Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ROG3
Systematic Name
YFR022W
Alias
ART7
Strain
S288c
Description
Alpha-arrestin involved in ubiquitin-dependent endocytosis; contributes to desensitization of agonist-occupied alpha-factor receptor Ste2p by Rsp5p-independent internalization; PPXY motif-mediated binding of the ubiquitin ligase Rsp5p is not required for adaptation; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant; SWAT-GFP and mCherry fusion proteins localize to the cytosol; ROG3 has a paralog, ROD1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ROG3 YFR022W
ATGGGCTTCAGTAGCGGTAAATCAACTAAGAAAAAGCCTCTGCTTTTCGATATCAGACTT
AAAAATGTTGACAACGATGTAATACTCCTCAAAGGTCCTCCAAACGAGGCCCCCTCGGTG
CTTTTATCTGGTTGCATCGTTTTATCGATTAACGAACCCATGCAGATCAAAAGCATATCA
TTGAGACTTTATGGGAAGATACAAATAGACGTACCATTAGAGAGGCCCCAGGACGCTAGT
TCTTCGTCGTTGTCTTCATCGCCGCCAAAGATCAGAAAGTACAACAAAGTTTTTTATAAT
TACGCATGGGATAATGTTAACCTCAAGGAGTATCTGAGTGGTTTAAGAGGGCAATCTGGC
CTTGCGGGCAGTAGCTCATCAAGTAATATCTTGGGCACTCGCCAAAGAGCTCAGTCCACA
AGTTCCTTGAAGTCTTTAAAGGGGTCCTCCTCACCCTCTTCATGTACTTTAGATAAGGGC
AACTACGATTTTCCCTTTAGTGCTATTTTGCCTGGTTCGTTACCAGAGAGCGTAGAATCT
TTGCCAAATTGCTTCGTGACATATAGCATGGAATCCGTTATTGAACGCAGCAAAAATTAT
AGTGATTTGATCTGTAGGAAAAATATTAGAGTTCTGAGAACCATTTCACCCGCAGCAGTG
GAGTTATCAGAAACTGTTTGTGTAGATAACTCATGGCCCGACAAAGTGGATTATTCTATT
TCAGTACCCAACAAAGCCGTAGCTATTGGTTCAGCCACCCCTATAAATATTTCCATTGTA
CCTCTTTCGAAAGGTTTGAAATTGGGCTCAATCAAAGTCGTATTATTTGAGAATTATCAA
TATTGTGACCCCTTCCCTCCAGTAATTTCTGAAAATAGGCAAGTGACAGAACTAAATCTT
GAAGATCCCTTGAACGAGTCATCTGGAGAATTTAATGGTAATGGTTGCTTTGTAAATAAC
CCCTTTTTTCAGCCTGATCATTCATTCCAAGACAAGTGGGAGATTGATACCATCCTGCAA
ATCCCGAACAGCTTATCAAACTGTGTGCAAGATTGTGATGTCCGCTCTAACATTAAGGTT
CGCCATAAGCTCAAATTTTTCATCATCCTAATTAACCCAGATGGTCATAAATCTGAGTTA
AGAGCGTCCTTACCGATTCAACTTTTTATTTCACCATTTGTGGCACTTTCAATAAAACCA
TTGTCATCCTCGAATTTGTATTCGCTTTTTAGCACCACTAACCAGAAAGACGAAAACTCA
TCACAAGAAGAGGAAGAGGAATATCTGTTTTCTAGATCAGCATCAGTCACAGGGTTGGAA
TTATTAGCGGATATGCGTAGCGGTGGCTCTGTTCCTACCATTTCAGACTTGATGACGCCC
