Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
RPH1
Systematic Name
YER169W
Alias
KDM4
Strain
S288c
Description
JmjC domain-containing histone demethylase; targets tri- and dimethylated H3K36; associates with actively transcribed regions and promotes elongation; repressor of autophagy-related genes in nutrient-replete conditions; damage-responsive repressor of PHR1; phosphorylated by the Rad53p-dependent DNA damage checkpoint pathway and by a Rim1p-mediated event during starvation; target of stress-induced hormesis; RPH1 has a paralog, GIS1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>RPH1 YER169W
ATGACGAAACTAATCGCTCCTTCAGAAATCGTGGGCGGAGTGCCCGTCTTCAAACCCACA
TACGAGCAATTCGAAGATTTCTATGCATACTGCAAGGCCATAAACAAATATGGCATGAAA
AGTGGTGTTGTGAAAGTAATCCCACCTAAAGAATGGAAAGACAAATTAGATCTGCCTTAT
TCTGCGGAAACGCTCCAAAAGATCAAGATTAAATCACCTATTCAGCAGCATATTTCTGGT
AATAAAGGTCTTTTTATGGTGCAGAACGTGGAGAAAAACAAGACCTATAACATTATACAG
TGGAAAGATCTTTCTAAGGACTATGTGCCTCCGGAGGATCCTAAAGCAAGACGTAATTCT
AGGAAAGGCTCCGTTTCCAAATCCACGAAGTTGAAACTGAAAAATTTTGAATCGTCTTTT
AATATTGATGATTTTGAACAGTTCAGGACGGAGTATACAATAGATTTATCTGACTTCCAA
AATACGGAGAGATTAAAGTTCTTGGAAGAGTATTATTGGAAAACGCTAAATTTTACTACG
CCTATGTACGGCGCAGATACACCAGGATCAATCTTTCCTGAAGGGCTGAACGTTTGGAAT
GTTGCCAAACTACCGAACATCTTGGACCATATGGAAACAAAGGTTCCTGGGGTGAATGAC
TCCTATCTATACGCTGGTCTATGGAAGGCTTCTTTTTCTTGGCACTTGGAAGATCAGGAC
CTGTATTCCATAAATTATATTCATTTCGGTGCCCCAAAACAGTGGTATTCGATACCGCAA
GAGGATAGGTTCAAATTCTACAAATTCATGCAGGAGCAATTTCCCGAAGAAGCCAAAAAT
TGTCCTGAATTTTTAAGACATAAAATGTTTTTGGCTTCGCCCAAACTGCTGCAGGAAAAT
GGCATACGATGCAATGAAATTGTCCACCATGAAGGCGAATTCATGATCACTTATCCCTAT
GGTTACCATGCAGGGTTCAATTATGGATATAACTTGGCAGAATCCGTCAACTTTGCTTTG
GAGGAGTGGCTACCGATTGGGAAGAAAGCTGGAAAATGCCACTGCATTTCAGACTCAGTG
GAAATAGATGTTAAGAAACTCGCTAAATCTTGGAGGGACAATAATAAAGAGTCGAAAGGA
ACGCCACCCCTCAATCAATTACCCAATCCTGCCATGCCCTTACTTCACAGGCCAACTTTA
AAAGAAATGGAAAGCAGCTCGCTTAGATCTACAAGCCCAGATGTGGGTCATTTTTCAAAC
TTTAAATCCAAGAGCTCTGGTGTTTCTTCTCCCTTATTATCACGTATGAAAGATTATTCC
AACATTGTCGAGCCCACACTAGAAGATCCAACTTTGAAATTAAAAAGAATCTCTTCTTTT
CAAGAACAGCCCTTAAACAAACTTTTGAAAAGAGAAACTTCGCAAACGGCGATGCTCACA
