Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
UME6
Systematic Name
YDR207C
Alias
CAR80, NIM2, RIM16
Strain
S288c
Description
Rpd3L histone deacetylase complex subunit; key transcriptional regulator of early meiotic genes; involved in chromatin remodeling and transcriptional repression via DNA looping; binds URS1 upstream regulatory sequence, represses transcription by recruiting conserved histone deacetylase Rpd3p (through co-repressor Sin3p) and chromatin-remodeling factor Isw2p; couples metabolic responses to nutritional cues with initiation and progression of meiosis
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>UME6 YDR207C
ATGCTAGACAAGGCGCGCTCTCAAAGCAAACACATGGACGAATCTAATGCGGCTGCCTCT
CTGCTTTCGATGGAAACAACCGCCAACAATCATCACTATTTGCACAATAAAACATCTCGT
GCCACGCTGATGAATAGCAGCCAAGACGGCAAAAAACATGCAGAAGATGAAGTTAGTGAT
GGAGCTAACTCCCGCCATCCTACAATTTCCAGTGCTAGCATCGAATCTCTCAAGACAACC
TACGATGAAAACCCTTTGCTTTCTATTATGAAATCGACATGTGCGCCCAACAACACTCCC
GTGCATACTCCGTCTGGTTCGCCGAGTTTGAAAGTCCAAAGTGGCGGAGATATCAAAGAC
GATCCTAAGGAAAACGATACTACTACTACGACCAATACTACACTTCAAGATCGCCGTGAC
AGCGATAACGCTGTGCATGCTGCCGCCAGCCCACTCGCGCCTTCCAATACACCTTCGGAT
CCTAAGTCATTGTGCAATGGCCATGTCGCACAGGCTACAGACCCACAAATTTCCGGTGCT
ATTCAGCCGCAGTATACTGCAACCAACGAGGATGTTTTCCCTTACTCCTCCACCTCCACT
AATAGTAACACTGCCACTACTACTATCGTCGCCGGCGCCAAAAAAAAAATACATTTGCCG
CCACCACAAGCTCCAGCGGTTTCTTCCCCCGGTACCACCGCAGCAGGCTCGGGCGCGGGC
ACGGGCTCGGGCATCCGTTCCCGCACAGGATCGGATTTGCCGCTCATCATTACCAGCGCC
AACAAGAACAACGGTAAGACTACCAATTCGCCTATGTCGATACTGAGCAGAAACAACAGT
ACCAACAACAACGACAATAATTCGATACAAAGCTCAGATTCGAGAGAATCCTCTAATAAC
AATGAGATTGGCGGGTATTTGCGCGGCGGAACTAAGCGCGGCGGCAGTCCATCTAACGAC
TCTCAGGTCCAGCATAATGTGCATGATGACCAATGTGCCGTGGGCGTGGCGCCCAGGAAC
TTCTATTTCAACAAGGATAGAGAGATAACAGACCCAAATGTAAAACTGGACGAGAACGAA
TCAAAAATCAACATATCGTTCTGGCTAAATTCGAAATACAGAGATGAGGCTTATTCTTTG
AATGAATCATCCTCCAACAATGCTAGTTCAAACACGGATACGCCTACAAACTCTCGACAT
GCGAACACCAGCTCTTCCATTACCAGCAGAAACAATTTCCAGCATTTTAGGTTCAACCAA
ATACCTTCTCAACCTCCAACTTCCGCATCTTCGTTTACAAGCACAAACAACAACAACCCT
CAACGGAACAATATCAATCGCGGTGAAGACCCGTTTGCCACTTCGTCAAGACCTTCTACT
GGGTTTTTTTACGGCGATTTGCCGAATCGTAACAATAGAAATAGTCCCTTCCATACAAAT
GAACAATACATCCCACCACCTCCACCGAAATACATCAATTCTAAATTGGATGGATTGAGA
