Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MTH1
Systematic Name
YDR277C
Alias
BPC1, DGT1, HTR1
Strain
S288c
Description
Negative regulator of the glucose-sensing signal transduction pathway; required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation; MTH1 has a paralog, STD1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>MTH1 YDR277C
AGGAAGATTAAAATGAATTCTTCAACTTAGGGGTACTTTAAGAGAAAGAATTCAATACTT
GCGTTAGCTGACCACCCCATAGTTCGTTTAGATAAGGATATGGTGTGAAATTCATAGTTG
AAGACTCTTGAGGAGGTAGGGAACATCTCTCTTCGCCCACCAAACCCAGTTTTCTCTAAT
ACTCCATATCCAAAAAAGTGTAGCTCTATGTACATTGCCAAGGTTTTCTACTGATCAATA
TTTGATGGAAAAATATGACATAAGGTATGCGTATTAGTAAACTATTAGGGAGCCGCCGGT
ACTAATAACATCAAGGCCATCTCACGCCGAGACTTACTTGGACTTTTCTCTATTGTAAAG
CGGAAAAAAAGTTATCACCCCGCCCCCTCCTCCGCTCCTCCACTAAAACGATCAGCAAAT
GGCAGAATAACGCGGTACTAACCAGTTTTTCCGTTCCTTGAAACCCAGTCATACTATGAA
GTCCCTAAAATTATTCCGAAATTATTCCCTAGAACAAGCGGGAAAAAGGTCCGGGGAAAT
GGAGTCCGTGCGAGTTTTGTTAGGATGACTGCCCCACACATTTCCTCATCTTATAATTTT
GTGGAAAAATTCATCGTGAGAGAAAATACGAGTCCATTTCTCCAGTGAAACTACCGTAGA
CATGGAATATCTGCCATTCTACCCCTTATTCAAGTGCCTTTTTTTTTTTTTTTCATCCCA
CATTTTATTGCTGCCTCAATCTCCATTAAGAAAAAAAATTTATATAACCAAATGACATTT
TTCCTTTCTTCTCAAACTTTGTAATGCGCCTGTAACTGCTTCTTTTTTTATTAAAAAACA
GCATGGAGTTTTTTAATAACTTAAGGAAACATACAAAAAGATTTGTTCATTTCACTCCAA
GTATTTTTTAACGTATATTGAAAGTTCTCAATAGCGAAACCACAAGCAGCAATACAAAGA
GAATTTTATTCGAACGCATAGAGTACACACACTCAAAGGA
Chr coordinates
Chr IV from 1015702-1014401