Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PRB1
Systematic Name
YEL060C
Alias
CVT1
Strain
S288c
Description
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity; serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation; activity inhibited by Pbi2p; protein abundance increases in response to DNA replication stress; PRB1 has a paralog, YSP3, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PRB1 YEL060C
ATGAAGTTAGAAAATACTCTATTTACACTCGGTGCCCTAGGGAGCATCTCTGCTGCTTTG
GTCATCCCAAATCTTGAAAATGCCGCCGACCACCACGAACTGATTAACAAGGAAGATCAC
CACGAGAGACCCAGAAAAGTGGAATTCACTAAGGACGATGATGAGGAGCCATCTGACTCT
GAAGATAAAGAACATGGAAAGTTCCATAAGAAGGGCCGCAAGGGCCAAGACAAGGAGTCT
CCGGAATTCAACGGTAAACGTGCAAGTGGCTCTCATGGGAGCGCCCACGAGGGAGGAAAG
GGCATGAAGCCTAAGCATGAAAGTTCCAATGATGATGATAATGATGATAAGAAGAAGAAG
CCTCACCATAAGGGTGGCTGCCACGAAAATAAGGTGGAGGAGAAGAAGATGAAAGGTAAG
AAAGTCAAGGGCAAGAAGCACCACGAAAAGACGTTGGAGAAAGGGAGGCACCACAACAGG
CTGGCTCCTCTCGTGTCCACTGCACAATTCAACCCAGACGCGATCTCCAAGATCATCCCC
AACCGCTACATTATAGTCTTCAAGAGAGGTGCCCCTCAAGAAGAGATCGATTTCCACAAG
GAAAACGTCCAGCAGGCACAACTTCAATCCGTAGAGAACTTATCTGCCGAAGACGCTTTC
TTCATTTCTACTAAAGACACCTCCTTGTCCACCTCTGAGGCTGGCGGTATCCAGGACTCA
TTCAACATCGATAATCTTTTCTCCGGTTACATCGGTTACTTCACCCAAGAGATTGTCGAC
TTGATACGTCAAAACCCATTAGTAGACTTTGTTGAGAGAGACTCTATTGTCGAGGCTACA
GAATTTGACACTCAAAATAGCGCCCCATGGGGGTTGGCCCGTATTTCCCACAGAGAGCGC
CTCAACCTGGGGTCCTTCAACAAGTATCTCTACGATGATGATGCCGGTCGCGGTGTCACG
TCCTATGTTATTGACACGGGTGTCAACATCAACCACAAGGACTTCGAAAAGAGAGCCATT
TGGGGGAAAACCATCCCACTTAACGACGAAGATCTCGACGGTAACGGCCACGGTACCCAC
TGTGCCGGTACTATCGCTTCCAAACACTACGGTGTCGCTAAAAATGCCAACGTTGTTGCG
GTGAAAGTCTTGAGATCAAACGGGTCTGGTACCATGTCTGATGTCGTCAAAGGTGTCGAA
TATGCCGCAAAGGCGCACCAAAAAGAAGCCCAAGAAAAGAAAAAGGGGTTCAAAGGTTCC
ACAGCCAATATGTCGCTTGGTGGTGGCAAGTCCCCAGCTTTGGACTTGGCTGTTAATGCA
GCCGTTGAAGTCGGTATTCACTTTGCCGTGGCTGCTGGTAACGAAAACCAAGACGCTTGT
AATACCTCCCCAGCTTCTGCTGACAAGGCCATCACCGTCGGAGCTTCCACGTTGAGCGAT
GACAGAGCCTACTTTTCCAACTGGGGTAAGTGTGTCGACGTTTTCGCCCCAGGTTTAAAC
ATTTTGTCCACCTACATTGGAAGTGATGACGCCACCGCCACTTTATCGGGTACCTCAATG
GCTTCCCCTCACGTTGCTGGTTTGTTGACCTACTTTTTGTCTTTGCAACCAGGTTCTGAT
AGTGAATTTTTCGAATTGGGCCAGGATTCTTTGACTCCTCAGCAATTGAAAAAGAAGCTA
ATTCATTACAGTACAAAGGACATTTTGTTCGATATCCCTGAAGACACTCCAAATGTTTTA
ATCTACAACGGTGGTGGTCAAGATTTGTCCGCTTTCTGGAATGATACCAAAAAGTCCCAT
TCATCTGGTTTCAAGCAAGAATTGAACATGGATGAATTCATTGGATCAAAGACCGATTTA
ATCTTTGATCAAGTGAGAGATATTCTTGATAAATTGAATATTATTTAA
Promoter Sequence
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>PRB1 YEL060C
TAGGCTGTGCCGACATGCCATTTTATGCGGCTCACTTCTAACAAAAGTGACCATGACGCA
CAAGCAAGCAAACAGCCAAGTAAGGAAGCAGACAGCTTCACAGCACACACACACCGTTGT
GTACGAAAATCCTCTGCAGAAGAGTGTATATGCCACTCATCCACACTTCCGCAGCGCAGT
ACGTAATGCGGTATCGTGAAAGCGAAAAAAAAACTAACAGTAGATAAGACAGATAGACAG
ATAGAGATGGACGAGAAACAGGGGGGGAGAAAAGGGGAAAAGAGAAGGAAAGAAAGACTC
ATCTATCGCAGATAAGACAATCAACCCTCATGGCGCCTCCAACCACCATCCGCACTAGGG
ACCAAGCGCTCGCACCGTTAGCAACGCTTGACTCACAAACCAACTGCCGGCTGAAAGAGC
TTGTGCAATGGGAGTGCCAATTCAAAGGAGCCGAATACGTCTGCTCGCCTTTTAAGAGGC
TTTTTGAACACTGCATTGCACCCGACAAATCAGCCACTAACTACGAGGTCACGGACACAT
ATACCAATAGTTAAAAATTACATATACTCTATATAGCACAGTAGTGTGATAAATAAAAAA
TTTTGCCAAGACTTTTTTAAACTGCACCCGACAGATCAGGTCTGTGCCTACTATGCACTT
ATGCCCGGGGTCCCGGGAGGAGAAAAAACGAGGGCTGGGAAATGTCCGTGGACTTTAAAC
GCTCCGGGTTAGCAGAGTAGCAGGGCTTTCGGCTTTGGAAATTTAGGTGACTTGTTGAAA
AAGCAAAATTTGGGCTCAGTAATGCCACTGCAGTGGCTTATCACGCCAGGACTGCGGGAG
TGGCGGGGGCAAACACACCCGCGATAAAGAGCGCGATGAATATAAAAGGGGGCCAATGTT
ACGTCCCGTTATATTGGAGTTCTTCCCATACAAACTTAAGAGTCCAATTAGCTTCATCGC
CAATAAAAAAACAAACTAAACCTAATTCTAACAAGCAAAG
Chr coordinates
Chr V from 41953-40046