTATGTGAAAGAAAGAAGAAACAGA
TAGGCTAACCCGCATATGACACTAGCCAACGCTTCTTAATCGATATTCTTATTATATCAA
TATTATTTTGCGCTTAACGATTCATCCTTTCGTCGAGGACGCTATTTTGTCAGTATTCGT
CAGAGGCGATAGTCTGTCTTTATTACAAAAGGTGAATTGAAGATCAAAGGTAGATTCTAA
CCATTGGCAACAAAATAATAGAGGTGTACGCCGCAATCATTGTTAATCATTAAGTAATTG
CCATTTTATTCACATTTTTAGACTCAACCACTTGCTGTTGCCACAGTAAACGTTAATTAT
ATCTTTGAGAATTGTGTCAGCCAATAGAAAGGTAAAGTTGACCACAAGTTGTTTAAGGGG
AAAAGTTAACTTTGAAAGTAGAACCCTCATTCCATAGATC
Chr coordinates
Chr IV from 121592-118707