Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
GIS1 Systematic Name
YDR096W Strain
S288c Description
Histone demethylase and transcription factor; regulates genes during nutrient limitation; activity modulated by proteasome-mediated proteolysis; has JmjC and JmjN domain in N-terminus that interact, promoting stability and proper transcriptional activity; contains two transactivating domains downstream of Jmj domains and a C-terminal DNA binding domain; relocalizes to the cytosol in response to hypoxia; GIS1 has a paralog, RPH1, that arose from the whole genome duplication External sources
Open in SGD
Open in KEGG
Gene Sequence
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>GIS1 YDR096W
ATGGAAATCAAGCCAGTTGAGGTTATTGATGGCGTTCCGGTTTTTAAGCCGTCTATGATG
GAGTTTGCAAATTTCCAATATTTCATTGATGAAATTACTAAATTCGGAATAGAAAATGGT
ATTGTCAAAGTCATTCCTCCCAAAGAATGGCTGGAGCTTTTAGAAGGCTCACCTCCTGCG
GAAAGTTTAAAGACTATACAACTAGACTCCCCGATTCAACAACAAGCCAAGCGATGGGAC
AAACATGAAAACGGTGTATTTAGCATCGAAAACGAGTATGACAATAAGTCGTACAATTTA
ACACAGTGGAAGAACTTGGCCGAAAGTCTAGACTCTCGAATAAGTCAAGGTGATTTTAAT
GATAAAACTTTAAAGGAAAATTGCCGCGTAGATAGTCAGCAGGATTGTTATGATTTGGCA
CAGTTACAAATTTTAGAAAGTGATTTTTGGAAAACCATCGCTTTTTCGAAACCTTTTTAT
GCAGTGGACGAAAACTCTTCAATTTTCCCCTATGATTTAACTTTATGGAATTTGAATAAT
TTGCCAGATTCTATAAACTCAAGTAACAGACGGTTACTTACTGGTCAGTCTAAATGCATT
TTTCCATGGCATTTGGACGAACAGAATAAATGCTCTATAAACTACTTGCATTTCGGTGCT
CCCAAACAATGGTATTCCATACCGTCCGCAAACACAGACCAATTTTTGAAAATTTTATCA
AAGGAACCATCAAGTAATAAGGAAAATTGTCCAGCTTTTATTAGACATCAAAACATCATA
ACTTCTCCCGATTTCTTGCGAAAAAATAATATAAAATTTAATAGAGTGGTGCAGTTCCAA
CATGAATTCATCATTACTTTCCCTTATTGCATGTACTCCGGATTCAATTATGGTTACAAT
TTTGGCGAATCTATTGAGTTCATATTAGATCAGCAAGCTGTCGTTAGAAAGCAACCTTTA
AAATGCGGCTGTGGAAACAAGAAGGAAGAGCGAAAATCTGGTCCGTTTTCAAATTTATCT
TATGATTCTAATGAGTCGGAGCAACGAGGCTCCATTACTGATAATGATAACGATTTATTT
CAAAAAGTTCGAAGTTTTGATGAATTACTAAACCATTCCTCTCAAGAGTTACAAAATTTA
GAAGACAATAAGAACCCCTTGTTCTCCAATATTAATATGAACAGACCGCAAAGTAGTTCT
CTTCGGTCTACTACCCCTAATGGTGTAAACCAGTTCCTGAACATGAATCAAACTACCATA
AGCAGAATTTCTTCCCCGTTGTTATCAAGGATGATGGACTTATCAAATATTGTGGAACCC
ACTTTGGATGATCCGGGTTCCAAGTTCAAAAGGAAAGTTTTAACTCCGCAATTACCGCAG
ATGAATATTCCGTCTAATTCTAGTAATTTTGGCACCCCTTCTCTAACTAATACAAACTCC
TTACTATCTAATATAACGGCTACATCAACCAACCCATCGACAACTACAAATGGCAGCCAA
AACCACAATAATGTTAACGCCAATGGCATTAACACCTCTGCAGCCGCATCTATCAATAAT
