Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name PRB1
Systematic Name YEL060C
Alias CVT1
Strain S288c
Description Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity; serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation; activity inhibited by Pbi2p; protein abundance increases in response to DNA replication stress; PRB1 has a paralog, YSP3, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>PRB1 YEL060C
ATGAAGTTAGAAAATACTCTATTTACACTCGGTGCCCTAGGGAGCATCTCTGCTGCTTTG
GTCATCCCAAATCTTGAAAATGCCGCCGACCACCACGAACTGATTAACAAGGAAGATCAC
CACGAGAGACCCAGAAAAGTGGAATTCACTAAGGACGATGATGAGGAGCCATCTGACTCT
GAAGATAAAGAACATGGAAAGTTCCATAAGAAGGGCCGCAAGGGCCAAGACAAGGAGTCT
CCGGAATTCAACGGTAAACGTGCAAGTGGCTCTCATGGGAGCGCCCACGAGGGAGGAAAG
GGCATGAAGCCTAAGCATGAAAGTTCCAATGATGATGATAATGATGATAAGAAGAAGAAG
CCTCACCATAAGGGTGGCTGCCACGAAAATAAGGTGGAGGAGAAGAAGATGAAAGGTAAG
AAAGTCAAGGGCAAGAAGCACCACGAAAAGACGTTGGAGAAAGGGAGGCACCACAACAGG
CTGGCTCCTCTCGTGTCCACTGCACAATTCAACCCAGACGCGATCTCCAAGATCATCCCC
AACCGCTACATTATAGTCTTCAAGAGAGGTGCCCCTCAAGAAGAGATCGATTTCCACAAG
GAAAACGTCCAGCAGGCACAACTTCAATCCGTAGAGAACTTATCTGCCGAAGACGCTTTC
TTCATTTCTACTAAAGACACCTCCTTGTCCACCTCTGAGGCTGGCGGTATCCAGGACTCA
TTCAACATCGATAATCTTTTCTCCGGTTACATCGGTTACTTCACCCAAGAGATTGTCGAC
TTGATACGTCAAAACCCATTAGTAGACTTTGTTGAGAGAGACTCTATTGTCGAGGCTACA
GAATTTGACACTCAAAATAGCGCCCCATGGGGGTTGGCCCGTATTTCCCACAGAGAGCGC
CTCAACCTGGGGTCCTTCAACAAGTATCTCTACGATGATGATGCCGGTCGCGGTGTCACG
TCCTATGTTATTGACACGGGTGTCAACATCAACCACAAGGACTTCGAAAAGAGAGCCATT
TGGGGGAAAACCATCCCACTTAACGACGAAGATCTCGACGGTAACGGCCACGGTACCCAC
TGTGCCGGTACTATCGCTTCCAAACACTACGGTGTCGCTAAAAATGCCAACGTTGTTGCG
GTGAAAGTCTTGAGATCAAACGGGTCTGGTACCATGTCTGATGTCGTCAAAGGTGTCGAA
TATGCCGCAAAGGCGCACCAAAAAGAAGCCCAAGAAAAGAAAAAGGGGTTCAAAGGTTCC
ACAGCCAATATGTCGCTTGGTGGTGGCAAGTCCCCAGCTTTGGACTTGGCTGTTAATGCA
GCCGTTGAAGTCGGTATTCACTTTGCCGTGGCTGCTGGTAACGAAAACCAAGACGCTTGT
AATACCTCCCCAGCTTCTGCTGACAAGGCCATCACCGTCGGAGCTTCCACGTTGAGCGAT
GACAGAGCCTACTTTTCCAACTGGGGTAAGTGTGTCGACGTTTTCGCCCCAGGTTTAAAC
ATTTTGTCCACCTACATTGGAAGTGATGACGCCACCGCCACTTTATCGGGTACCTCAATG
GCTTCCCCTCACGTTGCTGGTTTGTTGACCTACTTTTTGTCTTTGCAACCAGGTTCTGAT
AGTGAATTTTTCGAATTGGGCCAGGATTCTTTGACTCCTCAGCAATTGAAAAAGAAGCTA
ATTCATTACAGTACAAAGGACATTTTGTTCGATATCCCTGAAGACACTCCAAATGTTTTA
ATCTACAACGGTGGTGGTCAAGATTTGTCCGCTTTCTGGAATGATACCAAAAAGTCCCAT
TCATCTGGTTTCAAGCAAGAATTGAACATGGATGAATTCATTGGATCAAAGACCGATTTA
ATCTTTGATCAAGTGAGAGATATTCTTGATAAATTGAATATTATTTAA
Promoter Sequence
Download FASTA
>PRB1 YEL060C
TAGGCTGTGCCGACATGCCATTTTATGCGGCTCACTTCTAACAAAAGTGACCATGACGCA
CAAGCAAGCAAACAGCCAAGTAAGGAAGCAGACAGCTTCACAGCACACACACACCGTTGT
GTACGAAAATCCTCTGCAGAAGAGTGTATATGCCACTCATCCACACTTCCGCAGCGCAGT
ACGTAATGCGGTATCGTGAAAGCGAAAAAAAAACTAACAGTAGATAAGACAGATAGACAG
ATAGAGATGGACGAGAAACAGGGGGGGAGAAAAGGGGAAAAGAGAAGGAAAGAAAGACTC
ATCTATCGCAGATAAGACAATCAACCCTCATGGCGCCTCCAACCACCATCCGCACTAGGG
ACCAAGCGCTCGCACCGTTAGCAACGCTTGACTCACAAACCAACTGCCGGCTGAAAGAGC
TTGTGCAATGGGAGTGCCAATTCAAAGGAGCCGAATACGTCTGCTCGCCTTTTAAGAGGC
TTTTTGAACACTGCATTGCACCCGACAAATCAGCCACTAACTACGAGGTCACGGACACAT
ATACCAATAGTTAAAAATTACATATACTCTATATAGCACAGTAGTGTGATAAATAAAAAA
TTTTGCCAAGACTTTTTTAAACTGCACCCGACAGATCAGGTCTGTGCCTACTATGCACTT
ATGCCCGGGGTCCCGGGAGGAGAAAAAACGAGGGCTGGGAAATGTCCGTGGACTTTAAAC
GCTCCGGGTTAGCAGAGTAGCAGGGCTTTCGGCTTTGGAAATTTAGGTGACTTGTTGAAA
AAGCAAAATTTGGGCTCAGTAATGCCACTGCAGTGGCTTATCACGCCAGGACTGCGGGAG
TGGCGGGGGCAAACACACCCGCGATAAAGAGCGCGATGAATATAAAAGGGGGCCAATGTT
ACGTCCCGTTATATTGGAGTTCTTCCCATACAAACTTAAGAGTCCAATTAGCTTCATCGC
CAATAAAAAAACAAACTAAACCTAATTCTAACAAGCAAAG
Chr coordinates Chr V from 41953-40046
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