Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name UPC2
Systematic Name YDR213W
Alias MOX4
Strain S288c
Description Sterol regulatory element binding protein; induces sterol biosynthetic genes, upon sterol depletion; acts as a sterol sensor, binding ergosterol in sterol rich conditions; relocates from intracellular membranes to perinuclear foci upon sterol depletion; redundant activator of filamentation with ECM22, up-regulating the expression of filamentous growth genes; contains a Zn[2]-Cys[6] binuclear cluster; UPC2 has a paralog, ECM22, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>UPC2 YDR213W
GTAAAATTGTGGACGAGATTCACGCTGGTGTTCTTGAGCCAACCATAAGCAAAGTCAAAT
CCTTGAAATCAGCATTGGAGGCTTGTGTAGCAATTCTAAGAATTGATACAATGATTACAG
TGGATCCAGAACCACCCAAAGAAGATCCGCACGATCATTGATTCTTTGCGTAATCCGAAC
GAGATTCTGTATCTGCATGTAAACTAATAAACCTATATAAAATTTAATTATATTTTTTTC
AGCTAGTTCTATTTTTGAATTTGATCGCTAACTCTGGGCAGTTGATAAGCGCTTCCCAGC
TTTTCACGTGCGAGGTGGACTAATACGTAATAACGCGTACCTATTAGGACTTCGTTGAGT
TGTTTTTCTTGTCCAAATGCAGAAGCGGGTCCCTACAAACTATTGTGTTTGTTCGTAAAC
GAGCAGGAACCCTGTTAAAGGAAAAAAGCTTAACGCTAGCGTTACATTTTAGTAAGGCGG
CAATAAAAAAGAATGCGGAGTGTATTCCATGAATTCAATTGCGCTTACTGCTAAGCCTGT
TTCTAAACATGATCCCCAGGGTGAATATCTCCCATAGTGGCTGTGTTATTCTGTCTAAAT
GTGGCAGCTAAATAAGGTTTTTTCCAAGCTATTTTTTTCTCTAAACGAGCGCACCTTAGC
GGGATCGCGTCAAATTTTCGCCCAACGAATATTATTCTATTGTCTTCAGTGAATGTGCTT
GTCGAAATCTATATATGCGCCGCCCTGGCAGGATCAGCAAATACAAGTTACTTGGAAAGT
CGCGGCATAGAAAGTAGACACTTCTTTTGTCAAAGATTGATATTGCTTTCAGGGTGCGAT
AGTGCTGACTGTTCCTCTAAACAGCGATTTTTTACATACATTAACTTTTTGAAGTTGTAG
GAACTATCTTTTCTCATTTATCCAACACTAAAACAAAATTGAGCTTTCCAGAAATAGTGA
ATCAAAAAAAGTTAAGTACAAATATTTACAGTTCAGCAGT
Chr coordinates Chr IV from 889751-892492
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