Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SIR4 Systematic Name
YDR227W Alias
ASD1, STE9, UTH2 Strain
S288c Description
SIR protein involved in assembly of silent chromatin domains; silent information regulator (SIR) along with SIR2 and SIR3; involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; some SIR4 alleles prolong lifespan; required for Ku-mediated telomerase recruitment, telomere lengthening, and telomere hypercluster formation in quiescent yeast cells External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>SIR4 YDR227W
ATGCCAAATGACAATAAGACACCCAATAGGTCCAGCACTCCCAAGTTTACTAAAAAACCA
GTAACCCCGAATGATAAAATTCCTGAAAGAGAAGAAAAATCCAATGAAGTGAAGACACCT
AAAATTCCATTATTCACGTTTGCCAAAAGCAAAAACTATTCAAGGCCGTCAACCGCAATT
CATACCTCACCTCATCAACCAAGTGATGTAAAACCGACTTCCCATAAACAGTTGCAACAG
CCAAAATCCTCACCACTGAAAAAAAATAACTATAATTCTTTTCCTCACTCAAATCTGGAA
AAAATAAGCAACAGCAAACTACTCTCCCTTCTTCGGTCCAAAACGTCAGCAGGAAGAATT
GAATCAAACAATCCTTCACATGATGCTAGCAGGTCTCTAGCAAGTTTTGAACAAACAGCA
TTTTCCCGGCATGCGCAGCAACAAACTTCTACCTTCAATTCAAAGCCTGTACGTACCATA
GTACCGATATCAACATCACAAACCAATAACTCATTTTTATCAGGAGTAAAAAGCTTACTA
AGTGAAGAGAAAATAAGGGATTACTCTAAAGAGATTCTAGGCATAAACTTGGCAAACGAA
CAGCCTGTTTTAGAGAAGCCACTTAAAAAAGGATCAGCAGACATCGGCGCCTCTGTGATT
TCTTTGACCAAGGACAAATCTATCAGGAAAGATACCGTAGAAGAAAAAAAAGAAGAAAAG
TTGAATATAGGTAAAAACTTTGCCCATTCTGATTCACTATCAGTTCCGAAGGTTAGTGCC
GGTGACAGTGGTATATCACCGGAGGAGAGCAAGGCAAGAAGTCCTGGAATTGCAAAACCG
AATGCCATACAAACAGAAGTGTATGGAATAAATGAGGAATCTACTAACGAGCGTTTAGAA
ATAAATCAAGAAAAACCAGTAAAATTAGATGAGAATAGTGCAAATAGTACGGTCGCATCG
GCCTTAGATACCAATGGGACGTCAGCCACGACAGAAACTCTAACATCAAAGAAGATCGTT
CCATCTCCAAAAAAAGTCGCCATTGATCAAGATAAAATAACACTGCACGATGAGAAAACA
CTTGCACCTTCGAAGCATCAGCCTATAACATCTGAACAAAAAATGAAGGAAGACGCCGAC
CTCAAGAGGATGGAAATCTTAAAGTCACCTCATTTGTCGAAAAGTCCAGCTGACAGACCT
CAAGGGCGTAGAAACAGCCGAAATTTTTCCACTAGAGATGAAGAAACTACAAAACTTGCT
TTTCTTGTTGAATATGAAGGCCAAGAAAACAACTATAACTCTACTTCTCGAAGCACAGAA
AAGAAAAATGATATGAACACTTCTGCAAAGAATAAAAATGGTGAAAACAAGAAAATTGGT
