Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ALK1
Systematic Name
YGL021W
Strain
S288c
Description
Atypical protein kinase; along with paralog, ALK2, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of cell polarity factors in mitosis, proper localization of formins and polarity factors, and survival in cells that activate spindle assembly checkpoint; regulates the morphogenesis checkpoint in response to polarity insults through inactivation of Mih1p; phosphorylated in response to DNA damage; similar to mammalian haspins
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ALK1 YGL021W
ATGCTACTTCATTTTGACATTGTAATTCAATTACTATCAAGTCATACCCTTAAATCGCAC
CAAGTAGAGCCCCCCATGGATTTTGAAACGTCGTTCGAAGAATTTGTCGAAGATAAACGA
TTCATTGCTCTAGAGGTATCTGATAATGATGACGATTGTGACACTGATTTGACTGCTGAC
ACAGCTGACGAGCTGGAAAGCTCTGCTATCTTAAAGATGAGGGAGTCTGATGCATCTTTA
AATGTTACCACCGGCAATAATACATCAAGGAAAACGACTTCCAATTCCAAAAAACGATGG
TCTCTATTATCCAATCATTCTGCTGTTTCATCATCTAAATCTAAGAAAAGATGGTCTGTA
CTTTCTTCAAGCTTTACCAGTGAATCTCATAAGGACAGGGAATCGAGGAACGTTTTGCAA
CAAAAAAGAAAATCCTTGCAGAGTTATTCAAGCTTAGATACGGTAGCATCTAATAGCTCT
ATCTCTGCTTCTTCTTCTTTGAAAAGATCGTCCACTGGTCTTTCCCTCAGACAATTGTTT
ACCAAGATAGGCATAAACGATGATATATCACAACCTGGGATCGGGATTCCGCAAGGTAAG
GAAAATCTGCCTCCAACTATGGGCAAAAAAAATTCATCAATTGCTTCCACTAGTTCGGAA
AACAGACTTAGGACACCATTGAAGCCGCTTGTTAATCATTCTAAAAGGCCCACTTCACAA
CCACAACAGCAACAACCACTATATAATGCATCATTGTCCTCGAGAAGATCGTCGATTTCT
TCCACTGTCTCTTCTTCCAGCTCGTCTAAATGGAGATTCTGGAAGAGAAATAAGAACCAG
ACACCTGCATTGTTGCAACCAGACCACCATTCTTTAAAAACCTTTCCTGCAGTAAACCGT
CGTGATTCCATGACGCCCGTTGAACCAAGAAATATGGTAAAACATAAGACATCCTTTTCA
GATTTCCATAAGACTATCTTCAGTTCAAATACGTATTCTGAAAGCAGCGATACAATATCT
TCCATGGAAATTACTTTGAAAAACAAAGCTTCTTCCTCAAGTCTATCTTTGAACGTGTTG
AAGAAAAGGAATTCGCAATCAAGTTTGAAGCACAAAAGTTCACATGCATCCTTACAAAAA
TTCAAAAGAAACAAAGGAAAGTCCTCCATGATAGCACCATCGACAGCAACTAATAGCAGC
AATGATGACTCTTGTAGCTACAGTTCCAAAAATTCTACGTTGAGTCACCGAATATCGTTA
CCTGTACCGGACCAAGTTTCCCGTGATAAAATTCAGAACAAATTAAGATATTCGACCTCA
TTACTCTCATTAAATTCTAAATCATCTTTACCGATGAACAAAAATGATCATGATGAGACA
