Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
ERG26
Systematic Name
YGL001C
Strain
S288c
Description
C-3 sterol dehydrogenase; catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; human homolog NSDHL implicated in CK syndrome, and can complement yeast null mutant; molecular target of natural product and antifungal compound FR171456
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ERG26 YGL001C
ATGTCAAAGATAGATTCAGTTTTAATTATCGGTGGTTCTGGTTTTCTTGGATTGCACTTA
ATTCAGCAATTTTTTGATATTAATCCTAAGCCAGACATCCACATTTTTGATGTTAGAGAT
CTCCCTGAAAAACTTTCAAAACAGTTTACTTTTAATGTAGACGACATAAAATTTCATAAG
GGTGATTTAACATCACCTGATGATATGGAAAACGCAATTAACGAAAGTAAAGCAAATGTT
GTTGTTCATTGTGCTTCTCCAATGCATGGTCAAAATCCAGATATTTATGACATAGTGAAT
GTTAAGGGAACCCGTAACGTGATAGATATGTGCAAGAAATGTGGCGTTAATATACTTGTA
TATACTTCCTCTGCTGGTGTTATTTTTAATGGGCAAGATGTGCACAATGCAGACGAAACC
TGGCCAATCCCAGAAGTTCCTATGGATGCGTACAATGAGACTAAAGCTATCGCCGAAGAT
ATGGTCTTGAAGGCGAATGATCCAAGCAGTGATTTCTATACTGTTGCTCTTCGTCCAGCT
GGTATTTTTGGCCCAGGTGATAGGCAATTAGTACCTGGTCTAAGACAGGTTGCGAAATTG
GGGCAGTCGAAGTTCCAAATTGGTGATAATAACAATCTATTTGATTGGACTTATGCTGGA
AATGTTGCTGACGCGCATGTGTTAGCTGCACAGAAACTTCTCGATCCAAAAACAAGAACT
GCTGTCTCGGGTGAAACTTTTTTCATTACCAATGATACCCCCACCTATTTTTGGGCCTTG
GCCCGTACTGTGTGGAAGGCAGATGGTCATATTGATAAACATGTTATTGTTTTGAAAAGG
CCAGTTGCAATTTGTGCAGGTTATCTTTCAGAATGGGTATCCAAGATGCTGGGTAAAGAG
CCAGGTTTGACTCCATTCAGAGTCAAGATTGTGTGTGCATACCGTTATCACAACATTGCT
AAGGCCAAAAAGTTGCTAGGCTACACACCAAGAGTTGGTATTGAAGAAGGAATTAACAAA
ACGTTGGCCTGGATGGACGAAGGTTTGTAA
Promoter Sequence
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>ERG26 YGL001C
GTTAATTGACCCACCTTTTTTAAATGAAGATTGTCAAACAAAGTGTATGTATATCATAAA
CATATCCCTACTCATTTTTTAATCTTTTTTCCAGTATCTTTTCATCTTACTAACTGTTAT
TCATTGATATAAAATAGCCTCTATCACTGCAAAGTGTTTATTAGCGCCAAATGACAACTC
TAAAACTAAGAAAGGAGTTTTTAAGCACCGCCTCATAAGTTGTACTGGTGAAAGAATGTC
TGAAGTCATATCCAAAGTTTATTCTGACACAAGAATAACAACTTTTCTTCCTGAACATTC
TAATGGTTTGAGTAACGAATTTAGGTGCTACGCAAATTTTGAATGTAGTTCATGGAAATT
TGCTTCTTGAGCTTTTTAAGAGCTTCGATAAATTTGAAAATTAATTGTACTACATAAAAA
ATATGTAAACATCAATATATATAATATAATCACATTTCAAATATATCACGTGTTATATTT
ACTATATAAAAATTCAATAAATAAAAAGTTAGAAGATAAAAATTATATTATACATATTTT
TATTTTTATTATAATTTTTGTTTTTGCCTTCCGAAAAGAAAATAGTTTTTTGTATTACGG
AAATTACAGAAAAATGTTTAATTTTGATTTCATATTTTTTCTTTCTTTGAAAGAATATTG
ACGACAAAGTATTGGATAATTATAATGCAAGGAAAGGATATTTGTAGATCTTCGGTTCAA
TGAAAGTTAATGCGGTATGAATATTGCTTTCTCCAGGACCTTTTTTTTTTTTTAGAGGCT
ATTTTATTGTCGGTGTTTGTGGATTTTATATTTCTCGGTCCGATAGTCCCTATAGATCGT
TTATTGTTCTCTCGAGAAATGGTATCGTTTAAAAATCTCATATAAGCCTGCAAGGAAAAG
ATTATGCTGCAGCTATAAAATAGAATAGACAACAATATAGATTGTCAATTTTGTCCAATT
TTATTTGCAACTCTACCTGGAAGGGCAAACAAAAATAAAT
Chr coordinates
Chr VII from 496502-495453