AAGAGGCCGCCTGAAATCATGAGCACTGAAGCTCACGTAAACAAAGTAACCGAAGAAACC
ACAAAGCAGATACAGAGTGTACGAATAGATGGTCGAAAAGTGCTTCAAAAAGTACAAGGA
GAATCCCACATTGATTCGAGAAACAATACCCTGAATGTTACACCATCAAAGAGGCCCCAG
CTAGGAGAAATACCGAATCCTATGAAAAAGCATAAGCCTAATGAAGGGCGAACTCCAAAT
ATCTCAAACGGTACAATAAACATCCAAAAGAAATTAGAGCCTAAGGAAATTGTGCGAGAT
ATTTTGCATACGAAAGAATCATCAAATGAGGCTAAGAAAACTATTCAAAACCCTTTAAAT
AAATCACAAAACACTGCTCTTCCTTCCACACATAAAGTTACACAAAAAAAAGATATAAAA
ATTGGAACTAATGACCTTTTTCAGGTTGAATCTGCTCCAAAAATATCCTCAGAGATTGAC
CGGGAGAATGTTAAATCAAAGGATGAACCGGTTTCCAAGGCTGTTGAAAGCAAATCTTTA
TTAAATTTGTTTTCAAACGTACTCAAGGCTCCTTTCATTAAAAGTGAAAGCAAACCTTTT
TCTAGTGATGCTCTGTCAAAAGAAAAAGCCAATTTTTTGGAAACTATCGCTTCCACTGAA
AAGCCAGAAAATAAGACTGATAAGGTGTCTCTATCTCAGCCAGTTAGTGCAAGTAAGCAT
GAGTATAGCGATAATTTTCCAGTTTCTCTATCTCAACCTTCAAAGAAATCTTTCGCAAAT
CATACAGAGGATGAGCAAATTGAAAAAAAGAAGATCTGCCGTGGGAGAATGAATACGATA
ATAACTCACCCGGGAAAAATGGAGCTGGTATACGTGTCCGACTCAGACGATTCTTCTTCA
GATAATGATAGCCTAACTGACTTGGAAAGTTTAAGCTCTGGTGAATCAAATGAAATCAAA
GTAACTAATGATTTAGATACAAGTGCTGAAAAGGACCAAATTCAGGCAGGCAAATGGTTT
GATCCTGTATTGGATTGGCGAAAATCTGATCGTGAATTGACGAAAAACATTCTTTGGAGG
ATAGCTGATAAAACGACATACGATAAAGAAACAATAACTGACCTTATTGAACAAGGGATC
CCAAAACATAGTTATTTAAGTGGCAATCCATTAACTAGTGTGACTAACGACATTTGCTCT
GTTGAAAACTATGAAACATCAAGTGCTTTCTTTTACCAACAAGTGCACAAGAAGGACAGA
TTACAATATTTGCCATTATATGCAGTTTCTACATTTGAAAACACAAATAACACTGAAAAA
AATGATGTGACCAATAAAAATATCAATATAGGGAAACATAGCCAAGAACAAAATTCTTCT
TCCGCTAAACCATCCCAAATTCCAACCGTGTCTTCTCCATTAGGATTCGAAGAAACAAAG
CTAAGTACCACGCCTACTAAAAGCAATAGAAGAGTGTCGCATAGTGATACTAATTCTAGC
AAACCCAAAAACACGAAGGAGAACCTTTCAAAAAGCTCTTGGAGGCAAGAATGGCTTGCA
AATTTGAAACTTATTTCCGTTTCGTTGGTTGATGAGTTCCCTTCGGAGCTTTCCGACAGT
GATAGACAAATAATTAACGAAAAAATGCAGTTACTTAAAGATATATTTGCTAACAACCTT
AAATCAGCAATTTCCAATAATTTTAGAGAGAGTGACATCATTATACTGAAAGGTGAAATA
GAAGATTACCCAATGAGTTCTGAAATTAAGATTTACTACAACGAATTACAGAACAAGCCT
GATGCAAAAAAAGCCAGATTTTGGTCATTTATGAAGACTCAGAGATTTGTTTCCAACATG
