Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SCC2 Systematic Name
YDR180W Strain
S288c Description
Subunit of cohesin loading factor (Scc2p-Scc4p); a complex required for loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX; promotes gene expression program that supports translational fidelity; evolutionarily-conserved adherin; relocalizes to cytosol in response to hypoxia; human disorder Cornelia de Lange syndrome is caused by mutations in NIPBL, the human ortholog of SCC2; conserved role in NHEJ External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>SCC2 YDR180W
ATGTCGTACCCAGGGAAAGACAAGAATATTCCTGGAAGAATAATAGAGGCCCTAGAAGAC
CTGCCTTTGAGTTATCTGGTTCCTAAGGATGGGTTAGCCGCGCTAGTAAATGCCCCAATG
CGGGTTTCTTTACCTTTTGACAAGACTATCTTTACCAGCGCTGATGATGGCAGAGATGTT
AATATAAATGTTCTAGGTACAGCTAACAGCACTACTTCTTCCATAAAGAATGAGGCCGAA
AAAGAAAGGCTTGTTTTCAAAAGACCCAGTAATTTTACGTCATCAGCCAATTCTGTTGAT
TATGTCCCAACTAACTTTTTGGAAGGATTATCACCGCTAGCGCAGAGTGTTCTATCAACC
CATAAAGGGTTGAATGATTCCATTAACATCGAGAAAAAAAGTGAAATAGTAAGCAGACCG
GAGGCAAAGCATAAGCTCGAAAGTGTGACTTCGAATGCTGGTAACTTGAGTTTCAACGAC
AATTCTTCCAACAAGAAAACCAAAACTTCAACAGGTGTAACCATGACACAAGCGAATTTA
GCGGAACAATATTTGAATGATCTTAAAAATATTTTAGATATTGTTGGATTTGACCAAAAC
TCTGCTGAAATTGGAAATATCGAGTACTGGCTCCAGTTGCCAAATAAAAAATTCGTTTTA
ACTACAAACTGCTTAACCAAATTACAAATGACAATTAAAAATATTACCGATAACCCACAG
CTATCGAACTCAATCGAAATAACATGGCTTTTGAGATTGCTTGATGTGATGGTTTGTAAT
ATAAAGTTCAGTAAAAGCTCTTTAAAGATGGGTTTAGATGATTCTATGTTACGATATATT
GCTTTGCTTTCTACAATTGTACTATTCAATATTTTTTTACTGGGTAAGAATGACAGCAAC
TTACATCGGGAATCATACATCATGGAACCGGTGAATTTTTTAAGCGACTTGATAGAATCT
CTAAAAATATTAACAATTGAATATGGTTCTTTGAAGATAGAATTTGACACTTTCCAGGAG
GCCCTAGAATTGCTACCGAAATACATACGTAACGGCCCTTTTCTGGATGATAATGTCACG
GCAAAGCTTGTGTACATCTTTAGCGACTTGCTGATGAATAATGACATTGAAGCAACTACG
AATATCCAATTTCAAAGTTTTTGGGATAATGTGAAGAGAATCAGCTCTGATATTTTAGTT
TCATTATTCGGTAGTTTTGATCAACAGAGAGGATTTATTATAGAAGAACTACTATCTCAT
ATCGAAAAGCTTCCCACTAAGAGAATACAAAAAAAACTAAGAAAAGTTGGTAACCAAAAC
ATTTATATCACTGATTTTACCTTTACTTTAATGTCAATGTTAGAGAATATTAATTGCTAC
TCCTTCTGTAATCAGATGAAGGATATTGCACCAGAGAATATTGATCTATTAAAGAACGAA
