Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
BCS1
Systematic Name
YDR375C
Strain
S288c
Description
Protein translocase and chaperone required for Complex III assembly; member of the AAA ATPase family; forms a homo-oligomeric complex in the mitochondrial inner membrane that translocates the C-terminal domain of Rip1p from the matrix across the inner membrane and delivers it to an assembly intermediate of respiratory Complex III; also required for assembly of the Qcr10p subunit; mutation is functionally complemented by human homolog BCS1L, linked to neonatal diseases
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>BCS1 YDR375C
ATGTCGGATAAGCCGATTGACATACAATATGATAAACAGGCTACTCCAAATCTGAGTGGT
GTAATTACTCCGCCAACAAATGAAACTGGTAATGACTCAGTCCGGGAAAAACTTTCAAAA
CTAGTTGGCGATGCTATGTCAAACAATCCCTATTTTGCCGCCGGCGGTGGTCTTATGATC
CTTGGTACAGGTTTAGCTGTAGCTAGATCCGGTATAATAAAAGCCAGCAGGGTCCTATAC
CGACAAATGATTGTCGACTTAGAGATTCAGTCGAAGGACAAATCATACGCCTGGTTTCTA
ACATGGATGGCCAAACATCCTCAAAGGGTATCTAGACACTTATCCGTTAGGACAAACTAC
ATACAACATGACAATGGATCAGTTAGTACAAAATTTTCGCTGGTTCCGGGTCCGGGAAAT
CATTGGATTCGTTATAAGGGTGCTTTTATCCTGATTAAAAGAGAAAGGTCCGCAAAAATG
ATAGATATCGCAAACGGGTCACCATTTGAGACCGTAACCTTAACTACACTGTACCGTGAC
AAACATTTGTTCGATGACATTTTGAACGAGGCTAAAGACATAGCCCTGAAGACTACTGAG
GGCAAGACTGTTATTTACACTTCTTTCGGCCCTGAATGGAGAAAGTTTGGTCAACCAAAA
GCTAAAAGGATGCTGCCCTCCGTCATTTTGGACAGTGGCATCAAAGAGGGTATTCTCGAT
GACGTTTATGATTTTATGAAGAACGGCAAATGGTACTCTGACAGGGGTATCCCATATCGC
AGGGGATATTTACTCTATGGCCCTCCCGGATCTGGTAAGACTAGCTTTATCCAGGCTTTA
GCGGGCGAATTAGACTACAACATTTGTATTTTAAACCTCTCCGAAAATAATTTAACAGAT
GACAGATTAAACCACTTAATGAATAACATGCCAGAAAGGAGCATACTATTACTGGAAGAT
ATTGACGCGGCGTTCAACAAAAGAAGTCAAACTGGTGAACAAGGTTTTCATTCTAGCGTA
ACATTTAGCGGTTTACTGAATGCCCTGGATGGCGTCACATCTTCTGAAGAAACTATTACA
TTCATGACTACCAATCATCCTGAAAAGCTAGACGCGGCTATAATGAGACCAGGTCGTATT
GACTACAAAGTCTTCGTTGGTAACGCAACTCCATACCAGGTAGAAAAAATGTTTATGAAA
TTTTACCCAGGTGAGACTGATATATGCAAAAAGTTTGTAAATAGTGTTAAAGAATTGGAT
ATCACCGTAAGTACCGCCCAGTTGCAAGGACTTTTCGTTATGAATAAAGATGCACCACAC
GATGCGTTGAAAATGGTCTCCAGCTTACGGAACGCTAATCATATTTTCTAG
Promoter Sequence
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>BCS1 YDR375C
GTTCTCTTAATTCTTTGTTGGTGAATTTGGAATGAACGAAATCCCTTCGTGCAATTAGCT
TAACGTCCTTTACAGGTGCCCTTCTTAGCAAATTTAGTGCAAGAGATGAGATGTCCGTAT
TTTCCCATATTTCATCAATTTGATTAGAAATAAGTACACGCGTAATATCAAGAGCAACGT
TACCGTTTCCTATAATACCAACTTTCGAAACTTTGCTCCAGTCAAAATCGGTAAATCGCT
TATCCTTTGCGAAATCAGGATGACCATTGTACCAATTGACAAATTCTCTACTGCTAAACA
CCCCTTTTGTTCCGAGTTCGCCAGGGATATTCAGCTTTCTGTCCCCTGTACAACCATAAC
TTAAAATAACAGCATCTTGATTATCCAGCAATTCCTTCAACAATATTTCTTTTCCAATGG
TTATACCACCAACAAAGGAAAATTTATGCTTTTGGTTTGTAGGGGAAGAAAACTCTTCTG
CACATGTGGTAAACGTTTCTTCACAATTTTTGACTTCTGGATGATCAGGTGCCACACCAT
ATCTACTTAAACCAAAAGGAACAGGTAACTTTTCCCATATAGTAACATTTAATGGAATCG
GTGACTTCTTGAGTAAATGGTACGCTGTATAAAAGCCGGAAGGCCCCGATCCAACAATGG
ATACAGTCTTACGGTTTATTTGTGAAGAAATGTGCCTTATTTGAACAAAGCTCATTTTCA
CAAGTAATGAGCTAAAAAAGGAAGAAGAAAGAGTGAGAAACTTTCTAAATGAATGAATGA
GGCGTTGTGGCCAAGAACTATAGCAAGCAAAAAACTTTCTGTTACGTTCGAGCTATAGTT
TACTGCTCTTCGAATTATATCTCGATTGAGTTACCCTTAAAGAGTGCCGAAAAATCGATG
TAAATAGTATAAGTAAAGATTTCCACTCTTCTATATTTGCAACGCAGTAGACGTACCAAG
GGACGATTTGAAAAAAAATGAAGTGTGCCCTCAATCTACC
Chr coordinates
Chr IV from 1226536-1225166