Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
DOT6
Systematic Name
YER088C
Alias
PBF2
Strain
S288c
Description
Protein involved in rRNA and ribosome biogenesis; activated in stochastic pulses of nuclear localization; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation; relative distribution to the nucleus increases upon DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>DOT6 YER088C
ATGTCCATTTCAACCAGTTTGAACTCAGCTTCCATTCATTTGAGCAGCATGGACACCCAT
CCTCAGCTACACTCACTCACTCGTCAGCCACACTCGTCGTCAACAGCTATGTCCAAGAAC
GAAGCCCAGGAATCTTCGCCCTCTCTGCCAGCTTCCTCTTCATCGTCGACTTCGGCATCG
GCATCTGCGTCTTCCAAGAATTCGAGCAAGAACCCTTCCTCTTGGGACCCTCAAGATGAT
CTGCTGCTACGTCATTTAAAGGAGGTCAAGAAAATGGGCTGGAAGGATATTTCGCAATAC
TTCCCAAACAGGACTCCTAACGCGTGTCAGTTCAGATGGAGAAGGTTGAAGTCTGGTAAC
TTGAAGTCGAACAAGACTGCTTTGATCGACATCAACACCTATACGGGCCCACTCAAGATC
ACCCACGGCGATGAGACTGCCAACGCTCAGCAAAAGCCCAGCAAGAAGGTAGAAGAAAAC
GTATTAACGGAAGATACTGCTGAGTTCACTACAACGTCATCCATCCCGATTCCCTCCAGA
AAGACCTCGTTGCCTTCGTTTCACGCATCGATGTCATTTTCTCAATCTCCGTCCAATGTG
ACTCCCACTACGATTGTCTCAAACGCTGCTTCTTCCATGCCGTTCGCTCCTCCCACGCTG
CCGGCCGCACTCCCTCATCATCCTCATCAACACCTACACCACCATCCCCATCATAAGACT
CTAAAGCCAAGGTCAAACTCTCACTCCTTCACCAATTCTTTGAACCAAGACCCCATCGTT
CGGTCTAATGATGAGGAGAAGTATGGATTCATTCCTAAAGTATTCGTTAGATCCAGAAGA
AGTTCGTTTGCCTATCCACAACAGGTAGCAATAACCACTACTCCGTCTTCTCCAAACTCT
TCGCATGTCTTACTAAGCTCAAAGTCAAGAAGGGGCTCGCTTGCGAATTGGTCCAGAAGA
TCATCGTTTAATGTTTCAAGTAACAACACTTCAAGACGGTCTTCAATGATTCTTGCACCA
AATTCCGTGTCAAACATATTCAATGTCAACAATAGCGGCAGTAACACTGCTTCTACTTCT
AATACCAACTCAAGAAGGGAATCTGTCATCAAGAAGGAATTTCAGCAAAGATTAAACAAC
TTAAGTAACAGTGGAGGTCCTACCTCCAACAACGGGCCCATTTTCCCCAACTCTTATACC
TTTATGGATCTCCCACATTCTTCATCGGTGTCATCGTCATCCACTTTGCATAAGTCTAAA
CGAGGTTCGTTTTCTGGCCATTCTATGAAGTCATCGTGTAATCCGACTAATCTATGGTCA
AAAGATGAAGACGCTTTGCTAATGGAAAACAAAAAGAGAAACCTATCCGTTATGGAACTA
TCCATTCTTTTGCCGCAGAGAACTGAGGTGGAAATTCAATGGAGATTAAACGCCTTGTCA
AGTGATGCGGATATGTTGTCTCCTACACATTCACCTCAAAAAACTCTGTCCAAGAAAACT
TGTCCAAGAATGTTCAAAAGTGGTTCTACCACTGATGATGACAAAGGTAGCGACAAAGAG
GACGTTATGGGTGATGGTAGTAACGATGATGACGAAGATAATGTAGACCCGCTGCACCGT
GCTAAACAATCCAGTAACAAGACTGTCTTTTCATCCAGCAGTTCCAACATATCCTCCAAA
GACGTTTCACCGGATCCGATCTTTTCACCGGATCCCGCAGATGATTCATCGAATACTTCT
GATGCTGGTTCTAGGTGCACCATAACCTCCGATACCAGCTCCTCGGCTGCAACCATGAAT
CGCACCCCTAATTCCAAAAACCCGCAAGATATTGCTTTGTTAAACAACTTTCGTTCTGAA
GCCATTACTCCGAGACCGAAGCCTTCTTCCACAACTACATCCATCACTACCGAAACCACC
AATAACATGATAAACCACTCTAGTTCTACAACTACTACCACAAACAACAGTCCGCTGCCA
AGCATAAACACTATCTTCAAGGATATGCTGTGA
Promoter Sequence
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>DOT6 YER088C
CTTGACCCTTCCAGCCAATCCAAGAGCAAGACCTCCGGCCCCATTGATCTAGCATCCTTG
GAGGCGCTACTTGGTGCTACAGGAGGAGTGAAGACAGACAGCAACGGGAACAAAGTCACC
TACACTCTTCCCCAGTCTGCCTTGGCCCAACTGCTCCAAACCATGGGCCATGACCCGGCT
TCCTCCCATCCCGAGAATGACAGTAACACTGACCACAAGGCCGGCCGTTCCCACTTGCAA
TGAAGGATCTTCCATCCTTCATTATATATACATACCTATATACGAACCGAACGAACAGAA
AGAGAAGAGAAGACGCAAGACACCACCAGAACCAAGAGCATACACCACTACCACCACCAT
CGCTACCAACAGCAGGATATCCGGATGCAGTTTGACGCTTGAAGATGGTATTCACCTCAG
GGGTAAACGCGCAGAAACTGCGCGTTTACCTGCAGCGACGCCACAAAAACGGACCGGCCC
GGCCAGAGGGTGAGACCAGCAGCGGCCCCGTTGTGAAATCTCACCCCCAGTCCCGGATGG
GCACGAGTCCCCAGCGCCCGTCCCATGAGGTCCTCCTAAGGTAGACAGCGCGGATGTTTC
CGATGCAAAGGAGAAAGGATGGACGGTACAGACATCGTAGACAGGATTCGCGCATTGCCT
TGCACATCTGTGCCCCATCCAATCTACCGTATCTATTGTTATCGTCGTGTGTGCTACTCT
TTTCTCCGACAGCCTCGACAAGACGGAATCAGAAAGTGCACACAGTTTAAAAAGGAAAAA
AACCGAGTACAACAAAAACAGGGACAGGTTTTGAAAAGTGTTCTTTTCTTTGCATCTTCT
CTATTTCTTCTCTCTTTCGTCCTGTTTGGTATCTTGTTGTATTTTTTCTCTCTTTTGTAG
TATATTTATCCGTGTTTCCTCCTTTTCACAGTCAGTTCATCCGACCTCATCGAATAGCTT
CCGTGCACGTTCCAGTCTTCCCTCCCTTCTCTGCTCCGTG
Chr coordinates
Chr V from 335188-333176