GGATTTGATATTCAGAAGTCCTGTGAACCTGTTTCTATATCCACGTCGGTCAAACCACAT
GTGGTCGAGCCCGAGCATATGGCAGATGCCAAAATTATGCCTAAGGATATACTGCAAATT
ACAAAAAAACCGTTAATGGTTAAAAATGTGAAGCCTTCTTCTCCGCCAGATGTGAAGTCT
TTGGTGCAGCTGAGCACAATGGAAACGAAAACCCTACCAGAAAAGAAGCAATTCGACAGT
ATTTTTAATTCTAACAAAGCAAAAATAATCCCTGGAAATGGGAAGCACGCATCAGAAAAC
ATCTCACTCTCTTTCTCAAGACCTGCGTCCTACGGCTATTTTTCTGTTGGAAAAAGGGTT
CCAATCGTTGAAGATCGTCGAGTGAAACAACTCGACGATATAACAGACAGTAATACAACA
GAAATTTTAACTAGTGTTGACGTTTTAGGAACACATTCACAAACTGGTACTCAACAATCA
AATATGTACACATCAACCCAAAAAACAGAACTTGAAATTGATAATAAGGATAGTGTCACC
GAATGTTCGAAGGACATGAAAGAAGATGGTCTTTCCTTTGTGGATATCGTTTTGTCGAAA
GCAGCATCGGCGCTGGATGAAAAGGAAAAACAATTGGCTGTTGCAAATGAAATTATTCGG
TCTTTGTCAGATGAAGTTATGAGGAATGAAATTAGAATAACTTCACTTCAAGGTGATTTA
ACTTTTACAAAGAAATGTCTTGAAAATGCGAGAAGTCAAATATCTGAAAAAGATGCTAAA
ATTAACAAATTGATGGAAAAAGATTTTCAAGTGAATAAGGAGATAAAACCGTATTGA Promoter Sequence
Download FASTA
>SIR4 YDR227W
GTTTCCATGCCGCTCACTTGGCCACTGGTGACATGTTGAGATCTCAAATCGCAAAGGGCA
CTCAATTAGGTTTGGAAGCAAAGAAAATTATGGACCAAGGTGGTTTAGTCTCTGATGACA
TTATGGTTAACATGATCAAGGATGAATTGACCAACAATCCAGCTTGTAAGAATGGGTTCA
TCTTGGACGGTTTCCCAAGAACCATTCCTCAGGCTGAAAAATTGGACCAAATGTTGAAAG
AACAAGGAACTCCTTTGGAAAAAGCCATCGAATTGAAGGTTGATGATGAATTGTTGGTTG
CCAGAATTACCGGTAGATTAATTCACCCAGCCTCTGGCAGATCCTACCACAAGATCTTTA
ACCCACCAAAGGAAGACATGAAGGATGACGTCACCGGTGAAGCTTTAGTTCAAAGATCTG
ATGACAATGCAGACGCCTTGAAGAAGAGATTAGCTGCTTACCATGCTCAAACCGAACCAA
TTGTTGACTTTTACAAAAAGACCGGTATCTGGGCTGGTGTTGATGCTTCCCAACCTCCTG
CTACTGTTTGGGCTGACATCTTGAACAAGCTAGGTAAGGATTAATGACCTTGCGCAATGT
CTTCTAAATATCTTTTCTTTTTTTTAAATTAATGAAAATATAATAAATTTTTGTATGTGA
GTACATATATCCGCAGTATACTATAAATGAAATAATAACATAAGTGTTTGTAACTGGCTA
TAACGTCCTTAAACATGTGCACTGCCATTAAGTACTTAGTCAATATTTTTATCGTTGAGA
ACGAACGCAAATCATATTACTAAATAGATGAACAAAAGCGCATCACATAAACAAAAACGG
TATAACAGTAATAGTGAAGCTTTTTATAAACCTATAACGAAATAAGCGCTTTTCAGGTTT
TATAATTCAGTCAGAGTTCTAACTGGACATCGTTTTGCAGGGGATAAAAAAAAAAAGGAA
GCTTCAACCCACAATACCAAAAAAGCGAAGAAAACAGCCA
Chr coordinates
Chr IV from 917571-921647
