Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name PDR1
Systematic Name YGL013C
Alias AMY1, ANT1, BOR2, CYH3, NRA2, SMR2, TIL1, TPE1, TPE3
Strain S288c
Description Transcription factor that regulates the pleiotropic drug response; zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes; relocalizes to the cytosol in response to hypoxia; PDR1 has a paralog, PDR3, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>PDR1 YGL013C
ATGCGAGGCTTGACACCTAAGAACGGTGTACATATTGAGACGGGTCCGGATACAGAATCG
TCCGCGGACTCCAGCAACTTTTCTACAGGTTTCAGCGGCAAGATTCGTAAGCCAAGGTCG
AAAGTAAGTAAAGCGTGCGATAACTGTAGAAAAAGAAAGATAAAATGTAATGGGAAGTTT
CCCTGCGCAAGCTGTGAGATATATTCATGTGAGTGCACGTTCAGCACTAGACAAGGTGGC
GCTCGAATAAAAAACCTTCACAAGACGAGTTTGGAAGGTACAACCGTACAAGTCAAAGAG
GAAACAGATTCCAGTTCGACTTCTTTTTCTAATCCTCAGCGATGTACAGACGGGCCATGC
GCAGTGGAACAACCAACGAAATTTTTTGAGAATTTCAAGCTAGGTGGTCGTAGTAGTGGT
GATAATAGCGGAAGTGATGGGAAGAATGACGACGATGTGAATAGAAACGGTTTTTATGAA
GACGATAGCGAATCACAGGCAACTTTGACATCTCTACAAACCACTCTGAAAAATTTGAAG
GAGATGGCTCATTTAGGTACACATGTAACCTCAGCCATCGAGAGCATTGAACTTCAGATA
AGTGACTTGCTTAAGCGATGGGAACCCAAAGTGAGGACCAAAGAATTAGCAACAACGAAA
TTTTACCCTAATAAATCAATAGAAACTCAATTGATGAAAAACAAATACTGTGATGTGGTA
CATTTGACAAGATATGCCGCTTGGTCAAACAATAAGAAGGACCAAGATACTTCTAGTCAA
CCTTTGATCGACGAAATCTTTGGTTTGTACTCTCCTTTCCAATTTTTGTCACTTCAAGGT
ATTGGTAAATGTTTCCAAAATTATAGATCCAAATCCAAATGCGAGATTTTTCCCAGGACC
GCCAAGGAAACCATATACATCATGTTAAGGTTTTTCGACGTTTGTTTTCATCACATCAAC
CAAGGCTGTGTCTCCATAGCTAATCCCCTGGAAAACTACCTACAGAAAATGAATCTTTTA
CCTTCAACCCCATCTTCGATATCATCTGCAGGGAGCCCGAATACAGCACACACAAAATCG
CATGTTGCGTTAGTGATAAATCACTTACCGCAGCCCTTTGTGAGAAATATAACCGGAATA
AGTAATTCTGAGCTACTAAGCGAAATGAATAATGATATCAGCATGTTTGGCATTTTATTG
AAGATGTTGGATATGCATAAAAATTCCTACCAGAACTTCCTAATGGAAATCACATCTAAC
CCCTCCGTGGCTAAAAACACGCAGTCAATTGATGTCTTGCAGGAATTCATCCATTATTGT
CAAGCTGGAGAGGCGCTAATCGCCTTATGTTACAGCTATTATAATTCTACATTATACAAC
TACGTGGACTTCACATGCGACATAACGCATTTAGAGCAACTTCTATACTTTTTGGATCTG
CTATTTTGGCTATCGGAAATATACGGTTTTGAAAAAGTCTTGAACGTAGCAGTTCATTTT
GTTTCAAGAGTTGGTTTATCAAGGTGGGAATTTTACGTGGGTCTTGATGAAAACTTTGCT
GAAAGAAGAAGAAATCTCTGGTGGAAAGCTTTCTATTTCGAGAAAACTTTAGCCTCTAAA
CTTGGCTATCCTTCGAACATTGATGACTCCAAAATCAATTGTTTATTACCTAAGAATTTT
CGAGATGTTGGGTTCTTGGATAATAGAGATTTTATCGAGAACGTCCACTTAGTTCGCAGG
AGCGAAGCTTTTGACAACATGTGCATATCCGACTTAAAATACTATGGCGAATTAGCTGTC
TTACAAATAGTCAGCCATTTCTCATCATCTGTTTTATTCAATGAAAAATTCACGTCAATT
AGGAATACATCAAAACCATCTGTTGTTAGAGAGAAACTACTCTTCGAGGTACTCGAGATT
TTTAACGAAACAGAAATGAAATATGATGCTATCAAAGAGCAAACTGGAAAATTGTTCGAT
