Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
GRX4
Systematic Name
YER174C
Strain
S288c
Description
Glutathione-dependent oxidoreductase and glutathione S-transferase; hydroperoxide/superoxide-radical responsive monothiol glutaredoxin subfamily member with Grx3p and Grx5p; protects cells from oxidative damage with GRX3 and GRX5; with Grx3p, promotes dissociation of Aft1p from iron regulon gene promoters and subsequent nuclear export in iron-replete conditions, regulating iron homeostasis; involved with Grx3p in Sir2p deglutathionylation, restoring deacetylase activity after disulfide stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA
Hide Seq
>GRX4 YER174C
ATGACTGTGGTTGAAATAAAAAGCCAGGACCAATTTACGCAACTAACCACTACAAACGCT
GCTAATAAACTCATTGTCTTATATTTTAAAGCTCAATGGGCTGATCCTTGCAAAACTATG
AGCCAGGTGCTAGAAGCTGTTAGTGAAAAAGTTAGGCAAGAGGATGTCCGGTTTTTATCA
ATAGATGCAGACGAACATCCAGAAATATCAGACCTTTTTGAGATTGCAGCCGTACCATAC
TTCGTCTTCATTCAAAATGGTACTATTGTAAAAGAAATATCAGCCGCAGATCCTAAGGAG
TTTGTGAAAAGCTTAGAAATTCTTTCGAATGCTTCTGCCTCACTAGCGAACAATGCCAAG
GGTCCTAAATCTACGTCTGATGAGGAAAGCAGCGGGTCTTCCGATGATGAAGAGGACGAA
ACTGAAGAAGAAATAAATGCTAGGCTGGTGAAGCTAGTACAAGCTGCACCTGTGATGCTA
TTCATGAAAGGAAGCCCATCAGAACCTAAATGCGGATTTTCTAGACAGTTAGTTGGTATC
CTCAGAGAACACCAAATAAGGTTCGGATTTTTTGATATATTAAGAGACGAAAACGTTAGA
CAAAGCTTGAAGAAGTTTTCTGATTGGCCTACTTTTCCTCAGTTATATATCAATGGGGAG
TTCCAGGGAGGTTTGGATATTATCAAGGAATCTATAGAAGAAGATCCTGAATATTTCCAA
CATGCTCTACAGTAA
Promoter Sequence
Download FASTA
>GRX4 YER174C
GGAAGCGATCTCTCCGCTACCATGATTAAGACTGCAGAAGTAATAAAGGAAGGAAGTCCT
GATACATACAAAAACGTTTCATTTAAGATTTCTTCAAGTGATGATTTTAAATTCCTAGGC
GCGGATTCAGTAGACAAACAGAAAATTGATATGATTACCGCAGTAGAATGTGCTCATTGG
TTCGATTTCGAAAAATTTCAGCGATCTGCTTATGCCAATTTGAGAAAAGATGGTACTATC
GCTATTTGGGGTTATGCGGACCCAATTTTCCCGGACTACCCTGAATTTGATGATCTGATG
ATTGAAGTTCCTTACGGGAAGCAAGGACTGGGACCCTATTGGGAACAACCGGGGAGATCT
CGCCTTCGTAATATGCTGAAAGACTCTCACTTAGACCCAGAACTTTTCCATGATATACAA
GTTTCATATTTTTGTGCAGAAGATGTGAGAGACAAAGTAAAACTCCACCAGCATACAAAG
AAGCCATTGCTAATCAGAAAGCAGGTCACCCTAGTGGAGTTTGCAGATTATGTCAGAACC
TGGAGCGCTTACCATCAGTGGAAGCAGGATCCAAAGAACAAAGATAAAGAAGATGTAGCA
GATTGGTTTATTAAAGAGTCACTAAGGAGGAGGCCGGAACTTTCCACCAACACCAAAATT
GAAGTTGTTTGGAATACTTTTTACAAACTTGGCAAAAGGGTCTGAAAATTTCAGCCAATA
AGCATTATATTCGTGAAATTTTAGTAAGAGCGCGCGTTTTAATTGGTGAAGCCTCGCGAC
GTATTCACAGATGTCCTAGAAAAAGTTACCATATCTGAAGACTGGTTGATATTTAGCTTA
AATAGCATATTAATACTGTACCAGTTGAACCATTTTTTAATCTGTTACTGCCAGGAACGT
TGATTCGTTTTCCCGGTAACATTGTTGTCTTTGGGTACTGAGCATATTTCATTTTTCCAC
TTACATATAACTAAATTTCTGTGCTCTTCCTCCAATAAAT
Chr coordinates
Chr V from 539168-538434