Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
DOA4
Systematic Name
YDR069C
Alias
DOS1, MUT4, NPI2, SSV7, UBP4
Strain
S288c
Description
Ubiquitin hydrolase; deubiquitinates intralumenal vesicle (ILVs) cargo proteins; required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins destined for the vacuole; DOA4 has a paralog, UBP5, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>DOA4 YDR069C
ATGGAGCAGAATATTATTAGTACCATAAGGGATGAGTGTATTCGTCACCGGTCGAAGTAC
CTTACGATAGCACAACTAACCGCTATTGCAGAGGCTAAAATTAACGAATTCATCATAACT
GGTAAGGCAAAAGATCAAGATTTGAGCAGTCTTCTAGATAAATGCATCGATATTTTATCT
ATTTACAAGAAGAACTCGAAAGATATCAAAAATATTATATCGTGCAAAAATAAGGGTGCA
ATGATTAGTTCAAATTCCGTAATGATTATTCAATTAAATTATGTTTACTACAAGGTAATT
CACATTATTGTAACAACCAATATTCCTCATTTAAGTGAATTCGCCAAGATTAAATTACAT
AAGAGCACGAGTGATGAGGGCAACGGTAATAACAACAATAATGAATTTCAACTCATGAAC
ATTTACAACACTTTGCTGGAAACCTTATTAAAAGATGAAAACATTGCAAAAATAAAAAGT
TTCATTAAGTCTTCCATAAAACAAACAAAATTGAACCATGAGCAAGAAGAATGTAACCTG
ATGAGAACGGGTTCCTATATCACTTCCAATCAATTAAACTCCCTAATAAGTTCATCAGCA
AATTCTGCTTCCTCCCAAATGGAGATACTACTGATAGATATACGATCAAGGTTGGAATTC
AACAAGTCACATATTGATACAAAAAATATTATATGCCTGGAGCCTATTTCTTTTAAAATG
TCATATTCAGATCATGATTTGGAGAAAAAATCATTAATTACTTCTCCTAATAGTGAGATT
AAAATGTTTCAAAGTAGAAATCTTTTCAAGTTTATCATTCTCTATACAGACGCAAACGAA
TACAATGTTAAACAGCAGTCTGTCCTGTTGGACATTCTGGTGAATCATTCCTTTGAAAAA
CCAATATCCGATGACTTTACCAAAATTTTCATTCTGGAATCTGGTTTTCCAGGTTGGCTT
AAGTCAAATTATGGGAGGCAAGTATCATCATCTTTTCCATCAAATAACAATATTAAAGAT
GATAGTGTTTATATTAATGGTAACACTTCTGGCCTAAGTTTACAACATTTACCTAAGATG
TCTCCCAGTATAAGACATTCAATGGACGACTCTATGAAAGAAATGCTAGTTGCGCCTACT
CCATTAAATCATCTTCAACAACAGCAACAACAGCAATCAGACAATGATCATGTGCTAAAA
AGATCTTCAAGTTTCAAAAAATTATTCTCAAATTATACGTCTCCTAATCCGAAGAATTCA
AATTCAAACTTATATTCTATATCTTCGTTGTCCATATCTAGTTCACCATCGCCTTTACCT
CTACATTCGCCTGACCCAGTTAAGGGCAATTCATTGCCAATCAATTATCCGGAAACGCCA
CATCTTTGGAAAAACAGTGAGACAGATTTTATGACAAATCAAAGAGAACAGTTGAATCAC
AACTCTTTTGCTCACATAGCTCCTATCAACACGAAGGCCATCACTTCTCCATCAAGAACT
GCCACACCGAAGTTACAACGCTTCCCGCAAACAATTAGTATGAACCTTAATATGAACTCC
AATGGACACAGTTCTGCCACCTCTACCATTCAACCTTCGTGTCTATCCTTGTCTAATAAT
GACTCTTTAGATCATACAGATGTTACACCAACTTCTTCTCATAATTATGACCTTGATTTC
GCGGTTGGTTTGGAAAATCTAGGAAATTCGTGTTACATGAACTGTATCATTCAGTGTATC
