Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
GCD6 Systematic Name
YDR211W Strain
S288c Description
Catalytic epsilon subunit of the translation initiation factor eIF2B; eIF2B is the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; mutations in human ortholog cause fatal brain disease childhood ataxia with central nervous system hypomyelination (CACH); forms cytoplasmic foci upon DNA replication stress External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden Promoter Sequence
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>GCD6 YDR211W
GGGGTTCTCTGGAACAGCTGATGAAGCAGGTGTTGTTGTCTGTTGAGAGTTAGCCTTAGT
GGAAGCCTTATCATATTCTTGAATTTTGGAAGCTGAAACGTCTAACGGATCTTGATTTGT
GTGGACTTCCTTAGAAGTAACCGAAGCACAGGCGCTACCATGAGATATATGTGGGTAATT
AGATAATTGTTGGGATTCCATTGTTGATAAAGGCTATAATATTAGGTATACAGAATATAC
TAGAAGTTCTCCTCGAGGATTTAGGAATCCATAAAAGGGAATCTGCAATTCTACACAATT
CTATAAATATTATTATCATCGTTTTATATGTTAATATTCATTGATCCTATTACATTATCA
ATCCTTGCGTTTCAGCTTCCACTAATTTAGATGACTATTTCTCATCATTTGCGTCATCTT
CTAACACCGTATATGATAATATACTAGTAACGTAAATACTAGTTAGTAGATGATAGTTGA
TTTTTATTCCAACAATGGCCTCTTTAACACTAATATCCCGACAATTTTCCCAAAATTCAA
AGAATTCTCAGAAAGAGCTATTTTTTTTTTTAATAAAATTATTAGTACTAATTCCAGTAT
AAATAACAATGTTATTTACGTCTCTTTCGAAAATGCTCGTGTAGCTCAGTGGTTAGAGCT
TCGTGCTTATAGCAACATTCGGTTTCCGAAGTTTCTGTGCCAAAGACCTTTCAAACAGGC
CTTTAAAAGCAACGCGACCGTCGTGGGTTCAAACCCCACCTCGAGCACTTTCTCTTTTTT
TTTCACACGCGTTTGCAACATGCCCGTATTACATGAGCTTATTTGACTTTAGATGGTTTT
CAGTTCTTTTTTTTTTTTTTTTTTTTTTCAGTAGATTAATGCGAAGAGTTAAATCACCAA
TTCAAAGATGGCAGATGGACCACCTTGTGGGATAAGTATAAAAATAACTAAAAGTGGTCT
TGTGTTAAAAATAGAATAGAAACCACTCATAAGGCAAAAG
Chr coordinates
Chr IV from 884727-886865
