Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SEM1 Systematic Name
YDR363W-A Alias
DSS1, HOD1 Strain
S288c Description
19S proteasome regulatory particle lid subcomplex component; role in Ub-dependent proteolysis and proteasome stability; involved in TREX-2 mediated mRNA export, and in the prevention of transcription-associated genome instability; ubiquitinated by Nedd4-like E3-ligase, Rsp5p; human ortholog DSS1, a BRCA1 binding protein implicated in cancer, complements the yeast null; drives trinucleotide repeat expansion; protein abundance increases in response to DNA replication stress External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SEM1 YDR363W-A
ATGAGTACGGACGTTGCTGCTGCACAAGCCCAAAGTAAAATAGATTTAACAAAAAAAAAA
AATGAGGAAATAAATAAGAAGTCTCTAGAGGAAGACGATGAATTTGAAGATTTCCCCATT
GACACATGGGCCAATGGTGAAACAATAAAAAGCAATGCTGTAACGCAAACAAACATATGG
GAAGAAAACTGGGATGATGTTGAAGTTGACGACGATTTCACCAATGAATTGAAGGCCGAA
TTGGATAGATACAAACGGGAAAATCAGTGA Promoter Sequence
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>SEM1 YDR363W-A
ATTAGGTGAAAACGAAGAAAAATAATAAATATGGTACTGTGCAGAATTGTTGATTTTCTT
TTTTGAACTCTAAACCATCAAGAATGGCTTTCACCCACTATTGTTACACATAGTACTATT
ACTTACACCAAGATGGGATCCGACAAATATCTCAACACTATATTGGTCTACATGCTTTAT
CGATTGCTCCTTATTTACGTATTTCTATAAATAGGGCGTACTTTACCAACAGTGATCATG
GATGCAAAAAATGTGAATACATTTATATGGAAAAAAGGTTTATATCAATATATTTTAAAG
TGATTGAAAATTACTGATGTGTTTGATATTGTTGGAATAAGAATCAACCATCATATACCC
GACTAACGTTCATATTATTAGTAAACTATCATATACAACCTAAGAAGTTGACATAAAGAT
TGACAAGCAGTTACCATTTTTAGTAGAAGTTGAAAAGCAAGAATTGATAACCAAATATTG
TTTTCCAACAATGCAATCCCAACCCTATCTCAATATTCATAGAATTCACTTATTTCTCAG
TTTAATACATGATGATGCATCTTGATATTGAGAAATTATATGTATTATCCCTTTTTAACC
TTTAAAAGGTCACAAATAAATAGCCTTGTTGGCGCAATCGGTAGCGCGTATGACTCTTAA
TCATAAGGTTAGGGGTTCGAGCCCCCTACAGGGCTAATAACACATTCAAAATGTTATAAA
TTTTTTTTCGGGTTTGTGTTTAAAACTAACCTTCTAAAGAAAACAATAAAAATTATATCA
ACATTTCCTCATGTCTTTGTAACCTACTAGTAGGGATTTTGAAGGGCTGAAAGCTTCTTA
GTTCTGTCGGATCCATTATATTATCATTATTTACGAAACTAGTGCTATGGGTGGCGAACG
TGGTGGGCGTTACCTTTTAAAGTCCTAATGGAAACCTACCTATGCATAAAGTGAATAGAG
TGGCAATAAAAGTCGAATAATAGTACAAATACGCAAAAAT
Chr coordinates
Chr IV from 1202128-1202397
