Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name HEL2
Systematic Name YDR266C
Alias RQT1
Strain S288c
Description RING finger ubiquitin ligase (E3); subunit of ribosome-associated quality control trigger complex (RQT); involved in ubiquitination and degradation of excess histones; interacts with Ubc4p and Rad53p; required to trigger ribosome-associated quality control (RQC) and canonical no-go decay; ubiquitinates Rps20 and Rps3; binds to ribosomal RNA, mRNA and tRNA
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>HEL2 YDR266C
ATGAGCGAATCAGTGAAAGAAAACGTTACTCCGACACGTAACTTCCGTCGTACTCAAGGG
CCCCAAAATAATACAAAACCTCACAACGACAGGAAGAATTTCAGAAGAAAGCAAAAGAAA
AATAACCTTTCTGCTGAACCCAACCTCACCACTTCAAGCGCAGATGATACTGATGAAGAA
AATGAATTATGTGTAATTTGTGCGCGCAAGTTAACATACGTATCTCTAACACCATGCCAT
CATAAGACATGCCATATCTGTGGTTTCAGACAACGAGCTTTGTACAACAAGAAAAGCTGT
TTGATTTGCAGAACGGAGAATGAAGAAGTCATGTTTACCGATCGCATAGATGGTGATATT
TCAGATAAATATAACTTTTGCGAAAAAAATGAAAAATATGGAATAAATTTCACTAGCGAA
GAGGTTGCTACCGAAACACTAAATCTTTTAAAATTTTTTTGTCCCCTATCGAAGGATGAA
CAAGTTTGTGACTTTGGTAGTTTCAAGAAATATAATGAACACTTGAAATCTGAACATAAC
AGAATGATCTGTTTAATATGTGCAACCCATAAGCATGCATTCCCTTGTGAGCTTGAAATA
TTCACCCAAAATCAATTACGCAACCATCAAACTAAGGGTAATTCAGAAGGATTCAAAGGC
CACCCTATGTGTGCCTTCTGTTCCGGAAAACGATTTTATTCAGACGACGAATTGTACATT
CACATGAGAAATCAGCATGAAAAGTGCCATATTTGTGATAAGATGAACCCCGCTTCTCCT
CAATACTTTAAGGATTATAATCAGCTTTTTGACCACTTTAAACATTCGCATTACGTTTGC
ACCGTCCAAACTTGCTTAGATAACAAGTTTGTCGTATTTAAAGACGAGTTGGAGTTACAA
GCCCACATTTTGCAGGAGCATGGTAATATCCTGAAGGGAAAGCCAAAGTTTTTCCAGTCA
GAACTTTCTACTTTTATCTCGGCTCCATCTAGAGTGATCAGGGAAAGAGATGATTACGAC
CTTCCATCTATATCTTCCCTACCGGGTTCATCATCCGGCTCTAGAACTGATGTGAGATCT
GCTAGTTCTCCCGAGGAAAGTAGACTAAGATTGGCAGAAAGAGCAAAATACTATCTGGAA
AATTCCAAAGAAGACTTCAATAAGTTTTCTTCTTATAACGAAGATTATTCTAAAGGTCGC
TTAAGTGCTGAAAAATTATTGGAATCATATAAATTGTTATTCACAAAACCAAATGCGGAT
GTATATTTATTGATTCATAACTTAGCTGAAACCTTTCCCAAAAACTCCTCCAAATACAAT
AATCTGAACGCCATATATGAACAAAGAGAGCAAACCCTTGCACGACAAACTTCACTACCT
TCTTTATCTAGTGATTCTTCCCTTTCAATGTCAATAGGCAGGGGCCATTGGGGTGGAACA
AACGATGGGGGCAGCGCTGGTGCAGCATTAGGCGTTAGGAATATCAAAAATCTTCCAACC
CTGAAAAGTCCTTCAGCGTCGTATGATCCCTTTGCAACCACCGTAAAAAAAAACACTCTG
AGACCCGTGCAAAACATTAAAAGAACTACACCTCAATCAGTTAGTTATCGAACTTCCACT
AATACAGTCGCCTTCTCTCCAACCTATTTGGAAAGTAAAAAGGGTTCCTCTTCTACTTCT
CTAAATAATAGCAAAGATAAATTGAAAAGTCTCAACCTACCTCAACTACCTCCACCAAAG
CCAAAGGTGCAAATTCCAGGTCTGAACAGACCCCAAATTGCTGATCCTAAGCAGTGGGGT
AAAAAGTCAAGCACACAAGATACTAACGTGCACGATAATTTGAGGGAATTGAACACAACT
AGTGGAGGAAATAAAAAGAAAGGCAAACAAAAGCAGCTGTTATTCCACATTGGTGTATAG
Promoter Sequence
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>HEL2 YDR266C
ATGGCATCCATCTGAAGCATTACTGGCTTCAAGTTCTTATGATGACACCGTCAGGATATG
GAAAGACTATGACGATGACTGGGAATGTGTTGCTGTCTTAAATGGCCATGAAGGAACTGT
TTGGTCTTCTGATTTTGACAAGACTGAGGGCGTGTTTAGACTGTGCAGTGGAAGCGACGA
TTCCACTGTACGGGTATGGAAATACATGGGTGACGACGAGGATGATCAACAAGAATGGGT
TTGTGAAGCTATTCTCCCGGATGTACACAAAAGACAGGTATACAATGTTGCATGGGGCTT
TAATGGCCTCATTGCTAGTGTAGGAGCGGATGGAGTACTAGCGGTCTATGAAGAAGTAGA
CGGAGAATGGAAAGTTTTTGCTAAACGTGCATTATGTCATGGAGTTTATGAAATCAACGT
TGTGAAGTGGTTGGAGTTAAATGGTAAAACTATACTTGCAACAGGCGGTGACGACGGGAT
CGTAAATTTCTGGTCTCTAGAAAAAGCAGCGTAGATGTAGAAGCAAGAGTACAATTCAGG
AACTCATATTAACACAGTGATCGATCTGAATTCTAAAAATAAACTTAATGACGATTTTTC
TACCTAGTTACATAAACCTTTGTATCACTATAACGCAATTCTGTCATGTGTGACGGAGTG
ACCTCGTTATACATATCCCTGCATTAAAAGCATGCGGTAAAAACTGAAATTTAAAAATGA
AAAAAAAAAAAATTAGATATTCGGAAGACTTGTAATTAAGCATTATCTCGAATAAAGAAA
GGTTACACTGAAAGTTTCATACTCGCGGTCACTCTTAATAATAGCTATATTTTCTGATTT
TCTCTTAAGATTTTGAAAAGGGCATCTGAACGACTGCCCACTCAGCCATATTCAACAAAT
CGTCGAGCGCATACCTAGCTGAAAAAGATCCATAAAGTGCATTTTGATACAGTCTCTTTC
GTCGAAAAAATAGTGGCTATACTTCTTTTCAAGAATTAGG
Chr coordinates Chr IV from 1002023-1000104
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