Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name YPR1
Systematic Name YDR368W
Strain S288c
Description NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>YPR1 YDR368W
ATGCCTGCTACGTTAAAGAATTCTTCTGCTACATTAAAACTAAATACTGGTGCCTCCATT
CCAGTGTTGGGTTTCGGCACTTGGCGTTCCGTTGACAATAACGGTTACCATTCTGTAATT
GCAGCTTTGAAAGCTGGATACAGACACATTGATGCTGCGGCTATCTATTTGAATGAAGAA
GAAGTTGGCAGGGCTATTAAAGATTCCGGAGTCCCTCGTGAGGAAATTTTTATTACTACT
AAGCTTTGGGGTACGGAACAACGTGATCCGGAAGCTGCTCTAAACAAGTCTTTGAAAAGA
CTAGGCTTGGATTATGTTGACCTATATCTGATGCATTGGCCAGTGCCTTTGAAAACCGAC
AGAGTTACTGATGGTAACGTTCTGTGCATTCCAACATTAGAAGATGGCACTGTTGACATC
GATACTAAGGAATGGAATTTTATCAAGACGTGGGAGTTGATGCAAGAGTTGCCAAAGACG
GGCAAAACTAAAGCCGTTGGTGTCTCTAATTTTTCTATTAACAACATTAAAGAATTATTA
GAATCTCCAAATAACAAGGTGGTACCAGCTACTAATCAAATTGAAATTCATCCATTGCTA
CCACAAGACGAATTGATTGCCTTTTGTAAGGAAAAGGGTATTGTTGTTGAAGCCTACTCA
CCATTTGGGAGTGCTAATGCTCCTTTACTAAAAGAGCAAGCAATTATTGATATGGCTAAA
AAGCACGGCGTTGAGCCAGCACAGCTTATTATCAGTTGGAGTATTCAAAGAGGCTACGTT
GTTCTGGCCAAATCGGTTAATCCTGAAAGAATTGTATCCAATTTTAAGATTTTCACTCTG
CCTGAGGATGATTTCAAGACTATTAGTAACCTATCCAAAGTGCATGGTACAAAGAGAGTC
GTTGATATGAAGTGGGGATCCTTCCCAATTTTCCAATGA
Promoter Sequence
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>YPR1 YDR368W
TTTTGTTAACTTGTAAGGATTCGAAGCAAAGCACAATTTTACTAACCTGTTCTCAAACAT
ATTTTTTTTTCATAGTCTTTTTTGGGGTTTATGCCGCTATACCTTGCAGTTGAGATTGTC
TTAGGTATTTCCATTCTAAACAAATGCAGTGGTGCTTATGGTATTTTAGCATTGTTCACG
GGTCATCCGTTGGATTTTATGCAATGGATAGCATATCTTTGGTCGGTATTTACATTAATC
GTATTCTCACAAGGGCTGTATTTGATTCATAAGCCAAACTTGCTGGTATTTTCGCAAATC
TGCGTACTTTATACAATCGATACCATTTCCACTTGTTTTTTTACTCTATGGTTTACCACG
CAATGGTTCACCTTGGAAGACACTGCTAATATTGATGGAAATAATGCACTACAAAGTAAC
CCAATATCGACAGGTAAGCTGACAGAACGTGGTATTGATATAAGTAAACAAAGTGCAACT
GAAAGCTACGAATATACCATGACTATTTTAATTACGTTGGTGTCATTGATATTCAGGTTC
TACTTTAACTTCATTTTGGCATCTTTTGTTCAAGAATTGTTACACCACCCCAAATATTTA
GTTGATAGGGATGACGTAGAACAAAACTTGAAAAACAAGCCTATTTGGAAAAGACTGTGG
GCTAAGAGCCAAAAAGGTTGTTATAAGCTATGTAAGAATTTGTTAGAGTAAATAGTAAAA
TAAAGCCCTAGCGTTATAGCGTTTTACACTGATGAAGAAATGTTTCTATTCTGACATCAT
AAAATCATTCTCACTGATGCTATTGTCACTTTTCATCACGTGTGTATTTAAGTAGCTCTT
ACGTAATTTTGAAAAAAAAGGAAAAAGGAAACTATATAGCACGCAATTCCCTATTTGGTT
GCAATTCAATTCCGTGAAACCCTTTTCTTTTCTAAAGTGATAATAAAGTAACTTTGCAAT
ATAATCAGGTCGCAAATATACCCACAGATAATAATCTACC
Chr coordinates Chr IV from 1213904-1214842
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