Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
EFT2
Systematic Name
YDR385W
Strain
S288c
Description
Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin; EFT2 has a paralog, EFT1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>EFT2 YDR385W
ATGGTTGCTTTCACTGTTGACCAAATGCGTTCTTTAATGGACAAAGTTACCAATGTGCGT
AACATGTCCGTTATTGCTCACGTCGATCATGGTAAGTCCACTTTGACCGATTCCTTGGTC
CAAAGAGCCGGTATTATTTCCGCTGCTAAGGCTGGTGAAGCTCGTTTCACCGATACCAGA
AAGGATGAACAAGAAAGAGGTATCACTATCAAGTCTACCGCTATTTCTCTATACTCTGAA
ATGTCTGACGAAGATGTCAAGGAAATCAAGCAAAAGACCGACGGTAACTCCTTCTTGATC
AACTTGATCGACTCTCCAGGTCACGTTGACTTCTCCTCTGAAGTTACTGCCGCTTTACGT
GTCACTGACGGTGCTTTGGTTGTCGTCGACACCATTGAAGGTGTCTGTGTCCAAACCGAA
ACTGTTTTGAGACAAGCTTTGGGTGAGAGAATCAAGCCTGTTGTTGTTATCAACAAGGTC
GACAGAGCTTTGTTGGAATTGCAAGTTTCTAAGGAAGATTTATACCAAACCTTTGCCAGA
ACTGTTGAATCCGTTAACGTCATCGTTTCCACCTACGCCGATGAAGTTTTGGGTGATGTC
CAAGTTTACCCAGCCAGAGGTACCGTTGCCTTCGGTTCCGGTTTGCACGGTTGGGCTTTC
ACTATCCGTCAATTCGCCACCAGATATGCTAAGAAATTCGGTGTCGACAAGGCCAAGATG
ATGGACAGATTATGGGGTGACTCTTTCTTCAACCCAAAGACCAAGAAGTGGACCAACAAG
GACACTGATGCTGAAGGTAAGCCATTGGAAAGAGCTTTCAACATGTTCATCTTGGACCCA
ATCTTCAGATTATTCACTGCTATCATGAACTTCAAGAAAGATGAAATTCCAGTTTTGCTA
GAAAAGTTGGAAATTGTCTTGAAGGGTGACGAAAAGGACTTGGAAGGTAAGGCCTTGTTG
AAGGTTGTTATGAGAAAGTTCTTGCCAGCTGCCGATGCCTTATTGGAAATGATTGTCTTG
CACTTGCCATCTCCAGTCACTGCTCAAGCCTACAGAGCTGAACAATTATACGAAGGTCCA
GCTGACGATGCCAACTGTATTGCTATCAAGAACTGTGATCCAAAGGCTGATTTGATGTTG
TACGTCTCCAAGATGGTGCCAACCTCTGATAAGGGTAGATTCTACGCCTTCGGTAGAGTT
TTTGCCGGTACTGTTAAGTCCGGTCAAAAGGTCAGAATCCAAGGTCCAAACTACGTTCCA
GGTAAGAAGGACGATTTGTTCATCAAGGCCATTCAAAGAGTTGTTTTGATGATGGGTAGA
TTTGTCGAACCAATCGATGACTGTCCAGCCGGTAACATTATCGGTTTAGTCGGTATCGAT
CAATTCTTGTTGAAGACTGGTACTTTGACCACCAGTGAAACTGCTCACAACATGAAGGTC
ATGAAATTCTCTGTCTCTCCAGTTGTGCAAGTCGCTGTCGAAGTCAAGAACGCTAACGAC
TTACCAAAATTGGTCGAAGGTTTGAAGAGATTGTCCAAGTCTGATCCATGTGTCTTGACC
TATATGTCTGAATCCGGTGAACATATCGTTGCTGGTACCGGTGAATTGCATTTGGAAATT
TGTTTGCAAGATTTGGAACACGACCACGCTGGTGTTCCATTGAAGATCTCCCCACCAGTT
