Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
STE5 Systematic Name
YDR103W Alias
HMD3, NUL3 Strain
S288c Description
Pheromone-responsive MAPK scaffold protein; couples activation of the G-protein-coupled pheromone receptor to MAPK activation; intramolecular interaction of PH and VWA domains blocks activation of assembled signaling cascade components (Ste11p, Ste7p and Fus3p) under basal conditions; Gbeta-gamma (Ste4p-Ste18p)-dependent docking at the plasma membrane and binding of PI(4,5)P2 by the PH domain relieves autoinhibition, resulting in pheromone-dependent pathway activation External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>STE5 YDR103W
ATGATGGAAACTCCTACAGACAATATAGTTTCCCCTTTTCACAATTTTGGTAGCTCGACA
CAATATAGTGGTACCTTGTCGAGAACTCCCAACCAAATAATAGAGCTAGAGAAGCCCAGT
ACTCTATCCCCATTGTCAAGAGGAAAAAAATGGACGGAAAAGTTAGCCAGGTTCCAAAGA
AGTAGTGCTAAAAAGAAAAGATTCTCACCTTCTCCTATTTCCTCCTCTACATTTTCGTTC
TCACCCAAATCTAGGGTCACTTCTTCAAACTCTTCTGGCAATGAAGACGGTAACCTAATG
AATACACCTTCTACGGTTTCCACTGATTATTTGCCACAACACCCTCACAGAACATCGTCT
TTGCCAAGACCTAATTCCAATCTCTTTCACGCAAGTAATAGTAACCTATCCCGAGCAAAT
GAGCCCCCAAGGGCCGAAAATTTATCAGATAATATACCACCCAAGGTCGCTCCATTTGGC
TATCCAATACAAAGAACCTCTATTAAAAAATCCTTTTTGAATGCTTCTTGTACGTTATGT
GACGAGCCTATTTCTAACAGAAGAAAGGGAGAGAAAATTATAGAGCTTGCATGTGGCCAC
TTAAGTCACCAAGAATGTCTTATTATCTCTTTTGGCACCACTTCAAAGGCAGACGTTCGT
GCGCTATTTCCTTTTTGTACCAAATGTAAAAAAGATACTAACAAAGCCGTTCAATGCATT
CCAGAAAATGATGAACTAAAGGATATTCTAATTTCTGATTTTTTGATTCATAAGATTCCT
GATTCTGAGTTATCAATCACACCTCAGTCCCGCTTTCCTCCTTATTCACCACTCTTGCCT
CCTTTTGGGTTATCCTATACACCTGTTGAAAGACAAACGATATATTCTCAAGCTCCAAGT
CTAAACCCAAATCTCATATTGGCTGCACCCCCCAAGGAAAGAAACCAAATTCCACAAAAA
AAATCAAACTATACATTTTTACATTCACCCCTGGGGCACAGAAGAATTCCGTCCGGAGCA
AACTCTATCTTAGCAGACACCTCTGTAGCGTTGTCAGCTAATGATTCTATTTCTGCTGTT
TCCAATTCGGTAAGAGCAAAGGATGACGAAACCAAAACAACGTTGCCGCTGTTAAGGTCA
TATTTTATTCAAATTCTTTTGAACAATTTCCAGGAAGAATTGCAGGATTGGAGAATAGAC
GGGGACTATGGATTACTAAGGTTGGTAGACAAATTGATGATTTCCAAAGATGGTCAGAGA
TATATACAATGCTGGTGTTTCTTATTTGAAGACGCATTTGTAATAGCAGAAGTGGATAAC
GATGTTGATGTTTTGGAAATTAGACTAAAGAATTTAGAAGTATTTACACCTATTGCCAAC
TTGAGAATGACTACACTCGAAGCTTCAGTACTCAAATGCACCTTAAATAAACAACATTGC
GCCGATTTATCAGATCTTTACATTGTTCAGAATATAAATTCTGACGAAAGCACAACTGTA
CAGAAATGGATATCAGGTATATTGAATCAGGATTTTGTATTCAATGAGGACAATATCACT