ATTGCATTCTCTAAAGATAGTACTGAACTCAAAGTTTCAAGAGAGGATAAGATTATGGCT
TCAAAATTTGTTCTATTTTACGAGCACCATTTCTGCAGAATGGTTAACGAATCTGATAAT
ATTGTCGCCAGATTATGCGTGCACAGAAGGCCCTCAATACTAATTGAAAACTTGAAAATA
TACCTTCACAAGATTTACAAATCATGGACCGATATGAACAAAATCTTATTAGACTTTGAC
AACGATTATTCCGTATACCGTTCGTTCGCCCATTATTCTATCAGTTGCATTATTTTGGTA
TCACAAGCATTCTCAGTGGCCGAATTCATTAAAGTAAATGACGTTGTGAATATGATTAGA
GTCTTCAAAAGATTTTTGGATATAAAAATTTTTTCCGAAAATGAGACCAATGAGCATGTC
TTCAACAGCCAAAGCTTTAAAGACTATACAAGAGCTTTTTCTTTCCTGACAATCGTCACT
CGTATCATGCTTTTGGCATACGGAGAGTCCTCTAGCACCAACCTCGATGTTATCTCCAAA
TATATTGATGAGAATGCGCCAGATTTAAAAGGTATAATAGAACTTGTCTTGGATACAAAC
TCTTGCGCTTATCGATTTTTATTAGAACCTGTTCAGAAGTCAGGATTCCATTTAACGGTC
TCACAAATGTTGAAAAATAGAAAGTTTCAGGAACCACTAATGTCAAATGAAGATAATAAG
CAGATGAAGCATAATTCGGGAAAAAATTTGAATCCGGATCTCCCAAGTCTTAAGACGGGC
ACTTCATGCTTACTAAATGGCATTGAATCGCCTCAATTGCCATTCAATGGTCGCTCAGCA
CCTTCCCCAGTGAGAAACAACTCACTACCGGAGTTTGCACAATTGCCTTCATTTAGGTCA
TTATCCGTGTCTGATATGATCAATCCCGATTACGCGCAACCAACAAATGGGCAAAATAAT
ACGCAAGTCCAATCTAATAAACCAATCAATGCTCAGCAGCAAATACCCACTTCAGTACAA
GTACCATTTATGAACACAAATGAAATCAATAACAACAACAACAACAACAACAACAATAAA
AACAATATTAACAATATTAACAACAACAACAGTAACAATTTTTCTGCAACTAGTTTTAAT
TTGGGGACACTAGATGAATTTGTTAATAACGGTGATCTTGAGGACCTCTACAGTATCCTG
TGGAGCGACGTTTATCCAGATAGTTAA
Promoter Sequence
Download FASTA
>PDR1 YGL013C
ATACAAGGTCCACATGGCATTACAAAAGTAAGGCAATTGTTTTCCCTTCAAATGAGACAA
TGGTTGACCTTTTGTCCAAATCCCGGGCAACGTATAGTAGAAAATGATCTGAAACACCCA
AAATGTTAAGAAAATAGTCCAGTCATACTTTTCTGGGATACCGTTCTCCAAGACTAACTG
GTATAGGTGCTTGATAAAGTGCATCCACGATTCACCAGCCTTGGGTAGGGCAACCTTACC
GTGATAAAATTCCGCACAAATCCACATATAGTACATTAGCAGTGGAAACCCGATCAGCAT
ACCAATAACACCAGTAGTCCCACCAAACTCATATTCGATTTCATTTGGCTTCAGCCATTT
ACCCTGAGGCAGGAAATTAACCGGTTGCTTGGACTTTTTCTCCTCTCCCTGCACCTGCAG
CTTCTCACTATTATCCTTTGCCATAGCGATGCTAATCTATGTACACTACGTAAATATCCG
TATCTGCCTATCTACATAACTGAACTACATTCCTACGTTATTACCACTGTTTGGTAATTT
TTCCTCGAGGATATATAATTCTGCTTTTCCATAGTAACGCCAAACGATCGCGTAATACCG
GCAATTACGGGATGCACGAAAATAGCGCCAAGGAACGAAAAAGAAATGAGTCTCGTTTAG
TTATTAAACGAGAAGAAACGAGCCCTGATTTACATTCTCAGGGTCCAATAGGGCTTTGTT
GGAAACAGACGCATACCCTAAATGGAGTTTCTTTTCTTGTTCAAGACCTAATGAGTGGCA
ATAAGAGGCGCTAATTAAAGCTCTTCAAAACAACCTTATTCGCCTATTACACATGATCAG
CCACTCTTTCATTGTCAACAATAGCATGATAGCAGGACCATAGCGGCCATATAGACATTA
CCAGGAGTGAGTTTTGGCTAAAAAAAGACAATTTGCACATCACTTGCTAACTATTCATCT
CAGCCAAGAATATACAGAAAAGAATCCAAGAAACTGGAAG
Chr coordinates Chr VII from 472298-469092
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