GTCGCTTACAGAGAAACTGTTGAAAGTGAATCTTCTCAAACTGCTTTGTCCAAGTCTCCA
AACAAGCATAACAGAATCTACTTGAAGGCTGAACCAATTGACGAAGAAGTCTCTTTGGCT
ATTGAAAACGGTATCATCAACCCAAGAGATGATTTCAAGGCCAGAGCTAGAATCATGGCT
GACGACTACGGTTGGGATGTCACCGATGCCAGAAAGATCTGGTGTTTCGGTCCAGACGGT
AACGGTCCAAACTTGGTTATTGACCAAACTAAGGCTGTCCAATACTTGCACGAAATCAAG
GATTCCGTTGTTGCTGCTTTCCAATGGGCTACCAAGGAAGGTCCAATTTTCGGTGAAGAA
ATGAGATCTGTCAGAGTTAACATTTTGGATGTTACTTTACATGCCGATGCTATCCACAGA
GGTGGTGGTCAAATCATCCCAACCATGAGAAGAGCTACTTACGCTGGTTTCTTGTTGGCT
GATCCAAAGATCCAAGAACCAGTTTTCTTGGTCGAAATTCAATGTCCAGAACAAGCCGTC
GGTGGTATCTACTCCGTCTTAAACAAGAAGAGAGGTCAAGTCGTTTCTGAAGAACAAAGA
CCAGGTACTCCATTGTTTACCGTCAAGGCCTACTTGCCAGTTAACGAATCTTTCGGTTTC
ACTGGTGAATTGAGACAAGCTACTGGTGGTCAAGCTTTCCCACAAATGGTTTTCGACCAT
TGGTCCACTTTAGGTTCTGACCCATTGGACCCAACCTCTAAGGCTGGTGAAATTGTTCTT
GCTGCTCGTAAGAGACACGGTATGAAGGAAGAAGTTCCAGGCTGGCAAGAATATTACGAC
AAATTGTAA
Promoter Sequence
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>EFT2 YDR385W
TCTCAAATCCATTGGTGTTTCCATTAGGCCCTGAGCGGTTCCCCAAGAAAAAAAAAAACA
GTAGAAAAAAATGATGCTTCTTCCTAACGCTATTGTAGTGCAGGTTCTGCCGTGTGCCAA
GTTGGAGCAGCGCCTGCTGAGACTCTTCCGTATGGTTCTTGCTCTTCTCAGGACCAGCGG
CGGCAGTTCCGGTTTTTTTCGGCGTCTTTTGTCTGGCACACAATGGGCGATGGAGAGGGA
AAACCGGAGGATATGCCAGCTGCGGTGAGATTATGGTTGGAGTTATGTTTGTAGCCGGCG
GTGCGGCAATAGGAGAGGGGAGGGGAAGGGGAGGGGAAAAGGTAATGGCTGACGAAGTAT
AGAGATGGCAATCACAAGCCAAATATTGGAGATTACATGCAAGAATGCTACTGTTATACA
AAAGGGTGAAAATTGAGACCCAAATTCCTTCCTTTTTTTTCTTTTTTTTTTACCAGAAGA
ATTACGTACAAAAGTACCTACTATTTCAAAGCAAGAAATGAGATGCCTATTGTGGTTATA
TACAGAATAGATGATAAATGGGTTTTCCGTGCAAAACGATATGGAGAATTCAAAATGGGT
GCGAAATACCTGGAACGTAAGCGTTCTGAGAAATACACAGACGCATTAACCTGACAAAAA
CACAACTAGTTTGGGAAAGGGATTTGGTCTTTCCTCTCGGGTCTCTCGTGTGGTTCCTTT
CTTTCTCAGATCTCCCTGCACACTGGGCTGTTGTCCTCCAGGTTATGGTTTGTTCTCTTC
AGGTATTACAATGCAGTAGGCTTTTGGAGTGAGCAAAACGAAGAGAGAAAAAAATTTTTT
CTTAAAAGTTTTTTTTCATTTTGTGAGCTTATTCTTCTTTTCTATATATTCTTGATATCT
TAGATTATACATATTATTCTCTTACATTTCACGATTGCCCTTTTGGTGTTTAGCATTCAG
ACTCAAAGACCACAAACACAAACTATAACATAATTGCAAG
Chr coordinates
Chr IV from 1243230-1245758