Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
GCD6 Systematic Name
YDR211W Strain
S288c Description
Catalytic epsilon subunit of the translation initiation factor eIF2B; eIF2B is the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; mutations in human ortholog cause fatal brain disease childhood ataxia with central nervous system hypomyelination (CACH); forms cytoplasmic foci upon DNA replication stress External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>GCD6 YDR211W
ATGGCTGGAAAAAAGGGACAAAAGAAAAGTGGACTAGGCAACCATGGAAAGAACTCTGAT
ATGGATGTTGAAGATCGTCTCCAGGCCGTTGTCTTGACAGACTCTTATGAAACTAGGTTT
ATGCCACTGACAGCTGTCAAGCCAAGGTGTTTGCTGCCACTGGCTAACGTACCTCTCATT
GAATACACCTTAGAATTTTTGGCTAAGGCTGGCGTACATGAAGTTTTCTTAATTTGCTCT
TCTCATGCCAACCAAATTAATGACTATATTGAGAATTCTAAGTGGAACTTGCCTTGGTCT
CCATTTAAAATTACCACCATTATGTCTCCAGAAGCTAGATGTACGGGTGATGTTATGAGA
GATCTAGATAATAGAGGTATCATTACTGGAGATTTTATTTTAGTCAGTGGTGATGTATTG
ACTAACATCGATTTCAGCAAAATGCTAGAATTTCACAAAAAAATGCATTTGCAAGATAAA
GATCACATCTCGACAATGTGTTTGAGCAAAGCGAGTACCTATCCAAAAACAAGAACTATT
GAGCCTGCCGCATTTGTCTTAGACAAATCCACCAGTAGGTGTATTTATTACCAAGATTTA
CCATTACCAAGCTCTAGAGAGAAGACTTCCATTCAGATTGACCCAGAATTGTTGGATAAT
GTCGATGAATTTGTCATAAGGAATGACCTCATCGATTGTAGAATTGACATTTGTACATCT
CATGTACCTTTGATATTTCAAGAAAATTTTGACTACCAATCATTAAGGACAGACTTTGTT
AAAGGTGTCATTTCAAGCGATATATTGGGAAAGCATATATATGCCTATTTGACGGACGAA
TATGCTGTAAGAGTTGAAAGTTGGCAAACTTACGACACCATTTCTCAAGACTTTTTAGGT
AGATGGTGTTATCCCTTGGTCTTAGACTCTAACATACAGGACGATCAAACGTATTCTTAT
GAATCAAGACATATATACAAGGAAAAAGACGTTGTTTTGGCCCAATCCTGTAAAATTGGT
AAGTGCACTGCAATTGGATCAGGAACAAAAATCGGAGAGGGTACGAAAATTGAGAATTCC
GTGATTGGAAGGAACTGCCAAATCGGTGAAAATATTAGAATCAAGAACAGTTTCATTTGG
GATGACTGTATCATCGGAAATAACAGTATAATTGACCATTCATTAATTGCCTCTAATGCC
ACGTTAGGGAGTAATGTACGCCTAAATGATGGCTGTATAATTGGTTTCAACGTTAAAATT
GATGATAATATGGATTTAGATAGAAACACAAAAATATCTGCCAGTCCATTAAAAAATGCC
GGCTCAAGAATGTATGATAATGAAAGCAATGAGCAGTTTGACCAAGACCTTGATGATCAG
ACACTAGCCGTTTCTATTGTTGGAGATAAGGGTGTTGGTTATATTTACGAAAGCGAGGTG
TCTGACGATGAAGATAGTTCTACAGAAGCCTGCAAAGAAATAAACACTTTGAGTAACCAA
TTAGATGAGTTATACTTAAGTGACGATTCAATTTCTTCCGCCACTAAAAAGACAAAGAAA
AGAAGAACGATGTCTGTCAATAGTATATACACGGATAGAGAAGAAATTGATTCTGAATTT
GAGGACGAAGATTTTGAGAAAGAAGGTATTGCCACCGTGGAGCGTGCTATGGAAAACAAT
CATGATCTTGACACAGCATTATTAGAATTGAACACCTTGAGAATGAGTATGAACGTGACA
TATCATGAGGTGAGAATAGCAACAATAACTGCATTATTGAGAAGAGTTTACCACTTTATT
GCAACTCAAACATTAGGTCCCAAGGACGCTGTGGTGAAGGTTTTTAATCAGTGGGGACTG
TTGTTCAAGAGACAAGCCTTTGATGAAGAAGAGTATATTGATTTGATGAACATCATAATG
GAAAAAATTGTAGAACAGAGTTTTGACAAACCGGATTTGATTCTATTTAGTGCATTGGTT
TCTCTATACGATAATGACATAATTGAGGAGGATGTCATTTATAAATGGTGGGATAATGTT
TCTACTGACCCTCGCTATGATGAAGTCAAGAAATTAACTGTAAAGTGGGTTGAGTGGTTA
CAGAATGCTGACGAAGAATCTTCCTCAGAAGAGGAATAA Promoter Sequence
Download FASTA
>GCD6 YDR211W
GGGGTTCTCTGGAACAGCTGATGAAGCAGGTGTTGTTGTCTGTTGAGAGTTAGCCTTAGT
GGAAGCCTTATCATATTCTTGAATTTTGGAAGCTGAAACGTCTAACGGATCTTGATTTGT
GTGGACTTCCTTAGAAGTAACCGAAGCACAGGCGCTACCATGAGATATATGTGGGTAATT
AGATAATTGTTGGGATTCCATTGTTGATAAAGGCTATAATATTAGGTATACAGAATATAC
TAGAAGTTCTCCTCGAGGATTTAGGAATCCATAAAAGGGAATCTGCAATTCTACACAATT
CTATAAATATTATTATCATCGTTTTATATGTTAATATTCATTGATCCTATTACATTATCA
ATCCTTGCGTTTCAGCTTCCACTAATTTAGATGACTATTTCTCATCATTTGCGTCATCTT
CTAACACCGTATATGATAATATACTAGTAACGTAAATACTAGTTAGTAGATGATAGTTGA
TTTTTATTCCAACAATGGCCTCTTTAACACTAATATCCCGACAATTTTCCCAAAATTCAA
AGAATTCTCAGAAAGAGCTATTTTTTTTTTTAATAAAATTATTAGTACTAATTCCAGTAT
AAATAACAATGTTATTTACGTCTCTTTCGAAAATGCTCGTGTAGCTCAGTGGTTAGAGCT
TCGTGCTTATAGCAACATTCGGTTTCCGAAGTTTCTGTGCCAAAGACCTTTCAAACAGGC
CTTTAAAAGCAACGCGACCGTCGTGGGTTCAAACCCCACCTCGAGCACTTTCTCTTTTTT
TTTCACACGCGTTTGCAACATGCCCGTATTACATGAGCTTATTTGACTTTAGATGGTTTT
CAGTTCTTTTTTTTTTTTTTTTTTTTTTCAGTAGATTAATGCGAAGAGTTAAATCACCAA
TTCAAAGATGGCAGATGGACCACCTTGTGGGATAAGTATAAAAATAACTAAAAGTGGTCT
TGTGTTAAAAATAGAATAGAAACCACTCATAAGGCAAAAG
Chr coordinates
Chr IV from 884727-886865