AACATTAGCAGTACCAATAATAGCGCTAATAATAGTAGTAGTAATAATAACGTTTCCACT
GTGCCTTCTTCAATGATGCATTCGTCCACTTTAAATGGGACTTCAGGTCTAGGCGGCGAT
AACGATGACAATATGTTAGCTTTAAGTTTAGCGACACTGGCTAACAGCGCTACTGCGTCA
CCAAGATTGACGTTACCGCCGCTGTCGTCACCAATGAATCCGAACGGCCACACCTCATAT
AATGGCAATATGATGAACAACAACAGTGGTAATGGTAGCAACGGTAGCAACAGCTATTCT
AACGGTGTGACTACGGCTGCTGCCACAACTACATCAGCGCCTCACAATCTATCCATAGTG
TCCCCTAATCCAACATACAGTCCGAATCCCCTATCTCTTTATTTGACCAACTCCAAAAAT
CCATTAAATTCAGGTCTTGCACCCTTATCACCTTCAACATCTAACATCCCATTTCTCAAG
AGGAATAATGTGGTTACATTAAATATTTCAAGAGAAGCTTCAAAGAGCCCTATATCTTCT
TTTGTAAATGACTATAGATCTCCGTTGGGTGTAAGCAATCCACTCATGTATTCTTCCACA
ATCAACGATTATTCAAACGGTACTGGAATTCGCCAAAATAGTAATAATATTAATCCCTTA
GATGCAGGTCCATCTTTTTCTCCTCTCCACAAAAAACCCAAAATACTCAACGGTAATGAT
AATAGCAATCTGGACAGTAATAATTTTGATTACAGTTTCACGGGTAACAAGCAAGAATCT
AATCCATCAATCTTGAACAATAATACTAATAATAATGATAACTATCGTACATCTTCAATG
AACAATAACGGCAACAATTATCAAGCGCATTCTTCTAAGTTCGGTGAAAATGAGGTCATT
ATGTCAGATCATGGTAAGATTTACATTTGTCGGGAATGTAATAGACAGTTTTCCTCTGGT
CACCATCTAACAAGACATAAAAAGTCAGTTCATTCCGGTGAGAAACCCCATTCTTGCCCA
AGATGCGGTAAAAGATTCAAGAGAAGAGACCATGTTCTGCAACATTTAAATAAAAAAATT
CCATGCACTCAAGAAATGGAAAATACTAAATTAGCTGAATCATAG Promoter Sequence
Download FASTA
>GIS1 YDR096W
TCCTTTGTACTATGTATACCAATGTGATATGATATAGATTTCATATAGGATGTGATGATG
TGTATCACCCGGCACGGCTCTACCCCGCCCTGTGGGGTGTGGAGAAAACGCCGCGCAGAG
CCTTGAGTAGGAAGGGGCTGGGTTCTCCCCTTCCTGCCGGGGTCCGCCCGGCGCCAAGAG
TAAGAGAGCGAAGCCGGAGACGTAATATGAAAAAAATTTTGAGGGGAAAGGGCGTCCGCA
AGGGCAAGGGCAAGGGGAAGGGGTGGCGTTTTGTGCTTCAAGGAATTATATTTCGTTGTT
TTCCGCACTATGGCGGCATTGTGGCAAGTAACTACTTTACGGAGAAAGACTAGAAAATGG
TTACAACTGCCACTATTACCGCTTCGCATTCTCTTGTCTTACAGGTCCCTTGAATTGGCA
TTTACGTTTACATCCGATCCGGTTTTTCACCAAAGAGAAAGGAAAGGAAAGGTAAAAATA
GCAAACCGAAAAAGAAAACAGTATTTTCTCTCTGTTTAGGATTATTACCACTACTTACTG
AAGAGAAGTTTTTAACGTTTATCGTTTGTGTTGAGGTAGAAGTACAAACGCGTGTGTGAG
TTGTGTATTTGAAATTATTATCCTTCTACGCATATCGGGAAAAAGTTAACGGAAAAAACA
AGAAGAAAACCTCCCCCCTCCTCCTCCCGCCATACAGAAGGCAAAAGAAGTTGGTCTGTT
AGGAAGAAAATAGCCAAGTAATAATACGTTTGGCCAGTTGTATTTTTTTTTTGTTTCGCT
AAGTCTCTTGCTTACAGAAACTCTTTGCCCACCACATATTTCATCGTTTTTCCTTTCTGT
TCATCATTAACCTCCATTTCCCAATTTTTTCCAATTTTCAATTTTTTTCACTATTTGTTT
CTTTGTTGGGCGTTTAAAAAGTATTTGCTTCTACAAAGTGAACAACATCGTTGTAATTTT
TTTTTTTTAATTTGAAGAATAGCTACAAAAACAGACTACA
Chr coordinates
Chr IV from 637139-639823
