Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
HAC1
Systematic Name
YFL031W
Alias
ERN4, IRE15
Strain
S288c
Description
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog); regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway triggers efficient Hac1p translation; two functional forms of Hac1p are produced; translation initiation is repressed under non-stress conditions; protein abundance increases in response to DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>HAC1 YFL031W
ATGGAAATGACTGATTTTGAACTAACTAGTAATTCGCAATCGAACTTGGCTATCCCTACC
AACTTCAAGTCGACTCTGCCTCCAAGGAAAAGAGCCAAGACAAAAGAGGAAAAGGAACAG
CGAAGGATCGAGCGTATTTTGAGAAACAGAAGAGCTGCTCACCAGAGCAGAGAGAAAAAA
AGACTACATCTGCAGTATCTCGAGAGAAAATGTTCTCTTTTGGAAAATTTACTGAACAGC
GTCAACCTTGAAAAACTGGCTGACCACGAAGACGCGTTGACTTGCAGCCACGACGCTTTT
GTTGCTTCTCTTGACGAGTACAGGGATTTCCAGAGCACGAGGGGCGCTTCACTGGACACC
AGGGCCAGTTCGCACTCGTCGTCTGATACGTTCACACCTTCACCTCTGAACTGTACAATG
GAGCCTGCGACTTTGTCGCCCAAGAGTATGCGCGATTCCGCGTCGGACCAAGAGACTTCA
TGGGAGCTGCAGATGTTTAAGACGGAAAATGTACCAGAGTCGACGACGCTACCTGCCGTA
GACAACAACAATTTGTTTGATGCGGTGGCCTCGCCGTTGGCAGACCCACTCTGCGACGAT
ATAGCGGGAAACAGTCTACCCTTTGACAATTCAATTGATCTTGACAATTGGCGTAATCCA
GAAGCGCAGTCAGGTTTGAATTCATTTGAATTGAATGATTTCTTCATCACTTCATGA
Promoter Sequence
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>HAC1 YFL031W
AGAGCCACTATCATCGGCGACTCCTGTGATCGTGTTCCACTGTGGAGAGCCATATCGCAC
CTTGCCGTCCAGTTCCAGCTCCAAGATCATACACGGATTCTTCTCTGTGGCCAGCTGCAG
ATATTTTTCATAATTGGAGGAAGTCAATGAGCTTGGGTTCGAATTCGATGATATCGGGGA
GAGCTTGTTTATGCCAAGTCCCTCTTTCATAGCCTGAGATCCGCCTGCGGTGTTACTTCT
ATTGAACATCTGTCTTCCTCTACTGGGCTTATCTATTCTATCAAATGAGGCAAGAGAAAG
GAAAGGGAAAAAAAAAAAGGGAAAATGCTTGATGAGTTAGGAATTCAGTAAAAGCACCCA
CCAGAACCTCTACAGCAGGCCTTCCAGGAGTGGTTAAGAGGATAGAGAATTCTGTATATA
TATATACGTCTATATCTATACAAAAAACGGCAGACAATGCAGAAGTTGAAAATGCTGTGA
TACGAACAACAACTTATTTTTACAATGAAAAACAACACCAAGCTGCCAAAAGCTGTATAT
TAAAGTTAAAGCTCCCTCATTTTTAGTAAGGACGCTTTCTTTTCCCACAAAAGGGACGAG
GAAAAAAAGAAAAACCTGGAAATATAGTCACGTGACATGAATAAACAAGACCTAGGGCAA
TATGGAAAAAGAAGCTAGGATAAAAATACATTTATGAGGGTTGTAAGGCAAAGTGGCTCA
GCATTAAGTAGGGCTAAAAAGAGTCGCAAATATACATCGTACCGAGTGATGAACGTGGTT
TTGAACACCTTGTTCTCTTTTGTTCTCGCTCCCTACATTCACTATATATTAGAAGAAATT
TCACCTCAATGGACAACTCGAGAAATGAATACAGAAATATGTTTTTTAGCGAAATTTTCC
TTTCTTCTTGTCTTCTTGTTTTATTTAAACTTCCAAGGCTTTAACTCAGTGTCAAACATA
ACAACCTCCTCCTCCCCCACCTACGACAACAACCGCCACT
Chr coordinates
Chr VI from 75179-75839,76092-76147