Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SRB4 Systematic Name
YER022W Alias
MED17 Strain
S288c Description
Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for basal RNA polymerase II transcription; homozygosity of the human MED17 L371P mutation is associated with infantile cerebral and cerebellar atrophy with poor myelination External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>SRB4 YER022W
ATGACAACGGAAGATCCAGATTCAAATCACTTAAGTTCCGAAACTGGCATTAAATTGGCA
TTGGACCCGAACTTAATTACATTGGCACTAAGTTCTAATCCAAACTCTAGCCTTCATTCA
CCAACGTCTGATGAACCCGTACCTGAATCTGCAGGAAAAGCAGATACTAGTATTCGACTA
GAAGGTGATGAGTTAGAGAATAAAACTAAGAAAGACAATGATAAGAACTTAAAATTTTTG
AAGAATAAAGATTCTCTAGTCAGTAATCCACACGAAATTTATGGCTCCATGCCGTTGGAG
CAATTGATCCCAATCATCTTAAGACAGCGTGGTCCAGGCTTTAAATTCGTTGATTTAAAT
GAAAAAGAATTGCAAAATGAGATTAAGCAGCTTGGTAGTGATAGTAGTGACGGTCATAAC
AGCGAGAAGAAGGACACTGATGGCGCTGATGAGAATGTACAAATTGGAGAAGATTTCATG
GAAGTGGATTATGAAGATAAAGATAATCCAGTGGATTCACGAAATGAAACAGACCACAAA
ACGAATGAAAATGGCGAGACCGATGATAATATTGAAACGGTAATGACACAGGAACAGTTT
GTTAAAAGAAGGAGGGATATGCTAGAGCATATAAATCTGGCCATGAACGAATCGTCTTTG
GCTTTGGAATTCGTTTCTTTGCTACTGTCGAGTGTTAAAGAGTCTACAGGTATGTCATCA
ATGTCACCATTTCTTAGGAAAGTTGTTAAACCTTCTAGTTTAAACAGTGATAAAATTCCA
TATGTTGCACCTACAAAAAAAGAATATATCGAGTTGGATATATTGAATAAGGGATGGAAG
TTACAAAGTTTAAACGAATCTAAAGATCTCCTACGCGCAAGTTTTAATAAACTGAGTTCC
ATATTACAGAACGAACATGACTATTGGAATAAGATAATGCAGAGTATTAGCAACAAGGAT
GTTATTTTTAAGATTAGGGACAGGACTAGTGGTCAAAAGCTGTTGGCAATTAAGTATGGT
TACGAAGACTCTGGATCTACCTATAAGCATGACAGAGGTATTGCTAATATAAGGAATAAT
ATAGAATCACAAAATTTGGATTTGATACCCCACAGTAGTTCAGTGTTCAAAGGCACTGAT
TTCGTACATTCAGTAAAGAAATTCTTAAGGGTTCGTATCTTCACAAAAATCGAATCAGAA
GATGATTACATATTGAGTGGCGAAAGTGTGATGGATAGGGATAGTGAAAGTGAAGAAGCT
GAAACGAAAGATATCAGAAAGCAAATCCAACTTTTGAAAAAGATCATTTTTGAAAAAGAA
CTGATGTACCAAATAAAGAAAGAATGCGCTTTGTTGATTTCCTATGGTGTCAGTATTGAA
AACGAAAACAAGGTAATAATTGAACTACCTAACGAAAAATTTGAAATCGAGTTGTTGTCC
CTTGACGATGACTCCATTGTCAATCATGAACAAGACTTACCAAAAATCAACGACAAGAGA
GCAAATTTAATGCTTGTTATGTTGAGACTATTATTAGTCGTTATATTCAAGAAAACATTA
CGATCGAGAATAAGCTCACCCCACGGACTGATCAATTTGAATGTTGACGATGATATCTTA
ATAATACGTCCCATTCTTGGTAAAGTTCGGTTTGCTAATTACAAACTGTTACTAAAAAAA
ATCATAAAGGATTACGTGCTCGATATAGTTCCTGGCTCAAGTATAACAGAAACGGAAGTT
GAGAGAGAACAACCTCAAGAAAATAAAAACATTGATGATGAAAATATAACTAAATTAAAT
AAAGAGATCCGTGCCTTCGATAAACTATTGAATATACCTAGACGTGAACTCAAAATAAAT
CTACCATTAACTGAGCACAAAAGCCCTAATCTAAGTTTAATGCTCGAAAGTCCTAACTAT
TGTAACGCACTCATTCACATCAAGTTTTCAGCTGGTACGGAAGCCAACGCAGTGTCCTTT
GACACAACATTTTCTGATTTTAAAGAAGTAGAGGACTTCCTACATTTTATTGTCGCTGAG
TACATCCAGCAAAAGAAGGTGTAA Promoter Sequence
Download FASTA
>SRB4 YER022W
GCGAACGAGTACATTATTGCAGCCATAAGAAAAGCCCCACATAATTCCAAGAGTTTAGGG
TTCTTACAGCAATCAAACAAACTGCATTGTTGTATTCAATTACTCATGGGTGATATTCCA
GAATTATCATTTTTCCATCAATCAAATATGCAGAAATCTCTCCTTCCTTATTACCATTTG
ACCAAAGCCGTTAAATTAGGTGACTTGAAAAAATTCACATCTACAATCACAAAGTATAAG
CAGTTGCTATTGAAGGATGACACCTATCAACTCTGTGTTAGATTAAGATCTAATGTTATC
AAGACAGGTATCAGGATCATCTCCTTAACGTATAAAAAAATTTCATTAAGAGATATTTGT
TTGAAACTGAATTTGGATTCGGAGCAAACTGTAGAATACATGGTTTCAAGGGCTATTAGA
GATGGTGTTATTGAAGCCAAGATTAATCACGAGGATGGCTTTATCGAAACCACAGAATTA
CTAAACATTTATGATAGTGAAGATCCTCAGCAAGTATTTGATGAAAGAATCAAATTTGCC
AACCAATTACATGATGAATACCTTGTTTCAATGAGGTACCCTGAGGATAAAAAGACTCAA
CAAAATGAGAAAAGTGAAAATGGTGAAAATGATGATGATACGCTAGATGGTGATTTGATG
GATGACATGTCTGATATCTCGGATCTCGACGATTTGGGATTCTTATAAGGGCGCATAAAA
AATAAATAACTACCATTCATAACAGAAATTCATTCGTATATACATAAAGTTCTCATAAAC
GTATATATATATATATATATATACTTATTGATATCAAAGTGTGTTACTTTCTACATTCAT
AGACGGGGAAGAAAAGTGAGGAAAAGTTGTTTTCTCTTGTGCACTGCAGCCCTTTGAAAA
AGTAGAACTGCAGAAAAAATAACTGAACGTAAAGCATTATTTACTTTTCAAAGGCAAAAG
AGATAGAGCCAAAAAAATTGTAAGCAGCTTAAAAGCCATA
Chr coordinates
Chr V from 198812-200875
