Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name MTH1
Systematic Name YDR277C
Alias BPC1, DGT1, HTR1
Strain S288c
Description Negative regulator of the glucose-sensing signal transduction pathway; required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation; MTH1 has a paralog, STD1, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>MTH1 YDR277C
ATGTTTGTTTCACCACCACCAGCAACTTCGAAAAACCAAGTTTTACAACGACGTCCATTA
GAATCGACTAACAGTAATCATGGGTTTGCAAGCTCCCTACAGGCCATTCCGGAAAACACG
ATGAGTGGCAGTGATAATGCTTCTTTTCAAAGTTTGCCACTATCAATGAGTAGCTCTCAA
TCCACGACTTCTTCGAGAAGAGAGAACTTTGTGAATGCTCCTCCGGAGTACACTGATAGA
GCTAGAGATGAGATTAAAAAAAGATTATTGGCCTCCTCACCTAGCAGAAGGTCACATCAT
TCAAGCAGTATGCATTCAGCGAGCAGGAGATCAAGCGTGGCTGAAAGTGGGAGTTTACTT
TCGGATAATGCCTCGTCTTATCAATCAAGTATATTTTCTGCCCCCTCTACTGTGCACACG
CAACTAACTAATGACTCTTCGTTCTCCGAATTTCCTAACCACAAGTTAATCACGAGAGTG
AGCCTGGATGAAGCATTACCCAAAACGTTTTATGACATGTATTCGCCAGATATTCTATTA
GCAGACCCATCCAACATTCTCTGTAACGGGCGTCCCAAGTTTACCAAGAGAGAGTTATTG
GATTGGGATTTAAACGATATAAGATCGTTATTGATAGTCGAGAAGTTAAGGCCCGAATGG
GGTAATCAACTACCGGAAGTAATAACGGTGGGTGATAATATGCCCCAGTTTAGGTTACAA
TTATTACCACTATATTCTAGCGATGAGACCATAATCGCAACGTTAGTCCATTCGGATCTG
TACATGGAGGCTAACTTAGATTATGAATTCAAACTAACCAGCGCCAAATATACAGTAGCG
ACCGCTAGAAAAAGACATGAGCATATAACTGGTAGAAATGAAGCCGTCATGAATTTGTCG
AAACCGGAATGGAGAAATATCATCGAAAATTACCTCTTAAATATAGCAGTAGAGGCACAA
TGCAGGTTTGATTTCAAACAAAGATGCTCCGAATATAAGAAATGGAAGTTACAACAGTCC
AACTTAAAAAGACCGGACATGCCCCCACCAAGCATAATACCGCGGAAAAACAGCACAGAA
ACAAAATCGCTTCTGAAAAAGGCTTTATTGAAGAACATTCAGTTGAAAAACCCCAATAAT
AACCTTGATGAATTGATGATGAGATCAAGCGCCGCAACAAATCAACAGGGAAAAAACAAA
GTCAGCTTATCTAAAGAAGAAAAGGCTACGATATGGTCGCAATGTCAGGCACAAGTTTAC
CAAAGATTAGGATTGGATTGGCAGCCGGATTCAGTATCCTGA
Promoter Sequence
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>MTH1 YDR277C
AGGAAGATTAAAATGAATTCTTCAACTTAGGGGTACTTTAAGAGAAAGAATTCAATACTT
GCGTTAGCTGACCACCCCATAGTTCGTTTAGATAAGGATATGGTGTGAAATTCATAGTTG
AAGACTCTTGAGGAGGTAGGGAACATCTCTCTTCGCCCACCAAACCCAGTTTTCTCTAAT
ACTCCATATCCAAAAAAGTGTAGCTCTATGTACATTGCCAAGGTTTTCTACTGATCAATA
TTTGATGGAAAAATATGACATAAGGTATGCGTATTAGTAAACTATTAGGGAGCCGCCGGT
ACTAATAACATCAAGGCCATCTCACGCCGAGACTTACTTGGACTTTTCTCTATTGTAAAG
CGGAAAAAAAGTTATCACCCCGCCCCCTCCTCCGCTCCTCCACTAAAACGATCAGCAAAT
GGCAGAATAACGCGGTACTAACCAGTTTTTCCGTTCCTTGAAACCCAGTCATACTATGAA
GTCCCTAAAATTATTCCGAAATTATTCCCTAGAACAAGCGGGAAAAAGGTCCGGGGAAAT
GGAGTCCGTGCGAGTTTTGTTAGGATGACTGCCCCACACATTTCCTCATCTTATAATTTT
GTGGAAAAATTCATCGTGAGAGAAAATACGAGTCCATTTCTCCAGTGAAACTACCGTAGA
CATGGAATATCTGCCATTCTACCCCTTATTCAAGTGCCTTTTTTTTTTTTTTTCATCCCA
CATTTTATTGCTGCCTCAATCTCCATTAAGAAAAAAAATTTATATAACCAAATGACATTT
TTCCTTTCTTCTCAAACTTTGTAATGCGCCTGTAACTGCTTCTTTTTTTATTAAAAAACA
GCATGGAGTTTTTTAATAACTTAAGGAAACATACAAAAAGATTTGTTCATTTCACTCCAA
GTATTTTTTAACGTATATTGAAAGTTCTCAATAGCGAAACCACAAGCAGCAATACAAAGA
GAATTTTATTCGAACGCATAGAGTACACACACTCAAAGGA
Chr coordinates Chr IV from 1015702-1014401
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