Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PTC2
Systematic Name
YER089C
Strain
S288c
Description
Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; inactivates the DNA damage checkpoint; PTC2 has a paralog, PTC3, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PTC2 YER089C
ATGGGACAAATTCTATCAAACCCGGTAATTGATAAAGAGAGCCACTCCGGTGCTGACTCC
TTGACCGCGTTTGGACTGTGTGCAATGCAAGGGTGGCGGATGTCAATGGAGGATTCACAC
ATTCTAGAGCCTAATGTTTTGACAAAGTCCGATAAGGACCATATTGCATTTTACGGTATA
TTCGATGGTCATGGTGGCGCTAAAGTAGCAGAATACTGTGGTAATAAAATAGTGGAGATC
CTGCAAGAGCAGAAATCGTTCCATGAAGGAAATTTACCAAGGGCTTTGATTGATACTTTC
ATAAACACAGACGTGAAACTGTTACAAGATCCTGTGATGAAAGAAGACCATAGCGGATGT
ACGGCTACATCCATATTAGTATCAAAGTCCCAGAACTTGTTAGTATGTGGTAACGCTGGT
GACAGTAGAACCGTACTCGCCACCGACGGGAACGCAAAGGCATTATCATACGATCACAAG
CCCACTCTAGCAAGCGAAAAATCACGTATTGTGGCAGCTGATGGCTTCGTAGAAATGGAT
AGGGTCAACGGTAACTTGGCGCTCTCTCGTGCCATTGGTGATTTTGAGTTCAAATCCAAC
CCCAAATTGGGCCCCGAGGAGCAAATAGTGACATGTGTTCCGGACATTCTCGAGCATTCT
CTAGATTACGATAGGGACGAGTTTGTAATCTTAGCCTGTGATGGTATCTGGGATTGTTTG
ACTTCCCAAGATTGTGTGGACTTGGTTCATCTCGGCCTTCGCGAAGGCAAGACATTGAAT
GAAATTTCTTCGCGGATCATCGATGTCTGTTGTGCTCCCACCACAGAGGGGACGGGTATT
GGATGCGACAACATGAGTATAGTGGTTGTCGCGCTGCTGAAAGAAGGTGAAGACGTCGCT
CAATGGAGCGACCGTATGAAGTCCAAGGCCCACCGCACATCAGTGCGTTCTTTTGCAGAC
AAGAGAAGAAGGGTGTTTAGTTACTACGATTTTTCCAAATGTAACGACGAACAGGTGTTC
GCTATCACTACGAAGAAACCTCAGGACAAATTCACTCGCGACCACGAAGCCGCTGTGGCC
TCGGTGACTGCCGCCGATAACGACGATCCAATGGACATAGACGACACGGACGCTGACACA
GATGCAGAAAATCTTGACCCTTCCAGCCAATCCAAGAGCAAGACCTCCGGCCCCATTGAT
CTAGCATCCTTGGAGGCGCTACTTGGTGCTACAGGAGGAGTGAAGACAGACAGCAACGGG
AACAAAGTCACCTACACTCTTCCCCAGTCTGCCTTGGCCCAACTGCTCCAAACCATGGGC
CATGACCCGGCTTCCTCCCATCCCGAGAATGACAGTAACACTGACCACAAGGCCGGCCGT
TCCCACTTGCAATGA
Promoter Sequence
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>PTC2 YER089C
TAAGAAATATAACCAATAGCACCACCACTTAATTTCGGTAAACCAGGAACATTTTCGGCT
ACTTTAAAGGTAGACATCTCCTTTTCCAAAATTTCCAAAGGATCTGTTTCAATGCCTTCA
GTAGGACCGGTTTTGATGGTCTTGCGTGGCGAGATACCTATGAATGAATAACGATCTAAT
TCATTATTTGTCTTAGCACTTTCCAACAGAAATGATTCCTTTCTATCAGGGTTGTTCAAT
TGTGCCAATTTTAGATATGCCACGTGAGGAGTCAGATCCAATGATGGCAAATACGCATAC
ACGGGATACATATTTATGGAACTATCGTCATTTTGCTGCTGTAATTGCTTTAGAGAGTCA
ATATCCGGTTGAATTTTGATGGAAGCGGTCATTTTTTGCCTTTTTTCCAATCAGAATATC
AGTGCTAATTATCGATTGTGGCCTCGGTTTTAAAGTGATGATTGCCTTCTGCTACGATGG
ACCATAGCCCTTTAGTCATGTTAATATATCAAAATCTAACAATACTTCGATGAGTGAAAA
ATCGTAATGAGTCAGCAAATCACTGTGTACGTTAATGCCTTTAACAACTTTTTTTTTCCC
ACAAACTACTTCAACGATTGAAAGGATTATTCTAAAAAAAAAAATATCATGCTGATAAAT
GGAAGGGGATGGTAAAACAAAGAAAACCAGCCAATTCGGATTCTGACAGAGCAAATTGAA
ACTGGATATTATAGTGCTAAGTATATAGACTTCTGTTTTGTTCTTTAAAACTAAATAAAA
AAAATTCACCCTCCTCCCCACGGAATAAAACTACAACAAGTTCTGTTATCAAGGACAATT
AGTGTATATTAGTTGTTGTAACATTTTTTACTTTCTCTTTTTTTTTTTCATTGATTAATT
ATAACTATTCGTTCGAGATAGTAGTTTTCCGATTAATAACATCCCTAGGATTTTGACTAT
TCCATTGTTGTATAAAATATAGAGAACCAGAAAAAGAAAA
Chr coordinates
Chr V from 337340-335946