Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name SCS2
Systematic Name YER120W
Strain S288c
Description Integral ER membrane protein, regulates phospholipid metabolism; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane (PM) and regulate PI4P levels by controlling access of Sac1p phosphatase to substrate PI4P in the PM; interacts with FFAT motifs in Opi1p, Swh1p, Osh2p, and Osh3p; involved in telomeric silencing; VAP homolog; SCS2 has a paralog, SCS22, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>SCS2 YER120W
AGATATTGCTATCAGTGGAATCTTCATCACATGCTCGAACCGGCTTGACCTCTGCTCATT
GATTATTGAAAACATATTGTGGTGACATGTGTAGGCAAAGACAAAAATTGGAAGAGTGTT
TAGCACGTTCAAATCATGCGATTGTGGTGGCAGGAGGTAGGAGATCCGGCCTTTCAAGCG
AAGAATCTCATCTGATGGTGCTACATAGTGCAACAACACCAAAACACACAAGTACGCTAC
AGAAGAGATGGCCACCATGGAAGCGTACCTCAACGAATTCAACTTCTTCAGAAAAGACAG
CGGGGCCACGAAAAAAAGCATGATCAGTGAAATTTGCACGTTCCTGTTCAACAGCCAAGC
ATTTCTGGTCCACACAGACATTATTTGGGGCATCAGATCCCCAACTACAATCATATAAGA
GACGCCCACACCAAAACACTTGATAGCGATCGCTAGGTCAAACACAATACCTAGATTTGG
GTTAATCAACCGCGTCAGAGCACTGAACGAGGCCCTCCCCTGTGGTACGTATTTAGCTAC
ACGAGCTTGTATGAACAAGCTTTGCATAGCGCACGCCCCACACAGCACTATCATTATCAC
TCCAGGAATTAATCCAAACGGCTTGAATGCGTACGGCATGGCCAGGATACCAGCACCGCA
CGCCGTGTGTAAAAGTGTCAGCACACCTGATCTAATACTAGCTACCATATGATGCACGAT
TCCTTTCTATGGTTATTGAGCTGTGAAACTAACCCGTCGTTCGACCATTGTTGTTCTATA
TACTTCTAGTTGCTGTATAGATAAGCTCTCCGATCCCCTAAACGTGCGTGGTGATCTTAC
TCTTTCGCCCTCGCTTTTTTTTTTTCGCTTGTTGTTTTCGCAAGGTGAATAGAATGGTTT
TAGTAGCAAAGTGCATTGTTTATTGTGTGGTGTGGTTTGACGCACATTCTGTGTTAATAG
TGTAGCAGAAGGGTATTCTACAATCTCCGCGAACCTAAGT
Chr coordinates Chr V from 401135-401869
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