Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
UPC2
Systematic Name
YDR213W
Alias
MOX4
Strain
S288c
Description
Sterol regulatory element binding protein; induces sterol biosynthetic genes, upon sterol depletion; acts as a sterol sensor, binding ergosterol in sterol rich conditions; relocates from intracellular membranes to perinuclear foci upon sterol depletion; redundant activator of filamentation with ECM22, up-regulating the expression of filamentous growth genes; contains a Zn[2]-Cys[6] binuclear cluster; UPC2 has a paralog, ECM22, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>UPC2 YDR213W
ATGAGCGAAGTCGGTATACAGAATCACAAGAAAGCGGTGACAAAACCCAGAAGAAGAGAA
AAAGTCATCGAGCTAATTGAAGTGGACGGCAAAAAGGTGAGTACGACTTCAACCGGTAAA
CGTAAATTCCATAACAAATCAAAGAATGGGTGCGATAACTGTAAAAGAAGAAGAGTTAAG
TGTGATGAAGGGAAGCCAGCCTGTAGGAAGTGCACAAATATGAAGTTGGAATGTCAGTAT
ACACCAATCCATTTAAGGAAAGGTAGAGGAGCAACAGTAGTGAAGTATGTCACGAGAAAG
GCAGACGGTAGCGTGGAGTCTGATTCATCGGTAGATTTACCTCCTACGATCAAGAAGGAG
CAGACACCGTTCAATGATATCCAATCAGCGGTAAAAGCTTCAGGCTCATCCAATGATTCC
TTTCCATCAAGCGCCTCTACAACTAAGAGTGAGAGCGAGGAAAAGTCATCGGCCCCTATA
GAGGACAAAAACAATATGACTCCTCTAAGTATGGGCCTCCAGGGTACCATCAATAAGAAA
GATATGATGAATAACTTTTTCTCTCAAAATGGCACTATTGGTTTTGGTTCTCCTGAAAGA
TTGAATTCAGGTATCGATGGCTTACTATTACCGCCATTGCCTTCTGGAAATATGGGTGCG
TTCCAACTTCAGCAACAGCAGCAAGTGCAGCAGCAATCTCAACCACAGACCCAAGCGCAG
CAAGCAAGTGGAACTCCAAACGAGAGATATGGTTCATTCGATCTTGCGGGTAGTCCTGCA
TTGCAATCCACGGGAATGAGCTTATCAAATAGTCTAAGCGGGATGTTACTATGTAACAGG
ATTCCTTCCGGCCAAAACTACACTCAACAACAATTACAATATCAATTACACCAGCAGCTG
CAATTGCAACAGCATCAGCAAGTTCAGCTGCAGCAGTATCAACAATTACGTCAGGAACAA
CACCAACAAGTTCAGCAACAACAACAGGAACAACTCCAGCAATACCAACAACATTTTTTG
CAACAGCAGCAACAAGTACTGCTTCAGCAAGAGCAACAACCTAACGATGAGGAAGGTGGC
GTTCAGGAAGAAAACAGCAAAAAGGTAAAGGAAGGGCCTTTACAATCACAAACAAGCGAA
ACTACTTTAAACAGCGATGCTGCTACATTACAAGCTGATGCATTATCTCAGTTAAGTAAG
ATGGGGCTAAGCCTAAAGTCGTTAAGTACCTTTCCAACAGCTGGTATTGGTGGTGTTTCC
TATGACTTTCAGGAACTGTTAGGTATTAAGTTTCCAATAAATAACGGCAATTCAAGAGCT
ACTAAGGCCAGCAACGCAGAGGAAGCTTTGGCCAATATGCAAGAGCATCATGAACGTGCA
GCTGCTTCTGTAAAGGAGAATGATGGTCAGCTCTCTGATACGAAGAGTCCAGCGCCATCG
AATAACGCCCAAGGGGGAAGTGCTAGTATTATGGAACCTCAGGCGGCTGATGCGGTTTCG
ACAATGGCGCCTATATCAATGATTGAAAGAAACATGAACAGAAACAGCAACATTTCTCCA
TCAACGCCCTCTGCAGTGTTGAATGATAGGCAAGAGATGCAAGATTCTATAAGTTCTCTA
