Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
HEL2
Systematic Name
YDR266C
Alias
RQT1
Strain
S288c
Description
RING finger ubiquitin ligase (E3); subunit of ribosome-associated quality control trigger complex (RQT); involved in ubiquitination and degradation of excess histones; interacts with Ubc4p and Rad53p; required to trigger ribosome-associated quality control (RQC) and canonical no-go decay; ubiquitinates Rps20 and Rps3; binds to ribosomal RNA, mRNA and tRNA
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>HEL2 YDR266C
ATGGCATCCATCTGAAGCATTACTGGCTTCAAGTTCTTATGATGACACCGTCAGGATATG
GAAAGACTATGACGATGACTGGGAATGTGTTGCTGTCTTAAATGGCCATGAAGGAACTGT
TTGGTCTTCTGATTTTGACAAGACTGAGGGCGTGTTTAGACTGTGCAGTGGAAGCGACGA
TTCCACTGTACGGGTATGGAAATACATGGGTGACGACGAGGATGATCAACAAGAATGGGT
TTGTGAAGCTATTCTCCCGGATGTACACAAAAGACAGGTATACAATGTTGCATGGGGCTT
TAATGGCCTCATTGCTAGTGTAGGAGCGGATGGAGTACTAGCGGTCTATGAAGAAGTAGA
CGGAGAATGGAAAGTTTTTGCTAAACGTGCATTATGTCATGGAGTTTATGAAATCAACGT
TGTGAAGTGGTTGGAGTTAAATGGTAAAACTATACTTGCAACAGGCGGTGACGACGGGAT
CGTAAATTTCTGGTCTCTAGAAAAAGCAGCGTAGATGTAGAAGCAAGAGTACAATTCAGG
AACTCATATTAACACAGTGATCGATCTGAATTCTAAAAATAAACTTAATGACGATTTTTC
TACCTAGTTACATAAACCTTTGTATCACTATAACGCAATTCTGTCATGTGTGACGGAGTG
ACCTCGTTATACATATCCCTGCATTAAAAGCATGCGGTAAAAACTGAAATTTAAAAATGA
AAAAAAAAAAAATTAGATATTCGGAAGACTTGTAATTAAGCATTATCTCGAATAAAGAAA
GGTTACACTGAAAGTTTCATACTCGCGGTCACTCTTAATAATAGCTATATTTTCTGATTT
TCTCTTAAGATTTTGAAAAGGGCATCTGAACGACTGCCCACTCAGCCATATTCAACAAAT
CGTCGAGCGCATACCTAGCTGAAAAAGATCCATAAAGTGCATTTTGATACAGTCTCTTTC
GTCGAAAAAATAGTGGCTATACTTCTTTTCAAGAATTAGG
Chr coordinates
Chr IV from 1002023-1000104