Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SAC6 Systematic Name
YDR129C Alias
ABP67, fimbrin Strain
S288c Description
Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SAC6 YDR129C
ATGAATATTGTCAAATTACAAAGAAAATTTCCAATTTTGACTCAAGAGGATCTTTTTTCC
ACAATTGAAAAGTTCAGAGCCATTGACTTAGATGATAAAGGATGGGTTGAAAAACAGCAA
GCTCTAGAAGCGGTGTCCAAAGATGGTGATGCTACTTATGACGAAGCAAGAGAAACCCTG
AAGCATGTGGGTGTGGATGCGTCAGGCCGTGTTGAACTGGACGATTACGTCGGGTTGGTT
GCAAAATTAAGAGAATCTAAAACAGGAGCTGCTCCACAGACCACTTTCAACGTAGCACCT
AACTCAACCCCTATTGTTTCCACTGCTGCCACAGGACTACAGCACAAGGGTAAGGGTACT
CAAGCCAAGATTATTGTTGCTGGCTCCCAAACAGGTACTACACATACCATCAATGAAGAA
GAAAGACGTGAATTTACTAAACATATCAATAGCGTCTTGGCGGGAGACCAAGATATAGGT
GATTTGCTTCCATTTCCTACTGATACTTTCCAATTATTTGATGAATGTAGGGATGGGTTG
GTGCTATCTAAGTTGATCAACGACTCTGTTCCTGATACTATCGATACAAGAGTTTTGAAT
TGGCCTAAGAAGGGTAAGGAATTGAATAATTTTCAGGCTAGTGAAAATGCTAATATTGTT
ATTAATTCTGCAAAAGCCATTGGTTGTGTCGTTGTTAATGTTCATTCCGAGGACATTATT
GAAGGTAGAGAGCATTTGATCCTGGGTTTGATTTGGCAAATTATTAGGAGAGGTTTGTTA
AGTAAAATTGATATTAAGCTGCATCCTGAGTTATACCGTCTATTGGAGGATGATGAAACG
TTGGAGCAATTTTTGAGGTTGCCTCCGGAGCAAATTCTACTACGTTGGTTTAACTACCAT
TTGAAGCAAGCAAACTGGAACAGAAGGGTTACCAATTTTTCAAAAGACGTGTCTGATGGT
GAAAACTATACTATCTTGTTGAACCAGTTGGACCCCGCCTTGTGTTCTAAGGCACCATTA
CAAACCACAGATTTAATGGAGAGAGCTGAGCAAGTTTTACAAAATGCTGAAAAGCTAGAT
TGTAGAAAGTATTTAACCCCAAGTTCATTAGTTGCGGGGAACCCTAAATTAAACCTGGCT
TTCGTGGCACATCTATTCAATACACATCCTGGATTAGAGCCTATTCAGGAAGAGGAAAAG
CCTGAAATTGAAGAATTTGACGCCGAAGGTGAGAGAGAGGCAAGAGTCTTTACCTTATGG
TTGAACTCTCTTGACGTTGATCCACCTGTCATTTCGCTGTTTGATGATTTGAAGGATGGT
TTGATATTATTGCAAGCTTACGAAAAGGTGATGCCCGGTGCTGTTGATTTTAAACATGTC
AACAAAAGACCGGCCTCGGGTGCAGAGATATCCAGATTCAAAGCCTTAGAAAACACCAAC
TATGCAGTCGACTTGGGCAGAGCCAAAGGATTTTCTTTGGTTGGTATCGAAGGATCTGAT
ATTGTAGATGGTAACAAATTACTGACCTTAGGGTTAGTGTGGCAATTGATGCGTAGAAAT
ATTTCGATAACCATGAAGACATTATCCTCAAGTGGTAGAGACATGAGTGATTCTCAAATA
TTAAAGTGGGCCCAAGACCAGGTAACTAAAGGTGGTAAAAACTCTACCATTAGATCATTT
AAGGACCAAGCTTTATCAAACGCCCACTTCTTATTGGATGTTCTGAATGGTATCGCGCCG
GGCTATGTTGATTATGATCTAGTCACCCCTGGTAACACCGAGGAAGAAAGGTACGCAAAC
GCAAGATTGGCTATTTCTATTGCTAGAAAGTTGGGTGCTTTGATTTGGTTGGTGCCAGAA
GATATCAACGAAGTTCGTGCAAGATTAATTATTACTTTTATCGCTTCGTTAATGACTTTG
AACAAATGA Promoter Sequence
Download FASTA
>SAC6 YDR129C
GTCTCTAAGGAAACTCAAAGCCTGGATAGGCCTCAGTTCAAAAATTCGAATAAAAATGTG
AAGATCCAAAACTCAGATCATATAACTAATATAATATTCCCTACATCACCAACCAAACTG
ACATTCAGTAATGAAAATAAAATCGGGGGTGATGGTTCGTTAACGAGAATACGGGCCCGG
TTTAAGAATGGACTCATGTCACCTGAAAGGATACAGCAGCAACAGCAGCAACATATTCTC
CCATCGGATGCCAAAAGCAACACTGACCTCTGTTCTAATACTGAGCTCAAGGACGCCCCA
TTTGAGAATGACCTTCCTCGAGCTAAATTGAAAGGGAAGAATTTATTAGTTGAACTCAAG
AAAGAAGAGGAAGACGTGGGAAATGGCATAGAATCCCTTACTAAATCGAACACTAAACTG
AATTCCATGCTGGCGAACGAAGGTAAGATACACAAAGCTAGTTTCCAGAAAAGTGTAAAA
TTTAAACTACCTGATAATATAGTGACTGAAGAAACCGTGGAACTTAAAGAAATAAAGGAC
TTGCTACTACAAATGTTGAGAAGACAGCGAGAGATTGAATCAAGATTATCCAATATCGAA
CTTCAACTCACGGAAATACCGAAACATAAGTAATCATATCCCTTCTCACATTTTTTACAC
AGGAAGTAAGCAAGTTATGTTATATTTCCGACACTATAATTAATTCTTAGCAGTTAAAGG
TGCTTTGTCTATATTACATTTACATACAGCTTGAGTGATCCTGACCGGATATAGGGTCCT
ATTTTCTTACGTGAACGGCTTTTCTTCTTGTTCCCGATGGCCTTCATGTGAAAAAGCACT
CCTCGGGAGGCGGAAAAATATCAAAAGTACGGGGCGAAGTTTATAATGAAGATTTATCGA
TATAAATTTTGGTTATTTCAGGAGAACAAGAAAGCTCTTTACACTAAAATTATCAGAGAA
GAAGCTGATATATTAGCCCTAAGGAGTACACCAAAACACA
Chr coordinates
Chr IV from 715247-713340,715379-715359