GGAAATCTGACAAAAGCAGCCTTGGAGAACAACGAACCAACGATAAGTTTACAAACATCA
CAGACAGAGAATGAAGACGATGCATCGCGGCAAGACATGACCTCAAAAATTAATAACGAA
GCTGACCGAAGTTCTGTTTCTGCTGGTACCAGTAACATCGCTAAGCTTTTAGATCTTTCT
ACCAAAGGCAATCTGAACCTGATAGACATGAAACTGTTTCATCATTATTGCACAAAGGTC
TGGCCTACGATTACAGCGGCCAAAGTTTCTGGGCCTGAAATATGGAGGGACTACATACCG
GAGTTAGCATTTGACTATCCATTTTTAATGCACGCTTTGTTGGCATTCAGTGCCACCCAT
CTTTCGAGGACTGAAACTGGACTGGAGCAATACGTTTCATCTCACCGCCTAGACGCTCTG
AGATTATTAAGAGAAGCTGTTTTAGAAATATCTGAGAATAACACCGATGCGCTAGTTGCC
AGCGCCCTGATACTAATCATGGACTCGTTAGCAAATGCTAGTGGTAACGGCACTGTAGGA
AACCAAAGTTTGAATAGCATGTCACCAAGCGCTTGGATCTTTCATGTCAAAGGTGCTGCA
ACAATTTTAACCGCTGTGTGGCCTTTGAGTGAAAGATCTAAATTTCATAACATTATATCT
GTTGATCTTAGCGATTTAGGCGATGTCATTAACCCTGATGTTGGAACAATTACTGAATTG
GTATGTTTTGATGAAAGTATTGCCGATTTGTATCCTGTCGGCTTAGATTCGCCATATTTG
ATAACACTAGCTTATTTAGATAAATTGCACCGTGAAAAAAACCAGGGTGATTTTATTCTG
CGGGTATTTACATTTCCAGCATTGCTAGACAAGACATTCCTGGCATTACTGATGACAGGT
GATTTAGGTGCAATGAGAATTATGAGATCATATTATAAACTACTTCGAGGATTTGCCACA
GAGGTCAAGGATAAAGTCTGGTTTCTCGAAGGAGTCACGCAGGTGCTGCCTCAAGATGTT
GACGAATACAGTGGAGGTGGTGGTATGCATATGATGCTAGATTTCCTCGGTGGCGGATTA
CCATCGATGACAACAACAAATTTCTCTGATTTTTCGTTATGA
Promoter Sequence
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>UPC2 YDR213W
GTAAAATTGTGGACGAGATTCACGCTGGTGTTCTTGAGCCAACCATAAGCAAAGTCAAAT
CCTTGAAATCAGCATTGGAGGCTTGTGTAGCAATTCTAAGAATTGATACAATGATTACAG
TGGATCCAGAACCACCCAAAGAAGATCCGCACGATCATTGATTCTTTGCGTAATCCGAAC
GAGATTCTGTATCTGCATGTAAACTAATAAACCTATATAAAATTTAATTATATTTTTTTC
AGCTAGTTCTATTTTTGAATTTGATCGCTAACTCTGGGCAGTTGATAAGCGCTTCCCAGC
TTTTCACGTGCGAGGTGGACTAATACGTAATAACGCGTACCTATTAGGACTTCGTTGAGT
TGTTTTTCTTGTCCAAATGCAGAAGCGGGTCCCTACAAACTATTGTGTTTGTTCGTAAAC
GAGCAGGAACCCTGTTAAAGGAAAAAAGCTTAACGCTAGCGTTACATTTTAGTAAGGCGG
CAATAAAAAAGAATGCGGAGTGTATTCCATGAATTCAATTGCGCTTACTGCTAAGCCTGT
TTCTAAACATGATCCCCAGGGTGAATATCTCCCATAGTGGCTGTGTTATTCTGTCTAAAT
GTGGCAGCTAAATAAGGTTTTTTCCAAGCTATTTTTTTCTCTAAACGAGCGCACCTTAGC
GGGATCGCGTCAAATTTTCGCCCAACGAATATTATTCTATTGTCTTCAGTGAATGTGCTT
GTCGAAATCTATATATGCGCCGCCCTGGCAGGATCAGCAAATACAAGTTACTTGGAAAGT
CGCGGCATAGAAAGTAGACACTTCTTTTGTCAAAGATTGATATTGCTTTCAGGGTGCGAT
AGTGCTGACTGTTCCTCTAAACAGCGATTTTTTACATACATTAACTTTTTGAAGTTGTAG
GAACTATCTTTTCTCATTTATCCAACACTAAAACAAAATTGAGCTTTCCAGAAATAGTGA
ATCAAAAAAAGTTAAGTACAAATATTTACAGTTCAGCAGT
Chr coordinates
Chr IV from 889751-892492