Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
GIC2
Systematic Name
YDR309C
Strain
S288c
Description
Rho-family GTPase interacting protein and Cdc42p effector; required with Gic1p for cell polarity establishment and initiation of budding; involved in recruitment of septins to the presumptive bud site; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region; gic1 gic2 double mutants are defective for polarizing Cdc42p at elevated temperature, so may function both up- and downstream of Cdc42p; regulates mitotic exit
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>GIC2 YDR309C
ATGACTAGTGCAAGTATTACCAATACTGGAAACGAAACCATGAACCTTCCACAGATGCGG
TCGATTTGGCTGGATGAAGATGAAGAAGCTGAAAAACTCTACGGTCTGCAGGCCCAGCAA
TTCATGGGATCTGATGATGAAGAAAACCTAGGCATTACTTTCATCAACAGCGATAAACCT
GTGCTGAGTAACAAGAAAAACATTGAGTTGCCTCCACTTTCACCAAATTCACATCCGTCT
TGCCACCACAGGAGAAGTAATTCTAACTCTGCAAAGTCTAAAGAATCATCGTCATCATCG
TCCAGCGCCAACAAGACAAATCACAAAAAGGTTTTCCTTAAGCTTAATTTGTTGAAGAAA
AAGTTGCTTGGTGCCCAACCGGACATAAGAGGTAAAGGTATCTCCACACCATTTGATTTT
CAACATATTTCACATGCTGACACTAGAAATGGATTCCAAGATGAGCAATTGCAGGAACCT
TCATCGCTGTCCACAGAGATTAAGGACGACTATACCTCCTCCTCAAGCAAGCGGGATTCG
AAATCACTAAATAAAGCTTTTGTCACTGAAAGGATCCCTGCTAATCGTGAAAGCAAACTC
ATTTCAAGATCGCACGAAAATAAGACATCAAGACTATCAGTCGCGCGTTCGATCTCAGTA
ACGTCCTCCAATTACTCTAAAAACACACAAGGAAACAATCATTCCATTAATGGGAGAGTC
GTATCTACGTCAACTATGGCTACATCTATTTTTGAGTATTCCCCAAACGCATCTCCAAAA
CAATTTAAAAATAAGTCACACGCTCTGGGTCATAGATACACTAATTCCACGGATTCTAGT
GAGTCTTCGCTGGATTTTTTGAAGAACTACAACTTCCCCACACTACTTGAAGATAAGCCT
ATTTTAGACTTCTTGCCTCGTTCTCAGAGGTCAAGCGCTTATCGTAGCCTTTTAGAGACC
CCAAACTCAAATAAGGACTCAGCAAAAGCCTTCTTTCCTTCACGCCAAAGCCCTCTTCCC
AAGAGAAGAAACTCTATAGCTACGCCTTCTCCACAATCTAAATTTTCCTACTCTGACTCC
CCTGTAAACCATAGAAAATCTTTCGATGATGTTCTTTATTCTTTCAACCAGCTCGAGCCC
CTGCAAACTTAA
Promoter Sequence
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>GIC2 YDR309C
GACTTCCTTGATGACGGTTCAGAAAACAACCAGGTCAAATATTCCAGAATCATACCGCCA
GATATCCGTTAAGCTGGTCCGTACGTTGGGGCAGTTTCGAGAATAGATAAAAAAATGAAA
AATAAAAAAAAATAAAAAAAACACAAAATAATGGACCGTTACTATGCCCAACCAAGTAAC
CTCCCAACTTATTTGGAACATTACATATTTAGCGCTTAACATTACATACATATTTAGCGC
TTAACATTACATACACCTTTATCGACGAATTTGTAACTATTTCTTACTCTTGCGCTGAGG
AACGCCCCAGTCGTACAAAAGCACCTCTGCATACTAAGAAACTTAAACTATCGCCATTGT
CTCAAAATAGCAAAAAACGCAAAAAGCATACCGCTGGGCGCTTATCTATATTAACCTACA
CGAGAAAAGAAACATGATTGACTGCGTCAGATTCAAAAACCTGCAAAGTTTGTTTTTATA
ATTTTGGCGTTCAGCAAGCGCGCGGCTCCGCTCCATTAATATTCCAGAAAAAGAAATTCC
TTCTTTGGGTGTTGTGTATTGCTACTTTGGGCAGGCGCGACCGGGCCAAAAGAATGCGGC
ACCCGGCAAAGACGCGTTCTGGCCCCTGAAGACTTAAGCACTGGAATGGCTCCGAGGATT
GGTCACCCAGAAACAGGTGCAGACCAACCATTTCGAGATCTAGATGTTGCCTATTTCTCG
AGGAAACGCTGCCGTTATCGCCATGTTTGGTGGAACAATTGTGAAACGTGATCAATTCGT
GTTTGCAAGCTAGTGATCATTCGCATCCGAAAAAGAAACTGAAAATGTAAAACTCCAGTA
AAACGAGACCTGTTGATGGATTGTTTCGTGTCTGGTATATATTATTGCTACTGCTCAAGA
GAGCTTCTTTTTTTATGCTATCGAACTCGATCTTTCGCTCCGAAACACCTAACACTAACA
AAAGGAATACCTGACAGAATACGCTATCAAAAGAACGAAT
Chr coordinates
Chr IV from 1080199-1079048