CTTCTAAGACAGATTTTACTAAATTGTGATATAAAGAGAATTTTAAACCCCGCAAAAGGA
GATGTATTGCCTTTAATCAACGATGTAAACCATTTGTCATCAATACAATTAACATCAAAT
GTTTGGCAAATTGGTGAAGTAATCTGTAAAAAAGTTTCTCTCGGTACTATTGATGACATT
ACATGGGATAGAAAGTTCTTATCTTTGCAGGAACTGGAAAAACTCAAAATCATGCAACAA
AAATTTGATGGCATACCGCAACTATTGAAAAGTTTTGTTGTTAAAGAGGCAAATGGGGGG
TTGTATTTGTACTTACTATTCAAAGATCACGGTACCCCAATTTCGTTAATCTCACTGAAA
AACTGGAAGCAGATTCTAAAGATTTTTTGGTCTTGTGCTGGTATAATTCATGGGTTGGAA
AAAAATTTGAAATTTGAACATCGTAATCTTACTTTGGATAATATTTTGATAGATGGTAAT
GGGAATATAACAATTATTGATTTTAAATGCAGTAGATTGCAAACTCCTCAAGATGATGTT
TTATATCTACGGCTAGATCATCCACTCTTTTTTCTAAATGGGAAAGACAAGAGTAAAATA
AACGAATACCAGTATCAATTTGAGTTTGAAATCTATCAAAGTATGCGGATCTTGTTGAAC
ATGGACGCGTCAGCTTTTGAGCCCATGACAAATTTGTATTGGTTATATTACCTGTCACGC
GTTTTACTAAAGTTTGGTGACAGGAAGCTTGGTAAGAATGATGCAAACAGGGATAAAATG
GCAAGGGTGATAAACCATTTGGAAATGAACTTGGCAGTTCATAAAAGAGGGGGGCAGTTA
TTCAAAAGATTGGAGACGGAGGACATTAAGAATACTGGAGATTTACTAAAACTTTATAAA
TAA
Promoter Sequence
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>ALK1 YGL021W
TTTTCGTCTTCCATTCTACTTGGGTAACAAGAACTGCATACTCTTCTCCTTCTGTTGTTT
TGCCATCACAAACCCCAGATGGTAAATTGGCGTTGATCGACGACTTCAGGGAAGCGTACT
ATTGGTTAAGAATGAACTCTGATGAGGACAGTAAGGTTGCAGCGTGGTGGGATTACGGTT
ACCAAATTGGTGGCATGGCAGACAGAACCACTTTAGTCGATAACAACACGTGGAACAATA
CTCACATCGCCATCGTTGGTAAAGCCATGGCTTCCCCTGAAGAGAAATCTTACGAAATTC
TAAAAGAGCATGATGTCGATTATGTCTTGGTCATCTTTGGTGGTCTAATTGGGTTTGGTG
GTGATGACATCAACAAATTCTTGTGGATGATCAGAATTAGCGAGGGAATCTGGCCAGAAG
AGATAAAAGAGCGTGATTTCTATACCGCAGAGGGAGAATACAGAGTAGATGCAAGGGCTT
CTGAGACCATGAGGAACTCGCTACTTTACAAGATGTCCTACAAAGATTTCCCACAATTAT
TCAATGGTGGCCAAGCCACTGACAGAGTGCGTCAACAAATGATCACACCATTAGACGTCC
CACCATTAGACTACTTCGACGAAGTTTTTACTTCCGAAAACTGGATGGTTAGAATATATC
AATTGAAGAAGGATGATGCCCAAGGTAGAACTTTGAGGGACGTTGGTGAGTTAACCAGGT
CTTCTACGAAAACCAGAAGGTCCATAAAGAGACCTGAATTAGGCTTGAGAGTCTAAATTG
GCCACACATTAAAGGAAATGACTAAGATAAAATATACATATATAAAAAGATAAACAAATA
AGTATAAGTTTGGTTTCCCTTCCCGTTATTATGATCGCTCGTGACGGATCGTCTTTGCCC
TTTTTGGTAAAACGTAAACAAAATAACAATAGAAAAAATAACAACTTTATCAATGTTTAT
TTTTATTTATTAAGTATTTGATGTGAAGTAGTTTTTCTAA
Chr coordinates
Chr VII from 454785-457067