Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
GRX3
Systematic Name
YDR098C
Strain
S288c
Description
Glutathione-dependent oxidoreductase; hydroperoxide and superoxide-radical responsive monothiol glutaredoxin subfamily member with Grx4p and Grx5p; redundantly protects cells from oxidative damage along with GRX4 and GRX5; with Grx4p, promotes the dissociation of Aft1p from iron regulon gene promoters and subsequent nuclear export in iron-replete conditions, regulating iron homeostasis; involved with Grx4p in the deglutathionylation of Sir2p, restoring deacetylase activity after disulfide stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>GRX3 YDR098C
ATGCCTGTTATTGAAATTAACGATCAAGAGCAATTTACTTACCTAACTACCACTGCGGCC
GGCGACAAGTTAATCGTGCTTTATTTCCATACCAGTTGGGCAGAACCATGCAAAGCATTA
AAGCAGGTTTTTGAGGCCATTAGTAATGAGCCTTCCAATTCCAACGTCTCTTTCTTATCC
ATTGATGCGGACGAAAACTCGGAAATTTCAGAACTTTTTGAAATCTCAGCTGTTCCATAT
TTTATCATAATTCACAAAGGGACAATCTTAAAAGAATTATCCGGCGCGGATCCAAAGGAG
TATGTGTCTTTATTAGAAGACTGCAAGAACTCAGTCAATTCCGGATCATCACAAACTCAT
ACTATGGAAAATGCAAACGTAAATGAGGGGAGTCATAATGATGAAGACGATGACGACGAA
GAAGAGGAAGAAGAAACTGAGGAGCAAATAAACGCTAGATTGACTAAATTGGTCAATGCC
GCGCCGGTAATGTTATTTATGAAGGGGAGCCCCTCTGAACCTAAATGCGGGTTTTCGAGA
CAACTTGTGGGTATCTTGAGAGAACATCAAGTAAGATTTGGCTTCTTTGATATATTAAGA
GACGAATCTGTTAGACAAAACTTGAAAAAGTTTTCTGAATGGCCAACTTTCCCTCAACTT
TATATAAATGGGGAGTTTCAAGGCGGTTTAGACATTATCAAGGAATCCTTGGAGGAAGAC
CCTGATTTTTTGCAGCATGCTCTCCAATCTTAA
Promoter Sequence
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>GRX3 YDR098C
CATTGCTGATGTGATGACAAAACCTCTTCCGATAAAAACATTTAAACTATTAACAAACAA
ATGGATTCATTAGATCTATTACATTATGGGTGGTATGTTGGAATAAAAATCAACTATCAT
CTACTAACTAGTATTTACGTTACTAGTATATTATCATATACGGTGTTAGAAGATGACGCA
AATGATGAGAAATAGTCATCTAAATTAGTGGAAGCTGAAACGCAAGGATTGATAATGTAA
TAGGATCAATGAATATTAACATATAAAACGATGATAATAATATTTATAGAATTGTGTAGA
ATTGCAGATTCCCTTTTATGGATTCCTAAATCCTCGAGGAGAACTTCTAGTATATTCTGT
ATACCTAATATTATAGCCTTTATCAACAATGGAATCCCAACAATTATCTAATTACCCACA
TATATCTCAATAACAAAACGAACAACATGAGATAAAACACGGCCTTCCCTAGCTGAACTA
CCCAAACGTATAAATGCTTGAACAATTAGTTTAGATCCGAGATTCCGCGCTTCCACCACT
TAGTATGATTCATATTTTATATAATATATAAGATAAGTGACATTCCGTGAATTAATCTGA
TAAACTGTTTTGACAACTGGTTACTTCCCTAAGACTGTTTATATTAGGATTGTCAAGACA
CTGCGGTATTACTCGAGCCCGTAATACAACAATACACAGTTGTTACGGTCCTATAGTGTA
GTGGTTATCACTTTCGGTTTTGATCCGGACAACCCCGGTTCGAATCCGGGTAGGACCTTT
TTTAACTGTGGCTTCTCTGTTGAACCATCAGTTACTTTTTTTTTTTTTCAGAGAATGTGT
GCCGGGTCATGAGATGCCAAACTAAGAGGTCATTAAAATATATTTCAAAGACTAAATGTG
TTCTTTTCAGGTTCCATCTGCATTTTCTTTTAACTACACCTCGTACTGTTATAAACGCCA
CCAAGCAAGATATTACACAGCAGCAAAACTTTTTCAGGAA
Chr coordinates
Chr IV from 644930-644178