Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name SER3
Systematic Name YER081W
Strain S288c
Description 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase; 3PG dehydrogenase that catalyzes the first step in serine and glycine biosynthesis; also functions as an alpha-ketoglutarate reductase, converting alpha-ketoglutarate to D-2-hydroxyglutarate (D-2HG); localizes to the cytoplasm; SER3 has a paralog, SER33, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>SER3 YER081W
ATGACAAGCATTGACATTAACAACTTACAAAATACCTTTCAACAAGCTATGAATATGAGC
GGCTCCCCAGGCGCTGTTTGTACTTCACCTACGCAATCTTTCATGAATACCGTTCCACAG
CGCTTGAATGCTGTAAAGCACCCAAAAATTTTGAAGCCTTTCTCAACGGGTGATATGAAG
ATTTTACTATTAGAAAACGTTAATCAAACTGCTATTACAATCTTCGAAGAGCAAGGTTAC
CAAGTCGAATTCTATAAATCTTCATTGCCCGAGGAAGAGTTGATCGAAAAGATCAAGGAC
GTTCATGCTATTGGTATCAGATCAAAGACTAGATTAACTTCAAATGTCTTACAACATGCG
AAGAATCTGGTTTGTATTGGTTGTTTCTGTATCGGTACCAACCAAGTTGACTTAGACTAC
GCTACCAGCAGAGGTATTGCTGTTTTCAACTCGCCTTTCTCCAACTCAAGATCAGTAGCA
GAATTGGTCATCGCTGAAATCATTAGTTTAGCAAGACAACTAGGTGATAGATCTATCGAA
TTACATACCGGTACATGGAATAAGGTTGCTGCTAGATGTTGGGAGGTAAGAGGAAAAACT
CTTGGTATTATTGGGTACGGTCACATTGGTTCCCAATTATCAGTTCTTGCAGAAGCTATG
GGTTTGCATGTGTTGTACTACGATATTGTAACTATCATGGCCTTGGGTACTGCCAGACAA
GTTTCTACATTAGATGAATTGTTGAATAAATCTGATTTTGTGACACTACATGTACCAGCT
ACTCCTGAAACTGAAAAAATGTTATCTGCCCCACAATTTGCTGCTATGAAGGATGGCGCT
TATGTTATTAATGCTTCAAGAGGTACTGTCGTGGACATTCCATCTTTGATCCAAGCCGTG
AAAGCCAACAAAATTGCAGGTGCTGCTTTGGATGTTTATCCACATGAACCAGCTAAGAAC
GGTGAAGGTTCATTTAACGATGAGCTAAATAGCTGGACTTCTGAATTAGTTTCATTACCA
AATATCATCTTGACACCACACATTGGTGGCTCTACCGAAGAAGCCCAAAGCTCAATCGGT
ATTGAAGTGGCTACCGCATTGTCCAAATACATCAATGAAGGTAACTCTGTCGGTTCAGTC
AACTTCCCAGAAGTGGCATTGAAATCATTGTCTTACGACCAAGAGAACACTGTGCGTGTG
TTATACATTCACCAAAATGTACCAGGTGTTTTGAAGACCGTCAATGATATTTTATCGAAC
CATAACATCGAAAAGCAATTTTCCGATTCAAATGGTGAAATTGCTTATTTAATGGCTGAT
ATCTCTTCTGTTGACCAAAGCGATATTAAAGATATTTATGAACAACTAAATCAAACCTCT
GCTAAGATCTCAATTAGATTGCTATATTAA
Promoter Sequence
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>SER3 YER081W
AGGATTTGCAAAAATTACACGAAAAGCTAATCTCTACACCATTTGCTGCCACTCAAGGGT
GGATTCCTCAAGATATGTTTGATCAACTATTAAATTCCGGCAGTATTGTTAAGCAAGAGA
ACGGAGACTACACCGTGAAGCAACCTGAAGCTACCAAATAATCTATACTAAAAATGAAAT
ATTTTTTTGTTTTCTTTACCTCATTCAACTGTATAGAACGTTATAACAAAATAATCAAGT
TAAAACCCTTTTTTGTACACAATGGAATCTCTTCCATTTACTAATCAACTTAACAATGCT
GGATTGGATATATTGATAACGTTTTAAAAAGCGTTGCGTGATGTTTGGGTGCAATTGGCG
GAAAAGCGGAACTTTCAAATTTACGATAGGTGGAGATACATCTCCACCTTTCTCCCCATT
ATCTTTGAATTTTCCTCAAATATATAAAGAGAACAACAAATCCATAGAAATGCCATTGTT
TAATCCTGATTATCTACATTGTTTTAGTTTTTTACTCACAATCGAGTAATGCCTTTGTTT
GGCCAAGCTATGTGCAAATATCACAAATTAAAAATTTGGTTAAGCAGTTAGGCTGGACCT
AATATTTTAGAAAAACCTAATTTTTTTTGTGGACCCATTTTCGATATTTACTCACAAATG
GAATTCAAGGGGAACAACTTCGGTCTCAGCACTTTAATTATTCTTCTCGTTCCCACCTAA
TTTCGCAATTTATTGTCCTTGACTTCTACCACGAGAAAAAAATTAAGAAAATGCAACGCT
GCCCGTGCAGGGTTTTCTGAGCGGGATGAAAAAATCAGACAAATATCCAAGTTATGAGTA
ATTACTTTGTTGGAAGGAGGGAGCAGAGGATAAGGAAATTCTTAAAACTGTTATGTATAT
AAAGGAAGAACCATTTCTAGTTATTTCACTTTTTGATACTTGTCAACTATCTTAGTAAAA
ATACAGAACTCTATAAAGAACCACAGAAAAATCGACAGCA
Chr coordinates Chr V from 322686-324095
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