Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
AFG3
Systematic Name
YER017C
Alias
YTA10
Strain
S288c
Description
Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; involved in cytoplasmic mRNA translation and aging; expression of human homolog AFG3L2 can complement yeast yta12 afg3 double mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA
Hide Seq
>AFG3 YER017C
ATGATGATGTGGCAACGATATGCAAGGGGTGCGCCACGCTCATTGACATCACTCTCATTT
GGTAAAGCTAGCCGCATATCAACAGTGAAGCCAGTGCTTCGCTCGCGCATGCCAGTTCAC
CAGCGTTTGCAGACGTTATCTGGTCTGGCAACCAGAAACACAATACACCGTTCTACCCAA
ATACGTTCCTTCCATATCTCATGGACAAGGTTAAATGAAAATAGGCCAAACAAAGAGGGT
GAGGGCAAGAACAATGGTAATAAAGATAATAATAGCAATAAAGAAGATGGCAAAGACAAA
AGAAATGAGTTTGGTTCATTATCAGAATACTTCAGATCTAAGGAATTTGCTAATACGATG
TTTTTGACCATCGGATTCACAATTATATTTACTTTGCTCACACCTTCCAGTAACAACTCA
GGAGACGACTCTAACCGCGTCTTGACTTTCCAGGATTTCAAAACAAAATACCTGGAGAAG
GGTCTTGTGTCCAAGATTTACGTCGTTAATAAGTTTCTCGTAGAGGCCGAATTAGTCAAT
ACAAAGCAAGTTGTATCGTTCACCATTGGTTCAGTAGATATTTTTGAGGAACAGATGGAC
CAGATCCAGGACCTCTTGAACATTCCTCCTCGGGATCGTATCCCCATCAAATACATTGAG
AGATCTTCTCCCTTCACATTTTTGTTCCCCTTCCTGCCCACCATCATTCTGCTTGGTGGC
CTTTACTTCATAACCAGAAAAATAAATAGTTCACCACCAAATGCCAATGGTGGTGGTGGA
GGAGGCCTCGGCGGCATGTTTAATGTTGGAAAATCCAGAGCAAAGCTCTTCAATAAGGAA
ACAGACATTAAAATTTCATTTAAAAATGTTGCCGGTTGTGATGAAGCTAAACAGGAAATC
ATGGAATTTGTTCACTTTTTGAAGAACCCAGGTAAGTACACTAAATTGGGTGCCAAGATT
CCACGAGGCGCTATTCTTTCTGGACCCCCAGGTACCGGTAAGACTCTCTTGGCCAAGGCC
ACCGCAGGTGAGGCGAACGTGCCCTTCTTGTCAGTATCAGGTTCTGAGTTCGTCGAAATG
TTCGTTGGGGTGGGTGCTTCACGTGTAAGAGACTTGTTTACTCAAGCAAGGTCTATGGCC
CCCTCGATTATCTTTATAGATGAAATTGACGCTATCGGTAAAGAAAGAGGCAAAGGCGGC
GCTCTCGGTGGCGCTAACGATGAAAGAGAAGCTACGCTGAATCAATTATTGGTGGAAATG
GACGGATTCACTACTTCCGACCAAGTCGTAGTCCTTGCGGGTACAAATAGGCCCGATGTG
TTGGATAATGCTTTGATGAGACCGGGAAGGTTCGATAGACATATCCAAATTGATTCTCCT
GATGTCAATGGTAGGCAGCAAATATACCTGGTTCACTTGAAAAGACTGAATCTGGATCCC
CTTCTTACAGATGATATGAATAATCTTTCTGGGAAATTGGCTACGCTTACTCCAGGTTTT
