Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PKH1
Systematic Name
YDR490C
Strain
S288c
Description
Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PKH1 YDR490C
ATGGGAAATAGGTCTTTGACAGAGGCAGACCACGCCCTGCTGTCCAAGCCCTTGGTACCG
ACATCTGCGGAACATACACAAACGCAAGAGTATCCTCGTCCTTTCGTAGATGGCAGCAAT
TCTCAGAGCGGGTCTGAACTACAGGCTTCTCCACAAGGTCAGTTTGGAGAAAAGGCATTG
ACTAGTACTAATCGCTTCATTCCCCTGGCAAATGATGACCCGGGTATGCAGCACGAGATG
GGTCTTGATCCCTCAATGAGGCGTAGAAGAGAAGAATGGGCAGAACGTGGTGCGGCAAAA
ATCGTCAAAGATGTTGTCGACCCAGCTACGGGGGAGTTAACTAAGCATGTTGTCAAGATG
GGAATAAAGGACTTCAAGTTTGGAGAGCAACTCGGGGATGGATCATATTCTAGTGTTGTT
CTGGCTACCGCCCGTGATTCGGGCAAGAAATATGCAGTAAAAGTGTTGAGTAAAGAATAT
CTGATCCGTCAAAAAAAAGTTAAATACGTCACAGTGGAGAAATTGGCTTTGCAGAAGCTG
AATGGCACCAAGGGCATATTCAAGCTTTTCTTCACTTTCCAGGACGAGGCAAGCTTGTAT
TTCCTTCTAGAATATGCCCCCCACGGTGATTTCTTGGGCTTGATTAAGAAATATGGATCT
TTAAACGAGACATGTGCACGCTATTATGCGTCGCAGATCATCGATGCCGTTGACTCCTTG
CATAATATCGGCATTATTCACAGGGATATCAAGCCCGAAAACATATTGCTCGACAAAAAT
ATGAAAGTGAAGTTGACGGATTTTGGTACAGCCAAAATTTTACCGGAGGAACCTTCGAAC
ACCGCAGATGGCAAGCCTTATTTCGATTTGTATGCTAAGTCGAAATCATTTGTTGGTACC
GCAGAATATGTTTCTCCTGAGCTACTGAATGATAATTATACAGATTCCCGTTGTGACATT
TGGGCATTTGGTTGCATATTGTACCAAATGCTTGCGGGAAAACCGCCTTTTAAAGCTGCC
AATGAATATTTGACATTCCAAAAAGTAATGAAGATTCAATATGCGTTTACTGCAGGTTTT
CCGCAAATAGTAAAAGATTTAGTTAAAAAACTATTAGTTAGGGATCCAAATGATAGATTG
ACCATAAAGCAGATCAAAGCACACCTCTTTTTCCATGAAGTCAACTTTGAAGATGGTTCT
GTTTGGGATGATAATCCACCGGAGATACAGCCATATAAAATAAATGCAGAGGCGATGAAG
CCCCTGCAAAAGGTTTCTGAATCTGATACCACTGTCAAAATGGCCAACCTTCAGCTGGCT
GGTAATGGACATGCAGATACTCCCCTGCAAGCACCAGCAGCGACCTCTCAAGAGCATTCT
GTGATCAGTATGACTGCAGCAACCGCCGCATTCAATAAAGATTATACAAGTCAACCCAAA
TTGGGGAGCAAGTCAAGCACATCTGTTAGATCTGCCTCCAACAACACAGATCGCGAGGTA
ATTCAAAAGAAGGTTTCAAAAAATCGCGCATCTGTATCATCTCCTTCAATTTCTACTACA
TCACGGGGGAAAGATAATAGAAGTCGCTCTTCTGACGCCTTCTGGTCACGCTACTTGCAA
AATATGGATGAACGTGTCTTGTTGATGAAGGAGGTAGCGCTTTCCACACGAAACTTAGAG
GACTCACCTGTAGGTCTTGAGAACGTGGCTCTGGACTACAAGAACCCTCTTGATATCGAG
CCTCCTACTGATAGTGCAGGCAAATTTTACAAGAAAATGTTTCTAATAACAAACCTAGGC
AGAGCACTTGTTTTTGTCAAGAGAAGAAGTCTCAGCATGTGGGAAGAACAGGAATTTGAA
TTGCAATTCGAACTAGAGTTGAATGACGTTGAGAAGATACGCTTTATAAGTGATCAAGTC
CTTGAAATTGACGGTTCCAGGACGATTTTCATAGGATGCAAAGAGAGAGCAGTTTTAATG
AAACTATGGAAATTAATACATAATGGAATGACCGCCAAACCTAAAGTAGTATCGCCGAAG
TCGGACCATAAAATGTTTGATAAGTTCATTCTTCAAAAAAGACAGAATACAAAAAAAAAG
AATCAAGCTCCTCCCGTACCTCAATCGAATAGGCTAATAAATGGTTTACCGGACCGTTGC
ATCTTAAAGACACCCGAAGAAGGCGCACTTCACACAAAACGTCCCACTTCGTTGCAGACC
CGATCGTCATCTAATTACTCAAAATTGCTGGCAAGATCGACACAAATGCGGAAAAACATG
ACACGGACAGATGAAAAATGA
Promoter Sequence
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>PKH1 YDR490C
CCAGGAAGTGGAGGGGAAAACGGGAATTAGAAAGTAGTTGGTCAACGTAATGGCAAACAC
GAAGTATACGATAGCCGGTACCAAATGTGTATAAATGTTCACAGTCTCGTTGTTCCAATA
AAATAAAGAATATAAGCACTTTTTCCATGACAGTGTTTCACGAACGTACCCGGTGAGAAT
TTTGTCATTATCTTTTTGCCATTCTGGCAACTCATCGAAATTGTGTAGCAGTTTTTGCTT
TTCAAAAACTGTCTGGCCTGAGACAGCTTCCACCTTAATGGAGGCTCTCGTTGCCTTGCA
GCAGACACTATCTTGGTTTCTTCTTCTAGTAGTGGTGATACTCATTTTTTTTCTTCTTTT
ATCTTGCTTGACTCAATTAAGGCGACTAATAACAAAACGAATGACGAAAATGGAAAACAA
TAGAAAAGTTAGGAACCAGAATCACTTTTGTAAAGTTAATATTGCGCTTGCGGAGCTCCT
TACTGTTTCAACTGATGATACTGATATGCCTTTAGAAAAGAAATCAAATTCTATTAACAG
AAGGGTGCCAACATGTACGTATATATATATGTGTGCGTGTGTATATATGTCTGACATATA
CATGAGTAACCGGCTAAGTAAGGTTTTTACGTTGATTGCTGCATCCATCGGTCGTGAGTA
TTGTCAAATTGCCGATGCCCTGCAGGCAAAAAAACCGTTGAAAAATCGTTGGGAAAATGG
GCTTGCCCGACTGTCGGATTTAAGGGCTTGGACCCTAAAGGTTGCATGATAAGACCTACT
TATTTTAGCATATAACCCTATAAAGGTGAAAATCTCAGTAGGGTTATTTTCGTTTAAGGG
AGCATGAAAAATTCAAGTTAGTACATATTAATGGCTTTGAGATATTGCGGAGTGACAACA
AGAGTAATACAGAGCAGGCGAGAAAGTAACGCTGGACAGTCACTATCTGGTACAACTTGC
GCACGTGTACTTGCTTGAATACTGCTACTATATCATTAAT
Chr coordinates
Chr IV from 1434268-1431968