Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SCS2
Systematic Name
YER120W
Strain
S288c
Description
Integral ER membrane protein, regulates phospholipid metabolism; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane (PM) and regulate PI4P levels by controlling access of Sac1p phosphatase to substrate PI4P in the PM; interacts with FFAT motifs in Opi1p, Swh1p, Osh2p, and Osh3p; involved in telomeric silencing; VAP homolog; SCS2 has a paralog, SCS22, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SCS2 YER120W
ATGTCTGCTGTTGAAATTTCCCCTGACGTGTTGGTGTATAAGTCTCCATTAACGGAGCAA
TCGACAGAATACGCTAGTATTTCCAACAATTCAGACCAAACCATTGCATTTAAGGTCAAG
ACCACAGCCCCAAAGTTTTACTGCGTGAGACCAAACGCCGCAGTTGTTGCTCCAGGTGAA
ACAATCCAGGTTCAAGTTATCTTCCTGGGTTTGACTGAAGAGCCTGCCGCAGACTTTAAG
TGCCGTGACAAGTTCCTGGTTATCACGTTGCCTTCTCCTTACGACCTCAATGGCAAGGCT
GTTGCAGATGTTTGGTCCGACTTGGAGGCTGAGTTCAAGCAACAGGCTATCTCTAAAAAG
ATAAAAGTCAAATATTTGATAAGTCCAGATGTACACCCAGCACAGAACCAAAATATACAG
GAAAACAAGGAAACTGTTGAACCAGTAGTCCAAGACAGTGAGCCAAAGGAAGTGCCTGCT
GTGGTAAACGAAAAGGAGGTCCCTGCTGAACCGGAAACTCAACCTCCCGTCCAAGTAAAG
AAAGAAGAGGTCCCACCTGTCGTTCAGAAAACCGTTCCTCATGAAAATGAGAAGCAAACG
TCCAACAGCACTCCGGCCCCACAGAACCAGATAAAGGAAGCCGCAACCGTACCTGCAGAA
AATGAATCATCCAGCATGGGTATATTCATATTGGTTGCACTCCTTATCTTGGTTTTAGGA
TGGTTCTACAGATAA
Promoter Sequence
Download FASTA
>SCS2 YER120W
AGATATTGCTATCAGTGGAATCTTCATCACATGCTCGAACCGGCTTGACCTCTGCTCATT
GATTATTGAAAACATATTGTGGTGACATGTGTAGGCAAAGACAAAAATTGGAAGAGTGTT
TAGCACGTTCAAATCATGCGATTGTGGTGGCAGGAGGTAGGAGATCCGGCCTTTCAAGCG
AAGAATCTCATCTGATGGTGCTACATAGTGCAACAACACCAAAACACACAAGTACGCTAC
AGAAGAGATGGCCACCATGGAAGCGTACCTCAACGAATTCAACTTCTTCAGAAAAGACAG
CGGGGCCACGAAAAAAAGCATGATCAGTGAAATTTGCACGTTCCTGTTCAACAGCCAAGC
ATTTCTGGTCCACACAGACATTATTTGGGGCATCAGATCCCCAACTACAATCATATAAGA
GACGCCCACACCAAAACACTTGATAGCGATCGCTAGGTCAAACACAATACCTAGATTTGG
GTTAATCAACCGCGTCAGAGCACTGAACGAGGCCCTCCCCTGTGGTACGTATTTAGCTAC
ACGAGCTTGTATGAACAAGCTTTGCATAGCGCACGCCCCACACAGCACTATCATTATCAC
TCCAGGAATTAATCCAAACGGCTTGAATGCGTACGGCATGGCCAGGATACCAGCACCGCA
CGCCGTGTGTAAAAGTGTCAGCACACCTGATCTAATACTAGCTACCATATGATGCACGAT
TCCTTTCTATGGTTATTGAGCTGTGAAACTAACCCGTCGTTCGACCATTGTTGTTCTATA
TACTTCTAGTTGCTGTATAGATAAGCTCTCCGATCCCCTAAACGTGCGTGGTGATCTTAC
TCTTTCGCCCTCGCTTTTTTTTTTTCGCTTGTTGTTTTCGCAAGGTGAATAGAATGGTTT
TAGTAGCAAAGTGCATTGTTTATTGTGTGGTGTGGTTTGACGCACATTCTGTGTTAATAG
TGTAGCAGAAGGGTATTCTACAATCTCCGCGAACCTAAGT
Chr coordinates
Chr V from 401135-401869