ACTGGTGCAGATATCGCTAATGCTTGTAATGAGGCTGCATTAATCGCTGCCAGACATAAT
GACCCATATATCACTATCCATCACTTTGAGCAAGCCATTGAAAGAGTCATTGCGGGACTA
GAGAAGAAAACAAGAGTCCTTTCTAAGGAAGAAAAAAGGTCAGTGGCCTATCATGAGGCA
GGACATGCCGTTTGTGGTTGGTTTCTAAAATATGCGGATCCACTTCTGAAAGTAAGCATC
ATCCCGCGTGGACAAGGTGCTTTAGGCTATGCCCAGTACCTACCACCGGATCAATATTTG
ATATCTGAGGAGCAATTCAGACATAGAATGATCATGGCTCTTGGTGGCCGTGTTTCTGAG
GAGCTACATTTTCCATCGGTGACTAGCGGTGCTCATGATGATTTCAAAAAGGTTACACAG
ATGGCAAATGCCATGGTTACATCCCTAGGAATGTCACCCAAGATTGGCTACCTGTCGTTT
GATCAGAATGATGGAAACTTCAAAGTTAACAAACCCTTCAGTAATAAAACGGCAAGAACC
ATTGATTTAGAAGTTAAATCTATAGTAGATGATGCACACCGAGCTTGTACAGAATTGCTA
ACCAAAAATTTGGACAAAGTCGATCTTGTCGCAAAAGAATTGCTACGTAAGGAAGCAATT
ACTAGAGAAGACATGATTAGATTATTGGGTCCAAGGCCATTCAAGGAAAGGAACGAGGCT
TTTGAAAAATATTTGGATCCAAAGAGCAATACCGAACCGCCTGAGGCACCTGCAGCAACA
AATTAA
Promoter Sequence
Download FASTA
>AFG3 YER017C
TTTTTTTCCCTTTTTACGCGGAAAGCGCAAATTTCCTCGAAGATTTAAGCCAAACCAAAA
TAAATCAAACCAAACCAAAACAAAACAAAAACAAAAACAAAAACAGGCTAAGCCGATTCA
ATTAAAACCGCTCATACGTATACAACACATACACACATACAAGAATGGCCAGCATAGACG
CATTTTCGGACCTTGAGCGCCGGATGGACGGGTTCCAAAAGGACGTGGCCCAGGTACTGG
CACGTCAGCAAAACCACGCGCGCCAACAGCTGCAACAGTTCCAAGCGGAAATGCGTCAAT
TACATAACCAACACCAACATCTCATAGATGAACTGCAACGGCTTGCCACCCAGCGCACCG
CTCTGCAGCAACAAATACATGCGGCCCAACAAGCTACAAATACCACCAGAGAGCAGTGGA
GAAGCTATCACGAGCGTGAATCTGAGTTATCTAGACGGCAGTCGACCTTAGCAGCCCAAT
CGCGCGAGCTGGACTCGCTGCTGCAACAGCGTGGTAAAGAGTGTGTCCAATTACGCGCAC
GTTGGGCTGCGCAGTCGGGTAACGATGCCGCAGAGGTCGCACTGTACGAACGGCTGTTGC
AGCTTCGTGTACTACCCGGAGCCAGCGATGTGCATGACGTACGTTTCGTATTCGGCGATG
ATTCACGCTGCTGGATCGAAGTCGCGATGCACGGAGACCACGTGATCGGAAACTCTCACC
CGGCGCTGGACCCCAAGAGTCGGGCAACACTTGAGCACGTGCTTACCGTCCAGGGCGACC
TCGCGGCATTTTTAGTCGTGGCCCGCGATATGCTTCTGGCATCTTTATAACGCCTTTATA
CGCATCTGTTCAGTTTATTCTGGGCCTATGATTTAGATGAGGAATAAATTGGTTCTTACT
GTCTATACATAACTTTTACAAGGACCCATTCTATATTAAAGGAGATTAACGCAGTCTTCA
AATAAAGGCATCATCCACTTATTTTATAATATACTAAGTG
Chr coordinates
Chr V from 191788-189503