Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MMS21 Systematic Name
YEL019C Alias
NSE2, PSO10 Strain
S288c Description
Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex; required for anchoring dsDNA breaks to the nuclear periphery; SMC5-SMC6 plays a key role in removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; required for efficient sister chromatid cohesion; mutants are sensitive to MMS, show increased spontaneous mutation and mitotic recombination; SUMOylates and inhibits Snf1p function; supports nucleolar function External sources
Open in SGD
Open in KEGG
Gene Sequence
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>MMS21 YEL019C
ATGGCCTTGAACGATAATCCTATACCCAAGTCAGTTCCTCTACACCCAAAATCAGGTAAG
TACTTCCATAATTTACATGCCCGAGACTTATCAAATATATATCAACAATGCTACAAACAA
ATTGATGAGACCATAAATCAATTAGTGGATTCTACATCTCCTTCCACCATCGGCATTGAA
GAGCAGGTCGCAGATATTACTAGCACCTACAAACTCCTCTCGACATACGAATCGGAATCC
AACTCATTTGACGAACATATTAAAGATTTAAAAAAAAATTTCAAACAATCCTCAGATGCC
TGTCCGCAAATCGACCTTTCTACCTGGGATAAATATCGTACCGGAGAACTCACCGCTCCC
AAATTATCTGAATTATATCTAAATATGCCCACACCAGAGCCTGCAACCATGGTTAATAAC
ACAGATACACTCAAGATACTAAAAGTGTTGCCGTACATATGGAATGATCCAACTTGTGTA
ATACCGGATCTGCAAAACCCCGCAGACGAAGACGATCTACAAATAGAAGGTGGTAAAATT
GAATTGACTTGTCCTATCACCTGCAAACCTTACGAAGCACCATTGATATCAAGAAAATGT
AATCACGTCTTCGATAGAGACGGCATTCAAAACTATTTACAAGGATACACGACAAGAGAT
TGCCCGCAAGCAGCGTGTTCTCAAGTCGTTTCAATGAGGGATTTTGTAAGAGACCCTATT
ATGGAACTAAGGTGTAAGATCGCCAAGATGAAAGAATCTCAGGAACAGGATAAAAGAAGT
AGTCAAGCCATCGATGTTTTATGA Promoter Sequence
Download FASTA
>MMS21 YEL019C
TGCTCTTCTCATGAACTGCACCGTATCATCCAATTCAAACTGCACTTGTCTAGCCAATTT
CCAGTCGTCCGTACCAATGACCTTTCGCATTACACCGTCCGTTATGCTCTTTTGAAGAAT
CAGCTGCAGTTCATGAACGCTGCCGGGCGTTTCGTTCTTTATGTCTTCGTAATTTATCTC
ATTCTTGATAATGCTACCATCGGGACTCTTGAATAGCTTCTGAAAATTCCCAGTTTTACT
TTCCAATTTATTCAGAACGGTATCTCTGTATAATTTCAATAGTTTTTCTCTTTTTGGGTC
CATTGAATGCGCCATGTGTGGCGTAGTCGTAGTTATAGTAGCACTGGTACCAGCAGATCC
ACTTTTGCCAGCATTTGCATGTGGTTGCAGTTGCGATGCACCGGTCTTTATACCGTTCTT
CAATATCTCATCCTCCATCATCCTTATTTGTTCGACCTGCGTTTTCTTGAATCGATCGTA
CTTTTCGTCAAGGAGCTTCTCGATATCATGCATTTCCAAACCGTGTAGACTAAGTTGTCC
ATCGTTTAGTGTTGTTCTGTACTCTGGGAATAAATTCTTAACTATGGTCAGGATATCGTT
GATGCCCAGTTTCCTGTTTCCATTTGCCACGTTGCTTTGCCTTCTTAAATTTGTCAGCTC
GTTGATTAGCAAATTGTTTTGTATTTCGTTAGTCAACTTGACTAGCGATATTCGAAGATT
ATTCCCAATCATGTTGATTCCTCCCCCGTTCCTAACCAGTTCTTCATTCTTGTTGGAAAT
TAAAGTGTGTATTAGCTGCAACACTACCAATTCACTTACCTCTTTATCCATCTATGCGTT
CCTTTGATTCTGGTTACTCCGGCACGCAGAAGTATCTTTTTACCAGTGCTTCTCTGGTTA
TTTTCTTCCTCTTTTCCTGTGTAGAAAAAAACTTGCTAAAATAATCGTGTCAGTTAAAGA
AACCAAGGCAAGACTATATAAAAAAAGAATAACTTTAAAA
Chr coordinates
Chr V from 121301-120498
