Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
HEM3 Systematic Name
YDL205C Alias
OLE2 Strain
S288c Description
Porphobilinogen deaminase; catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in heme biosynthesis; localizes to the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p, but not by levels of heme; human homolog HMBS can complement yeast mutant and allow growth of haploid null after sporulation of a heterozygous diploid External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>HEM3 YDL205C
ATGGGCCCTGAAACTCTACATATTGGTGGGAGAAAATCGAAATTGGCGGTAATACAATCC
AACCATGTTTTAAAACTGATCGAAGAAAAGTATCCGGACTACGACTGCAAGGTTTTCACT
TTGCAAACTCTTGGTGACCAGATTCAATTCAAACCTTTGTACTCATTTGGCGGTAAAGCT
TTATGGACAAAGGAGTTGGAAGACCATCTTTACCATGACGATCCCTCAAAGAAGCTTGAC
TTGATCGTTCATTCTCTGAAGGACATGCCCACTTTACTACCAGAGGGTTTCGAGCTGGGG
GGTATCACTAAGCGGGTCGATCCAACAGATTGTCTTGTCATGCCCTTTTACTCTGCTTAT
AAGTCTCTGGATGACCTTCCAGACGGGGGGATTGTGGGAACCTCATCCGTGAGAAGATCT
GCTCAGCTAAAAAGAAAATACCCACATTTGAAATTTGAAAGTGTCAGAGGAAATATACAA
ACTAGATTACAAAAACTAGACGACCCAAAATCTCCGTACCAATGCATCATCTTGGCGTCT
GCTGGGTTGATGCGTATGGGGTTGGAAAACAGAATTACGCAGCGATTCCATTCGGATACA
ATGTACCATGCAGTTGGACAAGGCGCCCTGGGTATAGAAATTAGAAAGGGTGACACCAAG
ATGATGAAGATTCTTGACGAAATTTGCGATCTAAATGCAACTATATGTTGCCTTTCGGAG
CGTGCTTTGATGAGAACTTTAGAGGGGGGTTGTTCCGTTCCTATTGGTGTGGAATCTAAA
TACAATGAAGAGACTAAAAAATTACTATTAAAGGCCATTGTAGTTGACGTTGAAGGCACA
GAAGCAGTAGAAGACGAAATTGAAATGCTAATAGAAAATGTTAAAGAAGATTCCATGGCG
TGTGGTAAGATACTAGCTGAAAGAATGATTGCCGATGGCGCAAAGAAAATTCTGGATGAA
ATTAATTTAGACAGAATCAAATGA Promoter Sequence
Download FASTA
>HEM3 YDL205C
AGCAAAGCTCGCACCCGACTTGCTAGGGTTAGTCCAGTATATCAATCCCGTCTTGTTCTG
ATGACCTGCTTCACCGGGAGCGTTAGCATTTCTACTGTTATTCAAATTCGCGTTCTTATT
GGTAGTCGTATTCCTATTCATGTTGATGATAGTTTGTGGCAAGTTGAGACAAGCAATTGA
ACAAGTTATTACTACTATTGCTACATAATTGATCTGCTTTTCAATCCCTTTTATATATTT
TTTTCATCAAAGTAGCAAGCTTTATCGTTTGAGGGTGGAAATAAGGGTGAACAATAAGGG
GAGATTGCCTATGCGCCTAAACGTCACCGTCTAACCTTGTTCTCCTTTCAACAAAAACGC
CTTGCGTTCTTATTGCTAGGCCACAATTACAAGCATCTCAAATGGGGCATTATCACACCG
GTACCACCGACACATTCTGCTGCTACCCTTGTAGTTTAAGTTAACTTTGCGTCCACTTTT
CGTAATTATTTTGCTCCCTGGCAGCACCGGGGGTAAAGATGTCTTTCTGGCTAATGCAGT
CATCCTTACATTGTCGTTCGTACGGCAGTCCAGGATTTTTGACCATCTTTACGCAGCAAT
TCCCATATAACATTCCTTCTCTCCTTGTCAATTGACCCTGGGGAGCGTCTGACCAATAAG
AAACCGATGAGTAAGCAATGAAGGTCTTTTTTTTGGCTACGAAAATTTCAGCAATTTTTT
AAAGTGAAAAAGTAAAAAAATCAAACATAAAAAAAGAAAGAAAATGAAAAAGTAAAGGAA
CGCTTTATATAAACGAGGCTACTAACTATCTGTATTATTGCTACACATAGCCTGAATTCA
AGGTCATTGGCAGATTGACGCTCGTGTTTGCATGGTACAGGGCTGTATTAGATTTTGAAT
ATTCTGTTCTTCTCATCCCGTATTAATATCTAGAACAATAGAAAAAAAGAAAAGCGAAGA
AAATCTAGATAAATTTGTAGTTGGTAAATACACACGTACT
Chr coordinates
Chr IV from 93745-92762
