S.cerevisiae - Yeastract

Locus Information

Standard Name	MUS81
Systematic Name	YDR386W
Alias	SLX3
Strain	S288c
Description	Subunit of structure-specific Mms4p-Mus81p endonuclease; cleaves branched DNA; involved in DNA repair, replication fork stability, and joint molecule formation/resolution during meiotic recombination; promotes template switching during break-induced replication (BIR), causing non-reciprocal translocations (NRTs); helix-hairpin-helix protein; phosphorylation of non-catalytic subunit Mms4p by Cdc28p and Cdcp during mitotic cell cycle activates function of Mms4p-Mus81p
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>MUS81 YDR386W ATGGCTGACGACTACGGTTGGGATGTCACCGATGCCAGAAAGATCTGGTGTTTCGGTCCA GACGGTAACGGTCCAAACTTGGTTATTGACCAAACTAAGGCTGTCCAATACTTGCACGAA ATCAAGGATTCCGTTGTTGCTGCTTTCCAATGGGCTACCAAGGAAGGTCCAATTTTCGGT GAAGAAATGAGATCTGTCAGAGTTAACATTTTGGATGTTACTTTACATGCCGATGCTATC CACAGAGGTGGTGGTCAAATCATCCCAACCATGAGAAGAGCTACTTACGCTGGTTTCTTG TTGGCTGATCCAAAGATCCAAGAACCAGTTTTCTTGGTCGAAATTCAATGTCCAGAACAA GCCGTCGGTGGTATCTACTCCGTCTTAAACAAGAAGAGAGGTCAAGTCGTTTCTGAAGAA CAAAGACCAGGTACTCCATTGTTTACCGTCAAGGCCTACTTGCCAGTTAACGAATCTTTC GGTTTCACTGGTGAATTGAGACAAGCTACTGGTGGTCAAGCTTTCCCACAAATGGTTTTC GACCATTGGTCCACTTTAGGTTCTGACCCATTGGACCCAACCTCTAAGGCTGGTGAAATT GTTCTTGCTGCTCGTAAGAGACACGGTATGAAGGAAGAAGTTCCAGGCTGGCAAGAATAT TACGACAAATTGTAAGAATGGTTAAACAATTTTTAATTATTTAACTTTTTCAGTTTTTGT CGTAATGTATTGGGCACCTTTTATGTCCTTTTGACTTTTTTGTAGTTTATTCTCACGTAT ACTTACCATCTATAGTGTTATTTCATATTTAATCATATTTCCATATTAGATATCTGCCTT CCCCTGTATAATAGTTACTATGATTTATCTTGCTTTGCCTATTCGCGTCATCAACTTCTT TTCTTACCGATCGCGGTAATGCCCTTTAAGAGTGGCATCAACATTGGCGTAAACAAAGTT TCAAAGGATTGATACGAACACACATTCCTAGCATGAAAGC
Chr coordinates	Chr IV from 1246084-1247982