TACAAAAAGCAAGAAGAATTTCTTTTTAACATTGTTGAGCATATAAATGACACAATACTG
GAAAGGTTTTTCAAGAACCCGTCCGCTTTAAGGTATGTAATTGACAACTTTGTCCAAGAT
CTATTATTGCTAATTTCCTCCCCTCAGTGGCCTGTAACAGAAAAAATACTAAGCTCTTTG
TTAAAGAGACTTCTAAGTGTATACAGCCCATCCATGCAAGTTTCTGCAAACATTGAAACA
ATATGTTTACAACTTATAGGGAATATTGGTTCTACAATTTTTGATATTAAATGCTCAACT
AGAGACCATGAAGATAACAACTTGATTAAAATGATTAATTACCCCGAAACTTTGCCGCAT
TTTTTTAAATCATTTGAAGAATGCATTGCATATAATGAAACGATCAAATGCCGTCGTTCT
GCAACAAGATTCCTTTGGAATTTAAGGCTCGGTACGATCTTGATATTAGAAGAGTATACA
AAGGATGCCAAAGAACAAATTATAACCGTTGACAATGAATTGAAAAAAATATTGGAGCAG
ATAAAAGATGGTGGACTTGGACCCGAATTAGAGAACAGAGAAGCAGATTTTAGTACGATT
AAATTGGATTATTTTTCTATTTTGCACGCCTTTGAACTACTGAATCTATACGATCCATAC
TTGAAGTTGATATTATCACTTCTAGCCAAGGATAAAATCAAACTGAGATCGACTGCTATT
AAATGTCTCTCGATGTTGGCTTCAAAAGACAAAGTGATACTTTCAAACCCAATGGTTAAA
GAAACTATTCACCGGCGTTTAAACGACTCATCTGCATCTGTCAAGGATGCCATTCTAGAT
TTGGTCAGTATTAATTCTTCATACTTCGAATTTTATCAACAAATTAACAACAACTATAAC
GATGATAGCATAATGGTAAGAAAACATGTGTTAAGAATTAATGAAAAAATGTACGACGAG
ACGAACGACATCGTCACGAAGGTATACGTAATAGCAAGAATCCTAATGAAAATAGAAGAC
GAGGAGGACAATATAATTGATATGGCTAGGCTGATTTTATTAAATAGATGGATATTAAAG
GTACATGAAGTATTGGACCAGCCCGAAAAGTTGAAAGAAATTTCTTCTTCAGTCCTACTA
GTAATGTCCCGTGTGGCTATAATGAATGAGAAATGCTCCCAACTTTTCGACTTGTTTCTC
AACTTTTATCTCCTAAACAAAGAAGCGCATTCAAAAGAAGCATACGATAAAATCACTCAC
GTTCTAACCATTCTTACCGACTTTTTGGTACAAAAAATTGTCGAGCTCAACTCAGATGAC
ACAAATGAAAAGAATTCGATTGTTGATAAACAAAATTTTTTAAACCTTTTGGCGAAGTTT
GCTGATTCTACTGTGTCATTTTTGACTAAAGACCACATTACAGCATTGTATCCTTATATG
GTATCGGACGAAAAATCTGACTTCCACTATTATATCTTGCAAGTCTTTAGATGCACTTTT
GAAAAATTGGCCAACTTTAAACAGAAATTTTTGTATGACTTAGAGACGACCCTTTTGAGT
AGGCTACCAAAGATGAATGTAAGAGAGATAGATGAAGCTATGCCTCTTATCTGGTCTGTT
GCCACTCATCGTCATGATACTGCTAGAGTAGCTAAAGCATGTTCATCCTGTCTTTCCCAT
TTACATCCATATATAAATAAGGCAAATAACGAGGAAGCTGCCATTGTAGTTGACGGAAAA
TTGCAAAGGCTGATATATTTATCCACCGGTTTTGCCAGGTTCTGCTTTCCTAAACCCTCC
AATGATAAAATTGCATTTTTACAAGAAGGTGAAACCCTGTATGAACATATTACCAAATGC
CTACTTGTACTATCTAAAGACAAAATTACACACGTAATAAGAAGGGTTGCTGTGAAAAAT
CTCACTAAATTATGTGGAAATCATCCAAAACTATTCAATTCAAGACACGTTCTACATTTA
CTGGACAAAGAATTTCAGAGCGATCAGCTAGATATTAAACTAGTAATTCTAGAAAGTTTA
TATGATCTTTTTCTACTGGAAGAAAGGAAGTCAGTGAGAAACACTGGCGTTAATAGCACT
