Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SIR4 Systematic Name
YDR227W Alias
ASD1, STE9, UTH2 Strain
S288c Description
SIR protein involved in assembly of silent chromatin domains; silent information regulator (SIR) along with SIR2 and SIR3; involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; some SIR4 alleles prolong lifespan; required for Ku-mediated telomerase recruitment, telomere lengthening, and telomere hypercluster formation in quiescent yeast cells External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA View Seq
Sequence hidden Promoter Sequence
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>SIR4 YDR227W
GTTTCCATGCCGCTCACTTGGCCACTGGTGACATGTTGAGATCTCAAATCGCAAAGGGCA
CTCAATTAGGTTTGGAAGCAAAGAAAATTATGGACCAAGGTGGTTTAGTCTCTGATGACA
TTATGGTTAACATGATCAAGGATGAATTGACCAACAATCCAGCTTGTAAGAATGGGTTCA
TCTTGGACGGTTTCCCAAGAACCATTCCTCAGGCTGAAAAATTGGACCAAATGTTGAAAG
AACAAGGAACTCCTTTGGAAAAAGCCATCGAATTGAAGGTTGATGATGAATTGTTGGTTG
CCAGAATTACCGGTAGATTAATTCACCCAGCCTCTGGCAGATCCTACCACAAGATCTTTA
ACCCACCAAAGGAAGACATGAAGGATGACGTCACCGGTGAAGCTTTAGTTCAAAGATCTG
ATGACAATGCAGACGCCTTGAAGAAGAGATTAGCTGCTTACCATGCTCAAACCGAACCAA
TTGTTGACTTTTACAAAAAGACCGGTATCTGGGCTGGTGTTGATGCTTCCCAACCTCCTG
CTACTGTTTGGGCTGACATCTTGAACAAGCTAGGTAAGGATTAATGACCTTGCGCAATGT
CTTCTAAATATCTTTTCTTTTTTTTAAATTAATGAAAATATAATAAATTTTTGTATGTGA
GTACATATATCCGCAGTATACTATAAATGAAATAATAACATAAGTGTTTGTAACTGGCTA
TAACGTCCTTAAACATGTGCACTGCCATTAAGTACTTAGTCAATATTTTTATCGTTGAGA
ACGAACGCAAATCATATTACTAAATAGATGAACAAAAGCGCATCACATAAACAAAAACGG
TATAACAGTAATAGTGAAGCTTTTTATAAACCTATAACGAAATAAGCGCTTTTCAGGTTT
TATAATTCAGTCAGAGTTCTAACTGGACATCGTTTTGCAGGGGATAAAAAAAAAAAGGAA
GCTTCAACCCACAATACCAAAAAAGCGAAGAAAACAGCCA
Chr coordinates
Chr IV from 917571-921647
