Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PDR1
Systematic Name
YGL013C
Alias
AMY1, ANT1, BOR2, CYH3, NRA2, SMR2, TIL1, TPE1, TPE3
Strain
S288c
Description
Transcription factor that regulates the pleiotropic drug response; zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes; relocalizes to the cytosol in response to hypoxia; PDR1 has a paralog, PDR3, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PDR1 YGL013C
ATGCGAGGCTTGACACCTAAGAACGGTGTACATATTGAGACGGGTCCGGATACAGAATCG
TCCGCGGACTCCAGCAACTTTTCTACAGGTTTCAGCGGCAAGATTCGTAAGCCAAGGTCG
AAAGTAAGTAAAGCGTGCGATAACTGTAGAAAAAGAAAGATAAAATGTAATGGGAAGTTT
CCCTGCGCAAGCTGTGAGATATATTCATGTGAGTGCACGTTCAGCACTAGACAAGGTGGC
GCTCGAATAAAAAACCTTCACAAGACGAGTTTGGAAGGTACAACCGTACAAGTCAAAGAG
GAAACAGATTCCAGTTCGACTTCTTTTTCTAATCCTCAGCGATGTACAGACGGGCCATGC
GCAGTGGAACAACCAACGAAATTTTTTGAGAATTTCAAGCTAGGTGGTCGTAGTAGTGGT
GATAATAGCGGAAGTGATGGGAAGAATGACGACGATGTGAATAGAAACGGTTTTTATGAA
GACGATAGCGAATCACAGGCAACTTTGACATCTCTACAAACCACTCTGAAAAATTTGAAG
GAGATGGCTCATTTAGGTACACATGTAACCTCAGCCATCGAGAGCATTGAACTTCAGATA
AGTGACTTGCTTAAGCGATGGGAACCCAAAGTGAGGACCAAAGAATTAGCAACAACGAAA
TTTTACCCTAATAAATCAATAGAAACTCAATTGATGAAAAACAAATACTGTGATGTGGTA
CATTTGACAAGATATGCCGCTTGGTCAAACAATAAGAAGGACCAAGATACTTCTAGTCAA
CCTTTGATCGACGAAATCTTTGGTTTGTACTCTCCTTTCCAATTTTTGTCACTTCAAGGT
ATTGGTAAATGTTTCCAAAATTATAGATCCAAATCCAAATGCGAGATTTTTCCCAGGACC
GCCAAGGAAACCATATACATCATGTTAAGGTTTTTCGACGTTTGTTTTCATCACATCAAC
CAAGGCTGTGTCTCCATAGCTAATCCCCTGGAAAACTACCTACAGAAAATGAATCTTTTA
CCTTCAACCCCATCTTCGATATCATCTGCAGGGAGCCCGAATACAGCACACACAAAATCG
CATGTTGCGTTAGTGATAAATCACTTACCGCAGCCCTTTGTGAGAAATATAACCGGAATA
AGTAATTCTGAGCTACTAAGCGAAATGAATAATGATATCAGCATGTTTGGCATTTTATTG
AAGATGTTGGATATGCATAAAAATTCCTACCAGAACTTCCTAATGGAAATCACATCTAAC
CCCTCCGTGGCTAAAAACACGCAGTCAATTGATGTCTTGCAGGAATTCATCCATTATTGT
CAAGCTGGAGAGGCGCTAATCGCCTTATGTTACAGCTATTATAATTCTACATTATACAAC
TACGTGGACTTCACATGCGACATAACGCATTTAGAGCAACTTCTATACTTTTTGGATCTG
CTATTTTGGCTATCGGAAATATACGGTTTTGAAAAAGTCTTGAACGTAGCAGTTCATTTT
GTTTCAAGAGTTGGTTTATCAAGGTGGGAATTTTACGTGGGTCTTGATGAAAACTTTGCT
GAAAGAAGAAGAAATCTCTGGTGGAAAGCTTTCTATTTCGAGAAAACTTTAGCCTCTAAA
CTTGGCTATCCTTCGAACATTGATGACTCCAAAATCAATTGTTTATTACCTAAGAATTTT
CGAGATGTTGGGTTCTTGGATAATAGAGATTTTATCGAGAACGTCCACTTAGTTCGCAGG
AGCGAAGCTTTTGACAACATGTGCATATCCGACTTAAAATACTATGGCGAATTAGCTGTC
TTACAAATAGTCAGCCATTTCTCATCATCTGTTTTATTCAATGAAAAATTCACGTCAATT
AGGAATACATCAAAACCATCTGTTGTTAGAGAGAAACTACTCTTCGAGGTACTCGAGATT