GATCACGAAGACAACATAGTGGCCATGAGCCTTACTTCAATGGCAAACAGTGCGGCGTCT
TCTCCGAGGTTGCCACTGTCAAGATTGAATTCATCTAATGAACTCTCAAATGCCCAACCA
TTGCTTGACATGACAAACAATACTCTTGCCTTCCCGCGACCTAATGGACCATCTGGATTG
AACCCTTTATTATATATCTCTAACAAGAATATTAGCGGGATATCTCACTCGGCTCCACAT
TCTCCAGTGAATCCAAATATATCGCTGATAAAACGAGTTAAGTCTCCCAACATTGTAACA
TTAAATATATCCAGGGAATCGTCAAGAAGCCCTATAGCTCTGAATTACGAGGCAAGACAA
CAACATTCGCAACAACATTCATTCTCCACACCATCAACCGTGTCAAATCTCTCTACTTCT
GTGCTCGGGCCACTGAGTGACACAAACGACATAAAAACACCGCACCCTGAAAGACCAAAT
CACAAGACAGCAAATAGAATACTCAAAAAGGAATCTCCTGTCGAGACATCAAAATCAAAT
CTTATACTTTCAAAGGTTGCATCCACTCGCCAAGAGGATTCTTTTACAAGCCGAAATGAC
GATCTGGACAAAGAACAAGGCTCTTCTCCATTAAACTCTAAGTTTGCGCCCGAAGAAATC
GTGTTATCAGGTAAGAACAAGATTTATATTTGTAAGGAATGCCAAAGAAAGTTCTCTTCT
GGTCACCATCTTACAAGACACAAAAAATCCGTCCACTCTGGTGAGAAACCTCATTCTTGT
CCCAAATGTGGCAAAAGATTTAAAAGGAGAGATCACGTTCTGCAGCACTTGAATAAGAAA
ATACCGTGTATTTCAAACGAAACAACAGTAGATGCTCCAATAATGAACCCTACAGTGCAA
CCGCAGGACGGGAAAGCGGCCATTAATCAACAGAGTACACCTTTAAACTGA
Promoter Sequence
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>RPH1 YER169W
ACTCGTTCAAACCAGTAGCAAATTGCTCACCTGACATCACATTGATGGCAATATCCAAGT
CGTGAGAACCTTGTCCCAGAAGCTTGTCACGCACCCATCCGCCCGTGATCCGAAGAGTCA
ATGGCTCAGGCTTATTGTGGTACTTTTGATTGTACAAGTCTGTATAATCGTTCAGCAAGT
TACAGATGTTCTGTTCCACTTTGGTTAAGGTGATTTTGGGTGCATTTAGAACAAAATTAG
AATTCGTCATCGTTTTCTGAGCAGCACTATTCATCAGTAGAGATATAGTAGACCGTAGCA
TACACAAAAAAAGCCCTTATAACCCACGGATACGAATTAATCTCGAGGGAAGCGTTGCGA
TGTATTATGTAGTTTCCTTTAGTACATTGTTAATATGGTAGATTTTTGCGATTCATTTTT
CAACTTTTCAACCCTAACGAATGTTTTTTAGGGCTGAGTAACGACAAGAACACAACCCTA
AAAATCAGATGACCTAAGGGTTTGGTGAATCGAGAAAGTATGCCCTATTTCCCCCGCCCA
TACACCCCATAAGCCTTAACCGCAGCCCTCCTCTCCCCTAAACGTTTCTTTTTCTTTTTC
CATTTTTTTTTTTTTTTTAGTTTTACTTTCTTTTTATTCGGAAAAATCTTTTCTATATTT
TTCAAGGGTAACCTCATCGCCATGCAATTAATCACATAGACTCCTTAAGTAACAATGGCA
AGGCGATAATTTTAAGAGAATTGCAGACGCTGTACATAGATCGTTATCAGCAAAACATAT
ATTCGCATCGAAGGCGTTGCTTGTCCCTGAAGTAGCTACTTGCGGTTTTCATCAAGCGGC
CAATTTAATCATTCTATCAGCATTATTTTAAAATAGGGGGACTTAACCTTTCTATTAGTA
CCACTTATTTTATAGATCTGCTGGAGAAAAATAAACAGATAAAAAAAAGGGAAAAAAAGA
ATAAGACTGTCTTGGTGAGGATATTCAGTTGCGTGAAATC
Chr coordinates
Chr V from 523369-525759