Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SIZ1
Systematic Name
YDR409W
Alias
ULL1
Strain
S288c
Description
SUMO E3 ligase; promotes attachment of small ubiquitin-related modifier sumo (Smt3p) to primarily cytoplasmic proteins; regulates Rsp5p ubiquitin ligase activity and is in turn itself regulated by Rsp5p; required for sumoylation of septins and histone H3 variant Cse4p, a prerequisite for STUbL-mediated Ub-dependent degradation; localizes to the septin ring; acts as an adapter between E2, Ubc9p and substrates; tends to compensate for survival of DNA damage in absence of Nfi1p
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SIZ1 YDR409W
ATGATAAATTTAGAGGATTACTGGGAAGATGAAACGCCTGGGCCTGATAGGGAACCGACT
AATGAACTAAGAAACGAGGTGGAGGAAACCATCACTCTGATGGAACTGCTGAAAGTGTCC
GAATTGAAGGATATTTGCAGGTCTGTATCTTTCCCGGTTTCCGGTCGCAAGGCCGTTCTA
CAGGACCTTATCAGGAATTTCTTGCAGAACGCTTTAGTAGTAGGCAAGTCTGATCCTTAT
AGAGTTCAAGCCGTTAAATTTCTGATAGAACGGATCAGAAAGAATGAACCTTTGCCTGTT
TATAAAGATCTTTGGAACGCTTTAAGAAAGGGTACCCCATTGAGTGCTATCACAGTACGT
TCTATGGAGGGGCCTCCCACGGTGCAGCAGCAATCACCTTCCGTTATTAGGCAGTCTCCC
ACTCAACGGCGGAAAACGTCTACCACATCTTCCACATCTCGTGCACCACCACCTACAAAT
CCAGATGCCTCTTCTTCTTCATCATCTTTTGCTGTACCGACAATTCATTTTAAAGAGTCT
CCATTTTACAAAATACAAAGGCTAATCCCTGAATTAGTGATGAACGTGGAAGTCACAGGC
GGAAGAGGTATGTGCTCTGCGAAATTTAAATTGTCCAAAGCAGACTATAATCTATTAAGT
AACCCGAATAGCAAACACAGGCTATACTTATTTTCTGGGATGATTAATCCATTAGGATCC
CGAGGTAATGAACCCATCCAATTTCCATTCCCAAATGAATTAAGGTGCAATAATGTTCAA
ATCAAAGATAATATAAGAGGTTTCAAGAGTAAGCCGGGCACAGCTAAGCCGGCGGATTTA
ACGCCTCATCTCAAACCTTATACTCAACAAAACAATGTGGAGCTGATATATGCCTTCACC
ACGAAGGAATACAAGCTATTTGGGTACATTGTAGAAATGATCACTCCGGAGCAACTCCTG
GAAAAAGTATTACAGCATCCAAAAATTATTAAACAAGCCACGTTACTTTACTTGAAAAAA
ACACTTCGGGAGGATGAAGAAATGGGCTTGACTACCACATCTACTATCATGAGTCTGCAA
TGTCCAATTTCGTACACAAGAATGAAATACCCTTCAAAATCAATAAATTGTAAGCATCTG
CAATGTTTTGATGCATTATGGTTCCTACACTCCCAACTACAAATTCCTACGTGGCAATGC
CCAGTATGTCAAATTGATATAGCTTTGGAAAATTTAGCAATTTCCGAATTTGTTGATGAC
ATTTTACAGAACTGTCAAAAAAACGTTGAACAGGTAGAACTTACTTCTGATGGTAAGTGG
ACAGCCATATTGGAAGACGATGATGACAGCGACAGTGACAGCAATGATGGTAGTAGAAGC
CCAGAAAAAGGTACTTCAGTATCGGATCATCATTGTTCTTCTTCACATCCAAGTGAACCG
ATTATCATAAATCTCGATAGTGATGATGACGAACCAAATGGAAATAATCCTCATGTTACT
AATAATCATGATGATAGCAACAGGCATAGTAATGATAACAATAATAATAGTATCAAAAAT
AATGATAGTCATAATAAAAATAATAATAATAATAATAATAACAATAATAATAATAATGAT