TCAAGATTATTGCTCGGTCCGAATTCTGCATCTTCATCTACCAAACTAGACGACGACTTG
GGTACAGCAGCAGCAGTGCTATCAAACATGAGATCATCCCCATATAGAACTCATGATAAA
CCCATTTCCAATGTCAATGACATGAATAACACAAATGCGCTCGGTGTGCCGGCTAGTAGG
CCTCATTCGTCATCTTTTCCATCAAAGGGTGTCTTAAGACCAATTCTGTTACGTATCCAT
AATTCCGAACAACAACCCATTTTCGAAAGCAACAATTCTACAGCTGTTTTTGATGAAGAC
CAGGACCAAAATCAAGACTTGTCTCCTTACCATTTAAATCTAAACTCTAAAAAGGTTTTA
GATCCCACTTTTGAGTCAAGGACAAGGCAAGTTACTTGGAATAAGAATGGTAAGCGAATA
GACAGACGCCTTTCTGCTCCAGAACAACAACAGCAACTGGAAGTTCCACCATTGAAAAAA
TCGAGAAGGTCAGTTGGAAACGCAAGAGTAGCAAGCCAAACCAATAGCGATTATAATTCT
CTTGGCGAATCCTCAACTTCGTCAGCTCCATCGTCTCCATCTTTGAAGGCTTCTTCTGGC
TTGGCATATACCGCTGATTATCCTAACGCTACTTCGCCGGATTTCGCTAAATCTAAAGGA
AAAAATGTCAAGCCTAAGGCAAAATCAAAGGCGAAACAGTCATCAAAGAAAAGACCAAAT
AATACTACTTCGAAATCAAAAGCAAACAATTCTCAAGAATCGAATAATGCTACTTCCTCA
ACGTCTCAAGGTACAAGGTCCCGTACTGGTTGCTGGATTTGTAGATTAAGGAAAAAGAAG
TGTACCGAGGAAAGACCGCACTGTTTCAACTGTGAAAGGTTGAAATTGGACTGTCACTAT
GACGCGTTCAAACCAGATTTTGTATCTGATCCAAAGAAAAAACAGATGAAACTGGAGGAA
ATCAAGAAAAAAACAAAAGAGGCCAAAAGAAGAGCAATGAAAAAAAAATAA
Promoter Sequence
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>UME6 YDR207C
ATTGTTGGGTTTAACTCTTCAATAGAGGTCGGAGTGGAAGACTCACCATCTGACAAGCGA
GGACTTTCCATGTTTGACTCCGAATTCGATGAAGAATGGTAGCTAGTGTGATTATTGCGA
TCCTTTTTTATTCGATGGTTCGAATCCGGATTCGAATTCGAATTCGGCACCGAACGGTCT
TGATGTCGCTCAATTATTGCAGAGTGCAATAGCGATGGTTCCTGTTCTGTTTTGCGACTG
GTGGATGTTGTCAGATGTAGCGGTACAACTGAAGGAGGTTGTGATCGCAAGACTGACATG
AGTTAGAAACTATTGATAGGGAAAAGCGATATAGGGCAACTGTCTCGGGGGGTGTAAACA
GGTTTCGTACTCTCTTGCTTATGAATGTGCTACTTCTTGTTCCTATTTTTTGTTTCTGTC
CTTGTTTTTTCTTTGCTTGTCCCTCCGTATTTGCTTCTTTGTTGTCACGCTTTTGTTATT
TCCACCTCTATCTTTCCTCTCTGTCCCATTCCCCATCCATTCCTTTCTTTTTTTTTTTAA
CCTGTGTTTTGTTTTCCCAGAATGGGCGGCACGTTCTTATGTCCGTAAAAACGGATATAC
AAAAGCGACACGTCGTCTGAGGTGACACTCCACTCAACCCCACTTGCCCAAAACATGCAT
TGCTACAAGTAGTAGAGCGCAGTTTTTAAAGTCCATTGGTTGCACACGAAATCACGAGAA
TAATCACGAGAATAGAATGCACGTTGGATTTCGGGCATCCTATAATTGCCAAGACTGCGC
TACTTCTCTTCTGTTTCGGTCCGGGTGACACGTCCGCCGTGCTTCAAGGCGCCTTTTCAC
CAATGCCAGGCGGAAACTGCCGCCGTCAAAAAGAAAAATGAAAAGAACATAGAGGACAAG
GACAAGAGACCAGTGATCGTAAGAAGCGCCCACCTTCGCACAGCGCACAGGAACTAGGAC
ACTACCGCACTCAAACCATTTGCATGGACCTTAACTCACG
Chr coordinates
Chr IV from 867522-865012