TTTAACGAAACAGAAATGAAATATGATGCTATCAAAGAGCAAACTGGAAAATTGTTCGAT
ATTGCATTCTCTAAAGATAGTACTGAACTCAAAGTTTCAAGAGAGGATAAGATTATGGCT
TCAAAATTTGTTCTATTTTACGAGCACCATTTCTGCAGAATGGTTAACGAATCTGATAAT
ATTGTCGCCAGATTATGCGTGCACAGAAGGCCCTCAATACTAATTGAAAACTTGAAAATA
TACCTTCACAAGATTTACAAATCATGGACCGATATGAACAAAATCTTATTAGACTTTGAC
AACGATTATTCCGTATACCGTTCGTTCGCCCATTATTCTATCAGTTGCATTATTTTGGTA
TCACAAGCATTCTCAGTGGCCGAATTCATTAAAGTAAATGACGTTGTGAATATGATTAGA
GTCTTCAAAAGATTTTTGGATATAAAAATTTTTTCCGAAAATGAGACCAATGAGCATGTC
TTCAACAGCCAAAGCTTTAAAGACTATACAAGAGCTTTTTCTTTCCTGACAATCGTCACT
CGTATCATGCTTTTGGCATACGGAGAGTCCTCTAGCACCAACCTCGATGTTATCTCCAAA
TATATTGATGAGAATGCGCCAGATTTAAAAGGTATAATAGAACTTGTCTTGGATACAAAC
TCTTGCGCTTATCGATTTTTATTAGAACCTGTTCAGAAGTCAGGATTCCATTTAACGGTC
TCACAAATGTTGAAAAATAGAAAGTTTCAGGAACCACTAATGTCAAATGAAGATAATAAG
CAGATGAAGCATAATTCGGGAAAAAATTTGAATCCGGATCTCCCAAGTCTTAAGACGGGC
ACTTCATGCTTACTAAATGGCATTGAATCGCCTCAATTGCCATTCAATGGTCGCTCAGCA
CCTTCCCCAGTGAGAAACAACTCACTACCGGAGTTTGCACAATTGCCTTCATTTAGGTCA
TTATCCGTGTCTGATATGATCAATCCCGATTACGCGCAACCAACAAATGGGCAAAATAAT
ACGCAAGTCCAATCTAATAAACCAATCAATGCTCAGCAGCAAATACCCACTTCAGTACAA
GTACCATTTATGAACACAAATGAAATCAATAACAACAACAACAACAACAACAACAATAAA
AACAATATTAACAATATTAACAACAACAACAGTAACAATTTTTCTGCAACTAGTTTTAAT
TTGGGGACACTAGATGAATTTGTTAATAACGGTGATCTTGAGGACCTCTACAGTATCCTG
TGGAGCGACGTTTATCCAGATAGTTAA
Promoter Sequence
Download FASTA
>PDR1 YGL013C
ATACAAGGTCCACATGGCATTACAAAAGTAAGGCAATTGTTTTCCCTTCAAATGAGACAA
TGGTTGACCTTTTGTCCAAATCCCGGGCAACGTATAGTAGAAAATGATCTGAAACACCCA
AAATGTTAAGAAAATAGTCCAGTCATACTTTTCTGGGATACCGTTCTCCAAGACTAACTG
GTATAGGTGCTTGATAAAGTGCATCCACGATTCACCAGCCTTGGGTAGGGCAACCTTACC
GTGATAAAATTCCGCACAAATCCACATATAGTACATTAGCAGTGGAAACCCGATCAGCAT
ACCAATAACACCAGTAGTCCCACCAAACTCATATTCGATTTCATTTGGCTTCAGCCATTT
ACCCTGAGGCAGGAAATTAACCGGTTGCTTGGACTTTTTCTCCTCTCCCTGCACCTGCAG
CTTCTCACTATTATCCTTTGCCATAGCGATGCTAATCTATGTACACTACGTAAATATCCG
TATCTGCCTATCTACATAACTGAACTACATTCCTACGTTATTACCACTGTTTGGTAATTT
TTCCTCGAGGATATATAATTCTGCTTTTCCATAGTAACGCCAAACGATCGCGTAATACCG
GCAATTACGGGATGCACGAAAATAGCGCCAAGGAACGAAAAAGAAATGAGTCTCGTTTAG
TTATTAAACGAGAAGAAACGAGCCCTGATTTACATTCTCAGGGTCCAATAGGGCTTTGTT
GGAAACAGACGCATACCCTAAATGGAGTTTCTTTTCTTGTTCAAGACCTAATGAGTGGCA
ATAAGAGGCGCTAATTAAAGCTCTTCAAAACAACCTTATTCGCCTATTACACATGATCAG
CCACTCTTTCATTGTCAACAATAGCATGATAGCAGGACCATAGCGGCCATATAGACATTA
CCAGGAGTGAGTTTTGGCTAAAAAAAGACAATTTGCACATCACTTGCTAACTATTCATCT
CAGCCAAGAATATACAGAAAAGAATCCAAGAAACTGGAAG
Chr coordinates
Chr VII from 472298-469092