Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
TPA1
Systematic Name
YER049W
Strain
S288c
Description
Prolyl hydroxylase; catalyzes oxygen-dependent dihydroxylation of Rps23a/b, a 40S ribosomal decoding center subunit; influences translational termination and regulates translational accuracy; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; disputed role as a oxidative dealkylase repairing DNA methyl-base lesions; poly(rA)-binding protein affecting poly(A) tail length and mRNA stability; Fe(II)/2-oxoglutarate-dependent dioxygenase family member similar to human prolyl 4-hydroxylase OGFOD1
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>TPA1 YER049W
ATGAAGAGAAAAACTGCTGAAGTTAAAGGTGAGAAGGAGAGAAATTCCAAACAAATTTCC
CTCGAAGAGGACAAGATAAAGGGTATGTTCAACCCTAAAATCTGGGACAAGACTTTCCAG
GATGGCTTGAAAAAGGAAATTGAAGACTCTCAGCCTTACAACTGGGGTACTATTCATGAA
TTGGTTAATGACGATCTTCTACGTGCTGTTCGTAAAGAAATAGAAACTGAGATCCATTTC
ACTAAAAAAGAAACCGATATCTATAGAGTCAACCAAAGTGGTGACTTGGCCAATTTGTCT
GGTCTGGACTGGGATGACTTGTCCCGTTTGCCTAATTTGTTCAAGCTGCGCCAGATTCTG
TATTCCAAGCAATATCGAGATTTTTTTGGCTACGTCACCAAAGCTGGTAAATTGTCTGGT
TCTAAGACCGACATGAGCATCAACACTTACACAAAGGGATGTCACTTGTTGACTCATGAT
GACGTTATTGGCTCTAGAAGGATTAGTTTCATTTTATACCTACCAGATCCCGACAGAAAA
TGGAAATCGCATTATGGTGGTGGTCTAAGACTTTTTCCAAGTATTTTACCAAACGTTCCA
CATTCCGATCCATCTGCTAAACTAGTTCCACAGTTCAATCAAATTGCTTTTTTCAAAGTT
TTACCGGGTTTCTCTTTCCACGATGTCGAAGAAGTCAAAGTTGATAAGCACAGATTATCT
ATTCAAGGATGGTACCATATTCCACAAGTTGGCGAAGAAGGTTACATACCTGGTGAAGAA
GAAGCGTGGGTCCGTAACAACACATCCACTTTGGCGCAGATTGAATCTAATGTCCTAGAA
GATTTTGAATTTCCAAAGGACGAGAGAAATATTTTATCATTTCATGAAGTGAAGCACTTT
GAAAAAATGCTCAAGGGCGATGCTGGCGCAAAAACTGATAACACACCTAAAGAATCTATG
ACTAGTGTGATTTCTGATTCGGTTAAGTTGTCTGAAGCCGAGTTCACCTATCTATCTCAA
TACATCTCTCCTGAACATTTAAGCTCGAAAGGTATCGAAAAACTACAAAAGCAGTTTGTT
GAGAACTCTTCTCTACAAATTGAGTCGTTTTTAAATGACGATAAATCAGAATTGTTAAAG
AAGGTTATCAAACAAAAAGAGTTGGAACAGGAATGTCCTTATCATTCAAAAGATGTGAAA
GCTCCGTGGAAAACGGCTATTCCTCCACACAAAGCCCGTTATTTGTACATCGACGGTAAG
GAATACCGTAATTTCCAAACAGAAGCTGATATTCTTGAGGCGCTGAATAACAATGATTTG
CCAAACTTTCAGTTTACTAAGGACGCAATTAAAATTATCTCCGATGCTTCCGGAAATAGT
AGGGAAAACAATTTTGATGCAGAATTAGCGTTGATTGACCTAGCTGTATTTCACAAGAGC
ACAATTTTCAAGAAATACCTAGCTCTTCTAACTTCTTTGTGCCCAGTCAGTGAGCAAATC
CTTATTAGAAGGTTTAGGCCAGGAATGGATTTCACATTGGCCACCAAATGTCGCTTTAAT
GAACTTTTGAAAAGCAATCCAGATATAATCGATGCTGTCTTGGAAGGTACTTTGTGCTTG
ACACCTTCTGCCGGTTGGGAATCCGGAGAGCTTGGTGGTTACGAATTGTACATGATGGAC
GACGACGAAGATAATAAGCAATACTTAAAGGAAGACGTTGAAGACGCTTCTGTTTATCGT
GCGGATGACAGTGGTGATTCAGTATTGATTAATGATCCACCTGCTTGGAATACTTTCAAT
TTGGTCTTGAGAGATGAAAGTGTTTTGGAGTTTGTTAAGTACGTCAGCTGGAGCGCTAAA
TCTAGTAGATGGGATGTCAAAATGAAGTGGGATGTCAAATCATGTGATGAAGATGGTCAG
GAAGATGAAGCGTAA
Promoter Sequence
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>TPA1 YER049W
TTACAGCTCCAACAAGAAGGCAGGTGTTGTCTTTATACAAGGAATTCATCAAGAATGCTA
ATCAATTCAATAATTACAACTTCAGGGAATACTTTTTAAGTAAAACAAGGACTACTTTCA
GAAAGAACATGAATCAGCAAGACCCAAAAGTGTTAATGAACCTATTTAAGGAAGCTAAGA
ACGACTTAGGTGTCTTGAAAAGACAGTCTGTTATTTCTCAGATGTACACATTTGACAGGC
TGGTCGTAGAACCATTGCAAGGAAGAAAACACTAAAACCTGGCCTAACTGGTCATTGCAT
GTAAGAAAGAACTTTCCAGTAATTTTTTCCTTCTCACGTCAGGAAATTCGTATGGTTATA
TCTTATAGAGAGGTGGCCGCCTTTAATTTGGAAAAGATATTATTAGATGATATTCCTAAT
TTTCGACCGATACTTTGCATGGTTGGACTTCAATTAGATCATGTAATTTACTTCCTTAAT
ATCAATAGCATTTCTTTTTTGGTAGAAGATTTTTCTTTTCTTTTCTTTTCTTCAACCCAC
ATGGGACTATAAGAGGAGAGTTTATAGCTTGTATATAAAACGCTATAACTAAAACATAAG
CCCACTCTGAGGTGAGATGTCTTTACGGTATGATAACAAGCTGATGCAATGAGAGATCCT
ATGAATTGCTTGGATTCTTTTACATCAGGCATAAAGTTTCCGAAGTATGCAATAAAATGA
GTATTTGCTTATTTATTGTTTGTATCGGGCGATCTTACACCTACTTTATGTGCGTAATAG
TTGCATCTTCTTTTTTCGGACCATTCCATCGGATAAACTTCTTAGGTAAAAGTGAAAAAA
AAAAAAAATTCGCTTATATATTAATCAAGTCATCACTTGGAAGCCGTTCTCTTCCGTTTA
CAACACGAAGAGCCAACTGTTTTCTTGTGTCATTCTTTAGCACTCTTTCTTTTTATTTTT
ACATTTTTTAATTAAGATCACCAAATATACCGGGAATATA
Chr coordinates
Chr V from 251728-253662