Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
RRP8
Systematic Name
YDR083W
Strain
S288c
Description
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; methylates adenine (m1A) of the large subunit (LSU) rRNA at position 645; involved in pre-rRNA cleavage at site A2; mutation is synthetically lethal with a gar1 mutation; deletion disrupts telomere maintenance by influencing the expression of neighboring gene STN1
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>RRP8 YDR083W
ATGGCCTTATTTAACGTAGAAGGTTGGTCTATTAAGACAAAAACCGTCGCTTTTGATAAC
AAGACTAATAAGTCTTCAAAAGATAAAAAAAAAAATAATAGAAAAAATGGCAAACTTACA
AGAGAACAGAAGTTGAAAGAAGAGACAGAGGCTGAGTTGAAGGAACAAGTGGAAGACATT
CCTTCCGAAGGATCAGTAGCCAAAGACATCCCAAAAAAAAACCAAGAGAAAAGTGATCAA
AATGAAACGAGCAAGAAACGCAAGCACGATGAAGAAGCCCCTCTGATGCAAGTAAAAGAA
AATATTGAAAAACCTACAAAGAAGCAACTAACCCCTTTACAACAAAAGATGATGGCTAAA
CTGACTGGTTCTAGATTTAGATGGATCAATGAACAACTGTATACAATTAGCTCTGATGAA
GCTTTGAAATTAATAAAAGAACAACCACAATTATTTGACGAATATCATGATGGTTTTAGA
TCACAAGTGCAAGCATGGCCGGAAAATCCAGTTGATGTTTTTGTTGACCAAATTCGTTAT
AGATGCATGAAACCTGTGAATGCTCCAGGTGGGTTACCAGGTCTTAAGGATAGTAAAGAA
ATAGTTATTGCTGATATGGGGTGTGGTGAAGCTCAATTAGCATTAGAAATCAACAATTTT
TTCAAAAATTACAATAAGAAAGCGAAGAAATATTTGAAAAGACGCCATAAAGTCCACAGT
TTTGATTTGAAGAAAGCTAACGAAAGAATAACTGTGGCAGATATTAGAAATGTGCCGCTA
CCAGATGAGTCCTGTACTATAGTGGTCTTCTGCCTGGCTCTAATGGGTACAAATTTCCTC
GATTTCATAAAAGAAGCTTATAGGATTTTAGCGCCAAGGGGTGAATTATGGATCGCAGAA
ATTAAATCAAGGTTTAGTGACGGCAAAGGTAATGAATTTGTAGACGCTTTGAAGCTGATG
GGATTTTTTCACAAAAAGACCTTCGACGAGAATAAGATGTTTACAAGATTCGAATTTTTC
AAGCCACCTGCGGAGATTATTGAAGAGAGAAGGCAGAAATTGGAAAGAAGACAAAAGTTT
ATTGAAGTTGAAACTGAGAAGGAAGAATTAGAAAAGAAAAGACGGAAAATTGCCGAAGGA
AAATGGCTCTTGAAGCCCTGTATTTATAAAAGAAGATAA
Promoter Sequence
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>RRP8 YDR083W
AGTAAACCCGGATTTTGTAGGTATAGGGTACAAAACCCCAGAAAGTAAAAGAAATGAAAC
TACTTTCATCGAGCAACTGCAAGAAGAACGCTTGAAGGATGAATTAGAAATTATTAGTCC
ATACAATAGCACAGATACTTCGAATAGTGTGCATTCCTTGTCATTTCGGTTTGTATCGTC
GCTAAAGGATTTTCCTGAAACTCACTTTTTGAATTCAGGTGATCAAATTGACAACGGCAA
TGACGAACAGTTAAAAAAACTAGAATATCAAAGCGCTAATCTACCTGTGATGATTCCCAA
TAGGACATCAGCAAAGTCAAACTTGATGTTGATCCTATTAGGACTACAAATGAAAGAGAT
TTCTAATTCTGACCTTTACAAACTAAAGGAAGTACGCAGCGTAGTAACTAGCTTAGCATC
GTTTTTGTTTCAACAACAAAATGTTGGCGTCATGAAATCTTTTGACTCTTTGGAAAAGGA
AGCGTTTCGAGACCTGGTTAATCGTCTAGTCAGCCAGGGTTTGATCGGATTAAAAGATAA
AACAAGTGAGACATTTGATTTGCTTCCTCTAAAAAATCTTTTTGAATATGCTGAAAAACG
TATATCAGTTCTAATGAAGCTACAATGTTATACAGGCACTGTGCAATTAAGTCATGTTCA
GGAAAAGCTACATTTGCCGTACATAACAACGAACGGCATCGTTGATGTTTTCAAAGAATG
TCTTAAAAGGACAAAGAAACAGTATCCTGAGGTACTAAAAAATTGGTGGATTGATCTTGA
TCCGAAGAATGGTATGGAGGACCAAAACAGTGGAATATTATTACATTTGGAATACGCAGC
AGCATATTCATAATTTGTTAGAAAACTCGCATCGTCAATAACGGCGCATCTCTCTAGGCC
TGAAAAATTTTGCGATGAGCTCAAAATAAGATACTATAACTTTATGCATATATTGTATAT
ATATTATATCAAACAAATAAGGACGTTAACGAAATTTTAT
Chr coordinates
Chr IV from 612073-613251