Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
HPT1
Systematic Name
YDR399W
Alias
BRA6, HGPRTase, HPRT
Strain
S288c
Description
Dimeric hypoxanthine-guanine phosphoribosyltransferase; catalyzes the transfer of the phosphoribosyl portion of 5-phosphoribosyl-alpha-1-pyrophosphate to a purine base (either guanine or hypoxanthine) to form pyrophosphate and a purine nucleotide (either guanosine monophosphate or inosine monophosphate); mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>HPT1 YDR399W
ATGTCGGCAAACGATAAGCAATACATCTCGTACAACAACGTACATCAACTATGTCAAGTA
TCCGCTGAGAGAATTAAGAATTTCAAGCCGGACTTAATCATTGCCATTGGTGGTGGTGGT
TTCATTCCTGCTAGGATCCTACGTACGTTCCTAAAGGAGCCCGGCGTGCCAACCATCAGA
ATTTTTGCTATTATTTTGTCTTTGTACGAAGATTTGAACAGTGTAGGCTCAGAAGTTGAG
GAAGTTGGTGTTAAGGTTAGCAGAACACAATGGATTGATTACGAGCAATGTAAATTAGAT
CTAGTCGGCAAGAACGTTCTTATCGTTGACGAAGTCGATGACACCCGTACCACACTTCAT
TACGCTTTGAGTGAATTGGAAAAGGATGCAGCTGAACAGGCAAAGGCTAAAGGTATCGAT
ACTGAAAAGTCTCCAGAGATGAAAACAAACTTCGGGATTTTTGTTCTACACGATAAGCAA
AAACCAAAGAAAGCAGATTTGCCTGCCGAAATGTTGAATGACAAGAACCGTTATTTTGCA
GCTAAAACTGTTCCAGACAAGTGGTATGCATATCCATGGGAATCTACTGACATTGTTTTC
CATACTAGAATGGCTATTGAACAGGGCAATGACATCTTTATTCCTGAGCAGGAACACAAG
CAATGA
Promoter Sequence
Download FASTA
>HPT1 YDR399W
GTTCCGACTTATTACCAAGGCTACTAGCACTGGATGCAAGGTTAGACTGTACTATAAATA
AATTCAAAACTTTGAACTATGAAGCAGGCGACATCCACTCATCCGAACCAGTTGTCGAAG
AGGACGAAGACGACGTTGAATATAACGAAGAACTCGATGATGCCGGCCTTATAGAGGACG
GTGAAGAATCTTATGGCAGTGAAGAAGAAGAAGAAGGTGATAGTGACAACGAAGAGGAAC
AGAAGCATACCTCATCTAAGCAAGATGGCCGTTTAGAAACGGAGCAGAGCGACGGCGAGG
AGGAAGCCGGATATAGTGACGTTGAGATGGAATAGAGGATATCATGCATAAAATGCTTTC
ACGCATCAGAATACAAAAATAATCTCTAGGCACATAAATACTTATATAGAGTTCACCACA
TAATGTAAGAAAAGAAAAAAGAAAAAAAAAGATCACGAAAGTATCCCACGCGAAGAAGAT
CTGTCAAAAGACCCCCACAATCGTTTATCCTTTTTGAACTGCATCTGGCATCGTTAACAG
TAAGGCCATCTGGAACATCAAGCAAGCACTCCACTTTTACGTCACAACCATAGTTGGTTA
ACTAAGAAAAGACAGTACATATTTCCCTTCCGAGTCACTTATTTTTTTTTTCTTCTGAAA
AAATTAATTAGATTAATTTCAATTAATATCATTTCCGCTTATCTGACTTCTTTCATTTTT
TTTCTCTATATTTCGCGTTTACTAGGAAAGAAAAGGAAAAAAAATTTTTCCCCCTCCATC
TGTCCCAAATCGGGTAGCGATGAGCTGCTATAGAATTTTCTATTTAAACATGTTTGATAA
GCCCAATTTCCGTTAGATTTTGTTCCCCCTTCGCAGTTTGGTTTGCCGTAACTTTTTTAT
TTTAGTCTCCATCTAGCTGGAGTAATACGATGTAGTGCCTTGTAATCTTTCTTATTTTTA
TATTACCGTTCGTGTTCATTATATCCATTACGTTCCCATA
Chr coordinates
Chr IV from 1270068-1270733