AATAATAATAGTATCGAAAATAATGATAGTAATAGTAATAATAAACATGATCATGGTAGT
CGCAGTAATACTCCCAGTCATAATCATACTAAAAATTTAATGAACGATAATGATGACGAT
GATGATGATCGACTTATGGCGGAAATAACTAGCAATCACCTTAAAAGTACTAATACAGAT
ATTCTAACTGAAAAAGGTTCAAGTGCACCCTCGAGAACCCTGGATCCAAAAAGTTATAAC
ATAGTTGCTTCAGAAACTACTACTCCGGTGACAAACAGGGTTATTCCTGAGTACCTCGGA
AACAGTTCCAGTTATATTGGTAAACAATTGCCGAACATTCTGGGAAAAACGCCTTTAAAT
GTGACTGCTGTTGATAATTCATCCCACTTAATCTCTCCAGATGTTAGCGTATCATCCCCA
ACGCCAAGAAACACCGCTTCAAATGCAAGTTCGAGCGCTCTCAGTACCCCTCCCTTAATA
AGAATGAGTTCATTAGATCCCAGGGGATCCACTGTTCCCGATAAAACAATAAGGCCTCCC
ATAAATTCCAACAGTTATACTGCATCGATATCAGATTCATTTGTCCAGCCTCAAGAATCT
TCAGTTTTTCCACCACGTGAACAGAATATGGATATGTCCTTTCCTTCCACCGTGAACTCA
AGATTTAATGATCCACGTTTGAATACCACAAGATTCCCTGATTCAACATTGCGTGGGGCA
ACTATTTTGTCGAATAATGGGCTTGATCAAAGGAATAACTCTCTACCAACAACAGAAGCA
ATCACGAGGAATGACGTCGGGCGACAAAATTCTACGCCTGTACTTCCCACGTTGCCCCAG
AACGTCCCAATTCGTACAAACTCTAACAAGTCTGGGCTTCCTTTGATAAACAATGAAAAC
AGTGTCCCCAATCCTCCCAACACTGCAACCATACCGTTGCAGAAGTCCAGACTCATTGTA
AATCCATTCATTCCAAGGAGGCCTTACTCTAATGTACTGCCCCAAAAAAGACAACTTTCT
AATACATCCTCAACTTCACCCATAATGGGTACATGGAAAACGCAAGATTATGGAAAGAAA
TACAACAGTGGTTAA
Promoter Sequence
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>SIZ1 YDR409W
GCTTGTTCTCGTCCTGACATTTGCGCCATGCCATTTCAATTGCGTGTGTGGTACCATCGA
AACAACCTGGTAGCGCTGGATGCAGATTTAATATCGGCACAGATTGCAGTTGGCTCAAGA
AAGTAGATCCAAGGATCAATAACCAGCCCGCGCAGATGATAACGTCAGGCTTTTCCTCGA
GCACTAGTTTTGCGAGGTCGTTCTCAAACTGGGATCTTGCCTTGGCCCTTGCGGCTTTGT
CCTCCTTCGCAATACCCTTTGTATATGGGTATAGCGAACAAACCTTTGTGGGGATATTAT
TGTCCGCTGCCCTAGTTAACCCGTATGCCTTCTTGCTGGAAGATATGACAGAGACAATAT
GAGCATCCTCGCCTAATTGGCCCTGCTTTTGGGCATCGATCAAGGCTTGCAAGTTGGAAC
CTGAGCCCGAAATTAATACGACAATTCTGGCCATAGCTTTTGGAAAGATTATTGATGTGT
GTTGGCTCTCACCTGCGCTTGCTGCAAGTTAAATCATCAACCTTGAGGCTAGGAGCGTTA
TTCAACTTTAGAAGTGTCTTCTCTTCATAAACTACTCTATATAACTTTCCTCTTGCTGGA
ATAAAAAACAGGTCAGAGTCACTAGCAACGAGTCACTCATTCGAATCCTTGCTGACGCTT
TTAGTCTTTATGCTGAAATCTATCTTCGAAGTCGGAAGGAAAATGCATTTTTAAACTATC
ACTAGAACTACCATTTTAGAGCGAGCAGAAGGTTCCTCTTTTCTTAAACAAGTATAATTT
TCCTTTTTGGATTGTACTTTATATTCTTACACTAAACGGCCCCTAGATGTCACCTGAGCT
GTAGTCAATGTATACACCCATTCACCGCACCAGATAGTAAGTTGAAAAGTGTATCATCTT
TAATATGAATATGAAAGAATGAAGTGGAGTTCATCCATATTTCACAAGAAAAGAAGACTC
CAACTCAAACAGTTGAGTGTTCCATATACATTCTGTTTCA
Chr coordinates
Chr IV from 1289406-1292120