Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SLX8
Systematic Name
YER116C
Strain
S288c
Description
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; role in proteolysis of spindle positioning protein Kar9, DNA repair proteins Rad52p and Rad57p; stimulated by SUMO-modified substrates; contains a C-terminal RING domain; forms nuclear foci upon DNA replication stress; required for maintenance of genome integrity like human ortholog RNF
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SLX8 YER116C
ATGGCAAGAAGACCTGATAACCAAAATCCAGAAGGTGAAAATCTACGAATCAAAAGGGTA
AGACTAGAGTCGGTCAGGCAGAACGATGAGGAGGAAGAAAATGAAGTATCGAGAACACAA
AATATCGTCACAGATAACCGCCATGACAGCCCAGAGGCCGTAGTCGAAATCATTGGAGAG
CGAGCTCTTGAGAATACTTCTGAGGAAGATGGTGATGATGATTTATCTCTCTTTAGAGCA
CTTGAAGAAGATCCAGGTAGCGACCATAACACCAGTAACAACGATTCTGGGAATCATGAC
AGGGAAACAATGCATACCGAAGAGCCAGAAGCAAGTTCTGGTAACAATATCACATTAACG
AATAATGTTGAAGAATTGCACACAATGGACGTTCTTTCACAAACAGCAAACACTCCGAGT
GCTTCCCCGATGCTTGACGCAGCACCGCCGACAACGAAACCTGGAACAAATAGTAAGGAA
CAAACTGTTGATTTAACTGCAGATGCCATAGACTTAGACGCTGAAGAGCAACAAGTGTTG
CAAATATCAGATGACGACTTTCAGGAGGAAACCAAAGAAGCACCCAAAGAGTATGGTGCA
GCCAAGGACTATCGCTGCCCGATTTGTTTTGAACCTCCAGAGACAGCCCTCATGACGTTA
TGTGGGCACGTCTTTTGTTGTCCATGCTTATTTCAAATGGTTAATAGCTCAAGAACATGT
AGACAGTTCGGCCATTGCGCTCTTTGTAGAAGTAAAGTGTACTTAAAGGATGTGAGGTTA
ATTATTCTAAGGAAAAAGCAAGTCAAGAAGAAGGTAAAAAGCTAG
Promoter Sequence
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>SLX8 YER116C
GGACATAAATGATCTTACAACAATTGGACATTTTTGGAGTTTGTATATTCCGCATAGAAC
TTCCAATAGTCTTAACAAAAGTAACCTTCTCAGTAATCAGTTGGAAAGGCATCCATTTAA
CGCTTTAAGGCCCAGAAGTAGATTTCGCTATCTGGATGTAGGCATGGAGAAGCCATTAAG
GATAAATTTGGCATCTTCCATTTTGGCTATCCACTATATTCATTGATAGACTCCCACATT
TCTTGAACATTGCTTGTCTCAATTGTAACATTCAGTCTCGGGAATATACTTTTTTATTTG
TTGATTGACGACATCTTGTGTGATTTAAATGGGTATTTCCACTTGTTTCGGTTTTAACAT
ACAGAAATTCTGAATTTTGTACCTTGAGCACCGTTACCTGACATTTTTGCTGTATTATTA
TCGTGATTTCTCGATTATTTCGAAATAGCAATATTACTCGCTTAATCAATATTCAAAATC
TATATACTTCTTGATTATAACTCTCCATCCAACTGAAAAGAAACCGTGGGCTTCCTTCCA
GTAAGTCTCAGAGGCGCAAGCCGGGACAGCACCGTATTAGTTTCAGTTTCCCGCCCAAGT
GAAAGGTAGTTAGCTACTGTCCCTCCCCCGTGCACAGCATGTTGGAGGGTTCCCAGCAGC
TGCCGGTGGGGAAGAGAACAGTAAGCATGAGAGGAACCCTCGCTTTGCCGAGAATTGAAG
GAGACGGCTCCTAATAGAAAAAAATCTTTCAAATTAAACAAAAAATGTTTGGGTTCACAA
AAGTGTACGGATGTATACAACAGGGAAAGAAAGAACTGTTTTCTACATCTATTTGTATTT
TAGGAAATTACAGAAGAGAAGGGATAATATGTCAGATATTAGAGCATGCGGAAGATTAGT
AGGAACAACTTTCTTTCTTCGATCAACAGTACTTTTTCCCCTACTGAGTCAATATAAAGG
GGCGGCCAAGTAACAAACGAGTAAATTAATTACACCTTGT
Chr coordinates
Chr V from 396172-395348