TCGACCCTGCCTATTCTTCCCATTATAAAGAACTTTTCAAAAGATGTTGGTAATGGTAGG
CACGAGACGAGTACCTTTCTAGGTTTAATCAATCCTAACAAAGTTGTTGAAGTTGGAAAT
GTGCACGATAATGATACTGTAATCATAAGGAGGGGATTCACCTTAAATTCAGGAGAATGT
TCTAGGCAGAGTACTGTCGACAGTATACAATCTGTTCTAACCACGATAAGCTCAATTCTT
TCCCTTAAACGAGAAAAACCTGATAATTTGGCAATAATCTTACAGATCGATTTTACGAAA
TTGAAGGAAGAAGACAGTTTAATTGTTGTTTATAACAGTCTAAAAGCTTTAACCATTAAA
TTTGCGCGTTTGCAGTTTTGTTTCGTTGATCGAAATAATTATGTTCTGGACTATGGATCG
GTATTACACAAGATAGATTCACTAGATTCCATCTCAAATCTCAAATCAAAGAGTTCCTCG
ACACAATTTTCACCTATTTGGTTGAAAAATACTCTATATCCCGAAAATATTCATGAACAT
TTGGGTATTGTTGCTGTATCAAATAGTAATATGGAAGCAAAAAAATCCATACTATTTCAA
GATTACAGATGCTTTACAAGTTTTGGAAGAAGAAGGCCCAATGAATTGAAGATTAAGGTG
GGCTATTTGAACGTTGACTACAGTGATAAAATTGATGAACTAGTCGAGGCCAGCTCCTGG
ACTTTTGTTTTAGAAACTCTTTGCTACAGTTTCGGTCTAAGTTTTGATGAACATGATGAC
GATGACGAAGAGGATAATGATGATTCGACCGATAATGAACTTGATAATAGTTCAGGATCA
CTGTCGGATGCTGAATCTACAACTACTATTCATATTGATTCTCCATTTGATAATGAAAAT
GCTACCGCAAATATGGTGAATGACAGAAACCTTCTCACTGAGGGTGAACATAGCAATATA
GAAAACTTAGAAACTGTCGCTTCTTCAGTACAGCCAGCTCTGATTCCTAATATTAGATTT
TCACTTCATTCTGAGGAGGAAGGTACTAATGAAAATGAAAATGAAAATGATATGCCAGTA
TTATTACTTAGTGATATGGATAAAGGAATCGATGGCATAACCAGACGCAGTTCATTCTCG
AGTCTTATAGAGAGCGGTAATAACAACTGTCCCCTCCATATGGATTATATATAG Promoter Sequence
Download FASTA
>STE5 YDR103W
TCAAAGCAGTTTGTGCGATTTGTCCAGCAGTTCTGTATTTGTTCAAGACCGATTCCTGTA
GAATATTTTTGTCCTTTAGCAAAATCTGAGTATCCTCGTGGGAGATAGCTAGAGCCATGA
TAGTTTTAGCAATATTAGTCGGGTCGGGTTTTTTCTTAAAAGTATTTTGAATAACACGAT
GCTTTAGCTCATCTCATCTCTTCTGCTGAAATTTTTCTTTACTTCGGTAAAATTTTTTCA
GAAAGCAAAAAAAGCTTCACAGAGGCATGACCCTCTCCGGGTAAAAAAAAGCTTAGGGTT
ACCGGCCTGTCATTTTTAGGGCATTATCAATTTTTTGCCATCTAGTTGCAACTATAATAA
TACAGTATGAATTGCACGAAAGAGCAGTCAATGTAAATTCACGAAGTGACTGACAGAATA
CTGACATCAGCTGATTTCTCATAGAGCTGTTTCTCTGATAACACGTTGTTTGAACATCGA
CAAGATGAAAATCTAGAAGTATCAAGTTTCCTTTAAAGGGATATATAACAGATTCTAAAA
CTGACAGAAATATTTCGAGTGAAGAAGAAGCGTTAAATATTGGATCTTTCCGCAGTTCTA
CTCTGATACATTTTTGAAGTAGGAGAGTCATTTAGAAGGCGTATTGCTCAATAGTAGAAA
GCAGGCCTGTGCACATGAATTAATTAAAAAATATAAAGGTAGTGATTAGACGACACATGT
CCATAGGTAACCTGTCATAATTTTGAACAATTTCCCTTCTTTTCTTTTTTTTTTTTGGGT
GCGGCGATATGTAGCTTGTTAATTTACACATCATGTACTTTTCTGCATCAAAATATGAAA
GGCGATAGTAGCTAAAGAAAATACCGAGAATTTCCTCGAAAAGTTGACGACAAAAGAAAG
GCATAAAAAAGTAATTTGAAAATATTTTAAAACTGTTTTAACCCATCTAGCATCCGCGCT
AAAAAAGGAAGATACAGGATACAGCGGAAACAACTTTTAA
Chr coordinates
Chr IV from 658350-661103