TTAGGTACACACGAATTAACCCAAATCTTTTTGGACGATTCATATGCTAAACACATCAAT
ATTAATAGTAAGTTGGGATCGAAAGGTATTCTGGCAAAATATTTTGCAAGGTTGGTTCAT
ATGATGTATAAGGAACAGGTTGATGGTTCAAAGAAAATTTCCATATCACCGATAAAATTT
AAATTGGCATGTGGATCTGTTAACTCATTATTTAAGACTGCATCCCAACAGGACTGCCAA
GAGTTTTGCCAATTCCTTCTAGATGGTCTTCATGAAGACTTGAACCAATGCGGTTCAAAC
CCACCTTTGAAGGAGCTTTCTCAAGAAGCTGAGGCGAGAAGAGAAAAACTGTCTTTGCGA
ATTGCCTCGTCAATTGAGTGGGAACGATTCTTGACTACTGATTTCAGTGTTATTGTCGAC
TTATTTCAGGGACAATACGCCTCACGACTAAAATGTAAAGTCTGTAGTCATACCTCGACA
ACATACCAACCTTTTACGGTGCTGTCAATCCCTATTCCTAAAAAAAATTCCCGAAATAAT
ATTACCATTGAAGATTGTTTCAGAGAGTTCACCAAATGTGAGAACTTGGAAGTGGATGAG
CAATGGTTGTGCCCACATTGTGAAAAAAGGCAGCCCTCCACGAAACAATTGACAATAACG
AGATTACCGAGGAATCTGATAGTCCATTTAAAGAGATTTGATAATTTATTAAACAAAAAT
AATGACTTCGTCATATACCCTTTTTTGTTGGACTTGACTCCATTTTGGGCCAATGATTTT
GACGGGGTTTTTCCTCCAGGTGTTAATGACGATGAACTACCAATAAGGGGACAAATACCA
CCTTTTAAGTATGAATTATATGGTGTAGCATGCCACTTTGGTACTTTGTATGGTGGTCAT
TATACAGCCTATGTGAAAAAGGGATTAAAGAAGGGATGGCTATATTTTGATGATACCAAA
TATAAACCTGTCAAAAACAAAGCCGATGCAATTAACTCTAATGCATACGTTTTGTTTTAT
CACCGCGTCTACGGTGTTTGA
Promoter Sequence
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>DOA4 YDR069C
CCCTACATCCTTGACCGTACTGAGATATCACTGCTTAATTCCGGTGATTGGGTTCTTTTC
AGTTCTTGGAGAGATATACGTACTACCTTCCTTTTTTTTTAAGGATACCTTTACTGTAAA
GGGTTTGTTCCTGTATCAACCCCTTCTTCCTGTACAGAATCTAAGGGAACCGTAAAAGCA
CATAAGTATATAAAGGTCCCAAGATTTGATTAGGTAGATATGGCCTTTGAGTTGGCTCTT
AGTTTTTTTTGGCCTTGAATACTTGTTCCTACAATACTCCAACAGCAGTTGAAGCCAGAC
CGCAGTATCACATATATAATACACAGGAATATATTTGATAATGTTGAGAACCACTTTTTT
GCGCACTCCAAGACAATTGATGCGTAAATCGCCAAGGGCGTCTTTCTCAATCGTCACTAG
GGCCGCCTTTCCTCACCTAAAGAACAATCAAGATGAAGCTGAGAAAAAAGAACAGGGTTT
GTTTGATAGCAACAAGAAGAGGTTGGACACTTTGGAACACGGCAAGAATCCAGATTATAA
GCAACCTGGAATGGAAGATTTGAAAAAAAAGGGAGATGACGCTAGAATCGAACAAAACAG
GCCAGATGACGGTGTTTATTAAGAAGCACTTGGTACAAACTCGTATATGCATGTAGTTTC
TGTCATACACATATCTATATTCCTTCCCCCCTGGTCCTATCGTATTTAGTCATATCATAT
CATTTATTGATATCTATATAAGTGCAAAACTATAACCATTATTTATTTGCTTTCCACATT
GTTTTACTTCATTTGCTTCAATATCGTTCATTACGTTTAGCGAATGGCTAAGGCCCTTGT
ATTAGTAAAAGCCTAGAAAAAAAAAAAAAAAAAAAAAAAAGGATATGATGTTATATGATA
CGTGTAGTTCATGTATTTATCTTCGGTAGTATAGGGCAGATTTAAGACTGAGTGTGCACG
CTTCCAAAGTTTTTTTTACTATTTGATACATGCTTAAGTT
Chr coordinates
Chr IV from 587719-584939