TTGTCTTCGAACTCCATTTTGAAAAAGAAATTACTGAAAACGAATAGGGTAGAGTTTGCA
AATGATGGAGTATGTTCAGCGTTGGCTACTAGATTTTTAGACAATATTCTCCAACTATGT
CTCCTACGTGATCTAAAGAATTCTCTCGTAGCTATTCGATTATTAAAGTTGATTTTGAAA
TTTGGTTACACAAATCCCTCTCATTCAATTCCAACTGTAATTGCTTTATTTGCCTCTACT
AGCCAGTATATTCGTCATGTCGCCTATGAGTTGTTAGAAGATCTTTTTGAGAAATACGAA
ACGCTAGTATTCAGTAGTTTATCTCGAGGGGTTACAAAAGCTATACATTATTCTATTCAT
ACAGATGAGAAGTATTATTACAAGCACGATCATTTTTTGTCTTTACTTGAAAAATTATGT
GGAACTGGAAAAAAAAATGGCCCAAAGTTCTTTAAAGTTCTGAAGAGAATCATGCAATCC
TATTTAGATGATATCACCGATTTAACATCAACAAATAGTAGTGTTCAAAAGTCCATTTTC
GTTCTCTGCACTAACATTTCGAATATCACATTTGTTTCTCAGTACGATTTGGTGTCCCTA
CTCAAAACCATTGATTTAACTACAGATAGATTAAAAGAGGTTATCATGGATGAAATAGGT
GACAATGTTTCATCGCTATCCGTATCAGAAGAAAAGCTCAGTGGAATAATTTTAATACAG
TTAAGCTTACAGGATTTGGGTACTTATCTACTGCACTTATACGGGTTAAGGGATGATGTG
CTTTTATTAGATATTGTAGAAGAATCAGAATTGAAGAACAAACAACTCCCTGCAAAGAAG
CCGGATATCAGTAAGTTTTCCGCACAGTTGGAGAATATTGAACAGTATTCATCAAATGGC
AAGCTTCTTACATATTTTAGAAAACACGTGAAGGATACGTAA Promoter Sequence
Download FASTA
>SCC2 YDR180W
TTTTAGCTTATTCAACTTCAACAGAAGCAGCAAATATGAACACTGCCGAAATTCAAGAAA
CAGCATTTCTACAAAGATATATTTTTACTTTTTTCACCGATGATTTTTTCAAATTATCTA
TGAGGAAGCCATTCCTATTCTCAATATGCAGAACGCTTCAGCATTGGATCTCTAAATTAA
ATGCGTTAAACAGGGTCATGTATAGAACATTTGACAATATTGTTCAAACTAAAATTACCA
GCCCTGTGACAATTGGCAACTTATTCTCATTATTACGACATTCTTTGTTTCCTAATGACA
ATATGATGGGGCCACCAAGAGTATTACCAGTGGGTGATGCTTTTCTAGAGTTCAGAGAAG
AGTGTATTTCCAATTTATGGGATGTTTGTATGACTTATAAACTTGATCATATCCTCGCTA
TCAAAAGGTCTGACATAGCGGATCTTATTATCTGCATATCGAAGAATAGGGATTGCAATA
AACTGCTAATTTATAGAATTATTGACTGTGTTATTGCGCAGTTGCCGTAGACTTCGTGAT
GTATAGAGTATTGTTGACAAATATTTGATGTTACCGAAATAGCACTCTTTGTAGCATTAT
TACCAATTTTTATACTATGAAGTAAGGTCTTAGGAAGCAAGAACATTGTTAACAAATAGC
TTTTATGACCTAATCATTAGCACTATTCATTGCCAAATATGCAAATATCTATTCCTTTTG
CCCGAACAGGTAAAAGTGGTATTGCTTTTATGTTAAACGCGAAACTGCCGCCACTTCGCT
TAAAAAAAACACTGGCTGAAAAAGAACGATGCAGTTTAGTAACTAAAGTTTTTTCTAGCT
CAGGCTTAGAGTTCGATAACAACAAGTCACATTCGAGTGCTCCACTTATAGCAATTTTTC
TTTTGTGTATTGGTTTGCTCCTGTGTGCTCAGGCTTTTCGTTTGTTGTGAGAGTATTGTT
CTTATAACTATTCATTTTTTGAAAGAATTGGCGGCTAGCA
Chr coordinates
Chr IV from 821295-825776
