Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name GRX3
Systematic Name YDR098C
Strain S288c
Description Glutathione-dependent oxidoreductase; hydroperoxide and superoxide-radical responsive monothiol glutaredoxin subfamily member with Grx4p and Grx5p; redundantly protects cells from oxidative damage along with GRX4 and GRX5; with Grx4p, promotes the dissociation of Aft1p from iron regulon gene promoters and subsequent nuclear export in iron-replete conditions, regulating iron homeostasis; involved with Grx4p in the deglutathionylation of Sir2p, restoring deacetylase activity after disulfide stress
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Gene Sequence
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Promoter Sequence
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>GRX3 YDR098C
CATTGCTGATGTGATGACAAAACCTCTTCCGATAAAAACATTTAAACTATTAACAAACAA
ATGGATTCATTAGATCTATTACATTATGGGTGGTATGTTGGAATAAAAATCAACTATCAT
CTACTAACTAGTATTTACGTTACTAGTATATTATCATATACGGTGTTAGAAGATGACGCA
AATGATGAGAAATAGTCATCTAAATTAGTGGAAGCTGAAACGCAAGGATTGATAATGTAA
TAGGATCAATGAATATTAACATATAAAACGATGATAATAATATTTATAGAATTGTGTAGA
ATTGCAGATTCCCTTTTATGGATTCCTAAATCCTCGAGGAGAACTTCTAGTATATTCTGT
ATACCTAATATTATAGCCTTTATCAACAATGGAATCCCAACAATTATCTAATTACCCACA
TATATCTCAATAACAAAACGAACAACATGAGATAAAACACGGCCTTCCCTAGCTGAACTA
CCCAAACGTATAAATGCTTGAACAATTAGTTTAGATCCGAGATTCCGCGCTTCCACCACT
TAGTATGATTCATATTTTATATAATATATAAGATAAGTGACATTCCGTGAATTAATCTGA
TAAACTGTTTTGACAACTGGTTACTTCCCTAAGACTGTTTATATTAGGATTGTCAAGACA
CTGCGGTATTACTCGAGCCCGTAATACAACAATACACAGTTGTTACGGTCCTATAGTGTA
GTGGTTATCACTTTCGGTTTTGATCCGGACAACCCCGGTTCGAATCCGGGTAGGACCTTT
TTTAACTGTGGCTTCTCTGTTGAACCATCAGTTACTTTTTTTTTTTTTCAGAGAATGTGT
GCCGGGTCATGAGATGCCAAACTAAGAGGTCATTAAAATATATTTCAAAGACTAAATGTG
TTCTTTTCAGGTTCCATCTGCATTTTCTTTTAACTACACCTCGTACTGTTATAAACGCCA
CCAAGCAAGATATTACACAGCAGCAAAACTTTTTCAGGAA
Chr coordinates Chr IV from 644930-644178
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