CCAAATTATGAAATGCACGTATATGATCGTCTTTATAGCGGTTCTTTCACTCGCACGGCT
GTGGAAACGTCTGGAACATGTACTCCTTTGGGAAGCGAATGTTCGACTGTCGAGGATCAG
CAACAGGATTTAGAAGATTTACGTATACGGTTGACAAAAATTAGAAATCAACGTGACAAT
CTAGGGCTACCACCGTCTGCCTCGTCTGCTGCCGCTTCCAGATCGCTATCTCCATTACTA
AACGTTCCAGCACCAGAGGATGGCACGGAGAGAATCTTACCTCAGAGTGCTCTTGGTCCC
AATAGTGGCTCTGTGCCAGGAGTACATAGTAACGTATCACCTGTTTTACTTTCAAGATCC
CCAGCCCCAAGCGTGTCAGCCCATGAAGTGTTACCAGTGCCCTCGGGCTTAAATTATCCA
GAGACTCAAAACCTGAACAAGGTTCCATCGTATGGCAAGGCAATGAAATATGATATCATT
GGTGAGGACCTTCCTCCTTCCTACCCTTGTGCGATACAAAATGTGCAACCAAGAAAACCC
AGTAGGGTACATTCCAGGAACTCTTCGACAACATTGTCATCTTCTATACCAACTAGCTTT
CATTCCTCTAGTTTTATGAGTAGCACTGCTTCCCCTATTTCCATAATTAATGGCTCTAGA
AGTAGTTCTAGTGGGGTATCTCTTAATACACTTAATGAGTTAACTTCGAAAACTTCGAAT
AACCCATCCAGTAATAGTATGAAAAGGTCACCAACAAGACGGAGGGCTACTTCTTTAGCT
GGGTTTATGGGAGGTTTTCTATCAAAGGGTAACAAACGATAG
Promoter Sequence
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>ROG3 YFR022W
ATGATTCATCGCTCGATACCACCAGTATCGATGCGCTGAGTGACGAGGAAAACCCGACAA
GACTCGCAAGAGAACCATATGTGGATGCATCAAGAAAGACAATGGGTAGGATGATACGTT
ACTCTTCTCAAAAGCTATCCCGAAGAGCTGCCAGAACATTGGGTCAGATTTTCCCCATCA
AAGTTACATCGTTGTTGGAATCCTCGCGCCATTTTGCGTCTTTGAAACTTCCCGTTGAAA
CCAATTCCCATGTAATGACCATATCAAGTATAGGCTCTCCAATAGATATAGACACATCCG
AGTATCCGGAACTCTTCGAAACTGGCAATTCCGCAAGTACAGAGTCCTACCATGAGCCTG
TTATGAAGATGGTCCCCATCAGGGTCGTTTCCTCGGATGGATACCTATACAACTTTGTTA
TGGACCCGGAGAGAGGCGGCGATTGCTTAATATTGTCACAGTATTCCATCTTGATGGATT
GATCACGGAAGTGTCTCGCGCTGCCTTCCGTACGTCACAACGCATACACAATATAGTTTA
TATAAACTCCTGCGTATAATCTATCCTTTTGCATAATATTTTCGTCACCATTATCTTGTT
GCGGTGTTTTTATTTAAAACAATAGAACTCGCCTAAAGGGGAAATTTTCGATATAAAAAT
TCAAAAAAATGGCTTTCATGGATCGAGTATTTGTTTGTCGAAAAAGGATCACTGGAGTGA
CGTTACTACGCTACGAAGCCTCCTTCCGGCTTAGCCCTGTTGATTACGAATTTGGATCAG
TTGGTATTTGATTCCTCGGAAGAGTTAACTTCACGCGGGTAAATCACTTGTGATGCGGTA
TATTCTCTATACGGCTAATAGATGAATCAGGGTGTTTTAAAGTGCGTATAAACCCTTTTG
CTATTTTCGTTTATATAATTGGCGTTGATAAAGAGCCAATATCTATTGTTGCTACATAGA
GGCAGCTCTCTTAGCAAAATAAAAATACAAAAAGTTCGAC
Chr coordinates
Chr VI from 196833-199034